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CAS No 40391-99-9 , (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid

  • Name: (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid
  • Synonyms: 40391-99-9; Acide pamidronique [INN-French]; Amidronate; Acido pamidronico [INN-Spanish]; Aredia;PAMIDRONIC ACID;(3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid; Aminomux;
  • CAS Registry Number:
  • Melting Point: 226-228 ºC
  • Flash Point: 352.2 ºC
  • Boiling Point: 658.7 ºC at 760 mmHg
  • Density: 1.998 g/cm3
  • Refractive index: 1.611
  • Flash Point: 352.2 ºC
  • EINECS: 254-905-2
  • Molecular Weight: 235.069464
  • InchiKey: WRUUGTRCQOWXEG-UHFFFAOYSA-N
  • InChI: InChI=1S/C3H11NO7P2/c4-2-1-3(5,12(6,7)8)13(9,10)11/h5H,1-2,4H2,(H2,6,7,
    8)(H2,9,10,11)
  • Molecular Formula: C3H11NO7P2
  • Molecular Structure:CAS No:40391-99-9 (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid
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40391-99-9 Pamidronic acid

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40391-99-9 Pamidronic Acid

  • China Zibo Dingjin Chemical Co.,Ltd. [Manufacturers]
  • Tel: +86-(533)-533-6955, 533-5955
  • Fax: +86-(533)-533-4766
  • Address: Shuangfeng Technological & Industrial Zone(Huayang Pharm), Zibo, Shandong 255190, zibo,shandongChina
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40391-99-9 Pamidronic acid

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40391-99-9 Pamidronate disodium

  • Pamidronate disodium, 98%
  • China Nanjing Chemzam Pharmtech Co., Ltd. [Manufacturers]
  • Tel: +86-25-68936071, 86462165,+86-13915979898
  • Fax: +86-25-68847170
  • Address: C5-1,6 Maiyue Road,Maigaoqiao,Nanjing,Jiangsu,China null,JiangsuChina
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40391-99-9 Pamidronic Disodium

  • Pamidronic Disodium
  • China China-Japan Shandong Hongfuda Pharmachem Co [Manufacturer]
  • Tel: 86 531 88870708
  • Fax: 86 531 88870908
  • Address: West unit,F bldg,South garden,Jinan Hightec Zone,Shandong ,China250100 JinanCHINA Jinan,nullChina
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40391-99-9 3-amino-1-hydroxypropylidene-1,1-bisphosphonic acid

  • 3-amino-1-hydroxypropylidene-1,1-bisphosphonic acidPamidronate
  • France Surfactis Technologies [Manufacturer]
  • Tel: +33 2 41 34 95 03
  • Fax: +33 2 72 22 04 67
  • Address: 22, rue roger Amsler AngersFRANCE Angers,nullFrance
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40391-99-9 disodium(3-amino-1-hydroxypropylidene)bisphosphonatepentahydrate

  • disodium(3-amino-1-hydroxypropylidene)bisphosphonatepentahydrate
  • China zhongshan enantiotech corporation limited [Manufacturers]
  • Tel: 0086-760-85282625
  • Fax: 0086-760-85282626
  • Address: Zhongjing Road, Zhongshan Torch Hi-tech Industrial Development Zone, zhongshan,nullChina
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40391-99-9 Pamidronic acid

  • Pamidronic acid Pamidronate disodium Disodium Pamidronate (3-Amino-1-hydroxypropylidene)bisphosphonic acid Pamidronate disodium Intermdiates Pamidronic Disodium Aminomux Pamedronate disodium salt Pamidronate Disodium Salt Pamidronic acid sodium salt ...
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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40391-99-9 Pamidronate disodium

  • Pamidronate disodium
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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References of (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid
Title: Pamidronic Acid
CAS Registry Number: 40391-99-9
CAS Name: (3-Amino-1-hydroxypropylidene)bisphosphonic acid
Synonyms: 3-amino-1-hydroxypropane-1,1-diphosphonic acid; ADP; AHPrBP
Molecular Formula: C3H11NO7P2
Molecular Weight: 235.07
Percent Composition: C 15.33%, H 4.72%, N 5.96%, O 47.64%, P 26.35%
Literature References: Bisphosphonate antiresorptive agent. Prepn: F. Krueger et al., DE 2130794 (1973 to Benckiser), C.A. 78, 84528z (1973); K.-H. Worms et al., Z. Anorg. Allg. Chem. 457, 214 (1979). Improved process: H. Blum, K.-H. Worms, US 4327039 (1982 to Henkel). Mechanism of action study: P. M. Boonekamp et al., Bone Miner. 1, 27 (1986). HPLC determn in serum and plasma: R. W. Sparidans et al., J. Chromatogr. B 705, 331 (1998). Clinical trial to prevent postmenopausal bone loss: B. Lees et al., Osteoporos. Int. 6, 480 (1996). Review of pharmacology and therapeutic use in resorptive bone disease: A. Fitton, D. McTavish, Drugs 41, 289-318 (1991); A. J. Coukell, A. Markham, Drugs Aging 12, 149-168 (1998).
 
Derivative Type: Disodium salt
CAS Registry Number: 57248-88-1
Synonyms: Pamidronate disodium
Manufacturers' Codes: GCP-23339A
Trademarks: Aminomux (Gador); Aredia (Novartis)
Molecular Formula: C3H9NNa2O7P2
Molecular Weight: 279.03
Percent Composition: C 12.91%, H 3.25%, N 5.02%, Na 16.48%, O 40.14%, P 22.20%
 
Therap-Cat: Bone resorption inhibitor.
Keywords: Antiosteoporotic; Antipagetic; Bone Resorption Inhibitor.