Home > Name List By other > (8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10, 13-dimethyl-1,2,6,7,8,9,11,12,14,15,16, 17-dodecahydrocyclope...

CAS No 50-22-6 , (8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,
13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,
17-dodecahydrocyclopenta[a]phenanthren-3-one

  • Name: (8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,
    13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,
    17-dodecahydrocyclopenta[a]phenanthren-3-one
  • Synonyms: Corticosteron; Kendall's compound B; Compound B;17-Deoxycortisol; 50-22-6; Reichstein's substance H;(8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,
    13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,
    17-dodecahydrocyclopenta[a]phenanthren-3-one; Reichstein's B;
  • CAS Registry Number:
  • Melting Point: 179-183 °C(lit.)
  • Flash Point: 288°C
  • Boiling Point: 529.2°Cat760mmHg
  • Density: 1.21g/cm3
  • Refractive index: 1.575
  • Safety Statements: 36-22
  • Hazard Symbols: Xi,N,Xn,T
  • Flash Point: 288°C
  • EINECS: 200-019-6
  • Molecular Weight: 346.4605
  • InchiKey: OMFXVFTZEKFJBZ-HJTSIMOOSA-N
  • InChI: InChI=1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)
    21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,
    16+,17-,19+,20-,21-/m0/s1
  • Risk Statements: R43
  • Molecular Formula: C21H30O4
  • Molecular Structure:CAS No:50-22-6 (8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,<br />13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,<br />17-dodecahydrocyclopenta[a]phenanthren-3-one

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50-22-6 Corticosterone crystalline

  • Corticosterone crystalline
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
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50-22-6 Corticosterone

  • Corticosterone
  • Germany CHEMOS GmbH [Manufacturer]
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References of (8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,
13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,
17-dodecahydrocyclopenta[a]phenanthren-3-one
Title: Corticosterone
CAS Registry Number: 50-22-6
CAS Name: (11b)-11,21-Dihydroxypregn-4-ene-3,20-dione
Synonyms: 4-pregnene-11b,21-diol-3,20-dione; Kendall's compound B; Reichstein's substance H
Manufacturers' Codes: compd B
Molecular Formula: C21H30O4
Molecular Weight: 346.46
Percent Composition: C 72.80%, H 8.73%, O 18.47%
Literature References: Endogenous glucocorticoid; intermediate in the biosynthesis of aldosterone from progesterone. Isoln from adrenal cortex: Mason et al., J. Biol. Chem. 114, 613 (1936); Reichstein, von Euw, Helv. Chim. Acta 21, 1197 (1938); Jeanloz et al., US 2676904 (1954 to Searle); from adrenal extract: Reichstein, US 2166877 (1939 to Roche-Organon). Prepn from desoxycholic acid: Wallis, Chakravorty, US 2341250 (1944 to Research Corp.); from 11-deoxycorticosterone: Zaffaroni, US 2671752 (1954 to Syntex); from cortisone: Oliveto et al., US 2927108 (1960 to Schering).
Properties: Trigonal plates from acetone, mp 180-182°. [a]D15 +223° (c = 1.1 in alc). uv max: 240 nm. Insol in water. Sol in usual organic solvents. Upon moistening with concd H2SO4 it gives an orange-yellow soln which has a strong fluorescence.
Melting point: mp 180-182°
Optical Rotation: [a]D15 +223° (c = 1.1 in alc)
Absorption maximum: uv max: 240 nm
 
Derivative Type: 21-Acetate
Molecular Formula: C23H32O5
Molecular Weight: 388.50
Percent Composition: C 71.11%, H 8.30%, O 20.59%
Properties: Clusters of needles from acetone + ether, mp 145°. [a]D20 +195° (c = 0.62 in acetone).
Melting point: mp 145°
Optical Rotation: [a]D20 +195° (c = 0.62 in acetone)