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CAS No 489-32-7 , Icariin Search by region : United States

  • Name: Icariin
  • Synonyms: 3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one;Icariin;Icariine; Horny goat weed extract; Icariln; Epimedium; Epimediun P.E.; Ieariline; Epimedium extract; Horny goat weed extract; 3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one; Icariln; Ieariline; Epimedium extract;
  • CAS Registry Number:
  • Melting Point: 223-225 ºC
  • Density: 1.55
  • Refractive index: 1.679
  • Molecular Weight: 676.65
  • InChI: InChI=1/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1
  • Molecular Formula: C33H40O15
  • Molecular Structure:CAS No:489-32-7 Icariin

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489-32-7 Icariin

  • Icariin is a flavonol and PDE5 inhibitor with IC50 of 1.0, 0.75, and 1.1 uM for PDE5A1, A2, and A3, respectively. More information please visit the website: http://www.creative-enzymes.com/product/Icariin_2202.html
  • Min. Order: 10
  • United States Creative Enzymes [Manufacturer]
  • Tel: 1-516-6698109
  • Fax: 1-631-9388127
  • Address: 45-1 Ramsey Road, Shirley New York,New YorkUnited States
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489-32-7 Epimedium Brevicornum

  • United States Alfa Chem []
  • Tel: +1-(516)-504-0059, 800-375-6869
  • Fax: +1-(516)-504-0039
  • Address: 2 Harbor Way, Kings Point, New York 11024, ,United States
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489-32-7 ICARIIN(P)

  • United States ChromaDex Inc. [Manufacturer]
  • Tel: 949-419-0288
  • Fax: 949-419-0294
  • Address: ChromaDex Inc.
    10005 Muirlands Blvd. Suite G - First Floor
    Irvine, CA 92618 ,United States
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References of Icariin
Title: Epimedii Herba
Synonyms: Yinyanghuo
Literature References: Chinese herbal medicine made from the dried aerial parts of Epimedium sp. (Berberidaceae). Used as a tonic and in the treatment of rheumatic disease and hypertension. Principal constituents are prenylflavone glycosides such as icariin, epimedosides, sagittatosides, and baohuosides. Isoln of icariin from E. macranthum: S. Akai, J. Pharm. Soc. Jpn. 55, 537 (1935), C.A. 29, 5850 (1935). Revised structure: Y. Tokuoka et al., Yakugaku Zasshi 95, 825 (1975), C.A. 83, 111172r (1975). HPLC determn of constituents: M. Mizuno et al., Chem. Pharm. Bull. 36, 3487 (1988); Y. Ito et al., J. Chromatogr. 456, 392 (1988). Immunoregulatory effects of icariin in vitro: W. He et al., Arzneim.-Forsch. 45, 910 (1995). Review: W. Tang, G. Eisenbrand in Chinese Drugs of Plant Origin (Springer-Verlag, Berlin, 1992) pp 491-498.
 
Derivative Type: Icariin
CAS Registry Number: 489-32-7
CAS Name: 3-[(6-Deoxy-a-L-mannopyranosyl)oxy]-7-(b-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
Synonyms: 4¢-O-methyl-8-g,g-dimethylallylkaempferol-3-rhamnoside-7-glucoside
Molecular Formula: C33H40O15
Molecular Weight: 676.66
Percent Composition: C 58.57%, H 5.96%, O 35.47%
Properties: Sesquihydrate, mp 231.5°. [a]D15 -87.09° (in pyridine). Sol in pyridine. Insol in water, alcohol, chloroform, acetone, methanol, ethyl acetate.
Melting point: mp 231.5°
Optical Rotation: [a]D15 -87.09° (in pyridine)