References of (2R)-2-amino-3-(4-hydroxy-2-methylbutan-2-yl)sulfanylpropanoic acid
Title: Felinine
CAS Registry Number: 471-09-0
CAS Name: S-(3-Hydroxy-1,1-dimethylpropyl)-L-cysteine
Synonyms: L-3-[(3-hydroxy-1,1-dimethylpropyl)thio]alanine; (-)-felinine
Molecular Formula: C8H17NO3S
Molecular Weight: 207.29
Percent Composition: C 46.35%, H 8.27%, N 6.76%, O 23.16%, S 15.47%
Line Formula: HOOCCH(NH2)CH2SC(CH3)2CH2CH2OH
Literature References: Sulfur containing amino acid; occurs as L-(-)-form in cat urine. Isoln: R. G. Westall,
Biochem. J. 55, 244 (1953). Synthesis of (±)-felinine: S. Trippett,
J. Chem. Soc. 1957, 1929; of (-)-felinine: H. Eggerer,
Ann. 657, 212 (1962); A. Sch?berl
et al., Ber. 101, 373 (1968).
Properties: Needles from water + acetone, dec 177°. [a]D25 -11.5° (c = 2.81 in water). Sol in water, ethanol. Practically insol in acetone, ethyl acetate, ether.
Optical Rotation: [a]D25 -11.5° (c = 2.81 in water)
Derivative Type: (±)-Felinine
Properties: Crystals from aq ethanol, dec 181°.