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CAS No 4828-27-7 , Clocortolone

  • Name: Clocortolone
  • Synonyms: Clocortolone;(6S,9R,16R)-9-Chloro-6-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one;
  • CAS Registry Number:
  • Melting Point: 254
  • Density: 1.32 g/cm3
  • Refractive index: 1.579
  • EINECS: 225-406-7
  • Molecular Weight: 410.91
  • InChI: InChI=1/C22H28ClFO4/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-21(15,3)22(14,23)18(28)9-20(13,2)19(11)17(27)10-25/h4-5,7,11,13-14,16,18-19,25,28H,6,8-10H2,1-3H3/t11-,13+,14+,16+,18+,19-,20+,21+,22+/m1/s1
  • Molecular Formula: C22H28ClFO4
  • Molecular Structure:CAS No:4828-27-7 Clocortolone

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4828-27-7 Clocortolone

  • Clocortolone ??AS NO.??4828-27-7 We produce: Desonide 638-94-8 Flumethasone 2135-17-3 Diflucortolone valerate 59198-70-8 Deflazacort 14484-47-0 Desoximetasone 382-67-2 Difluprednate 23674-86-4 Fludrocortisone 514-36-3 Halobetasol Propionate 66852-54-...
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References of Clocortolone
Title: Clocortolone
CAS Registry Number: 4828-27-7
CAS Name: (6a,11b,16a)-9-Chloro-6-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
Synonyms: 9-chloro-6a-fluoro-16a-methyl-1,4-pregnadiene-11b,21-diol-3,20-dione
Molecular Formula: C22H28ClFO4
Molecular Weight: 410.91
Percent Composition: C 64.30%, H 6.87%, Cl 8.63%, F 4.62%, O 15.57%
Literature References: Prepn: NL 6412708; E. K. Kaspar, R. Philippson, DE 2011559; eidem, US 3729495 (1965, 1971, 1973 all to Schering AG). Clinical trials: Wortmann, Wien. Med. Wochenschr. 122, 701 (1972); Baumann, Praxis 61, 536 (1972).
Properties: Crystals from methanol-methylene chloride, mp 254° (dec).
Melting point: mp 254° (dec)
 
Derivative Type: 21-Acetate
CAS Registry Number: 4258-85-9
Manufacturers' Codes: SH-818
Molecular Formula: C24H30ClFO5
Molecular Weight: 452.94
Percent Composition: C 63.64%, H 6.68%, Cl 7.83%, F 4.19%, O 17.66%
Properties: Crystals from methanol-methylene chloride, mp 252° (dec).
Melting point: mp 252° (dec)
 
Derivative Type: 21-Pivalate
CAS Registry Number: 34097-16-0
Manufacturers' Codes: CL-68; SH-863
Trademarks: Cloderm (Ortho); Purantix (Wander)
Molecular Formula: C27H36ClFO5
Molecular Weight: 495.02
Percent Composition: C 65.51%, H 7.33%, Cl 7.16%, F 3.84%, O 16.16%
 
Therap-Cat: Glucocorticoid.
Keywords: Glucocorticoid.