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CAS No 50-81-7 , (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one Search by region : United States

  • Name: (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
  • Synonyms: Cebione; Ascorbicap; Cecon; Cevalin; ascorbate;(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one; vitamin C; Ascoltin; Cevex;l-ascorbic acid;
  • CAS Registry Number:
  • Melting Point: 190-192 ºC
  • Density: 1,65 g/cm3
  • Refractive index: 21 ° (C=10, H2O)
  • Alpha: 20.5 º (C=10,H2O)
  • Water Solubility: 333 G/L (20 ºC)
  • Safety Statements: S24/25
  • Hazard Symbols: Xn
  • EINECS: 200-066-2
  • Molecular Weight: 176.12412
  • InchiKey: CIWBSHSKHKDKBQ-JLAZNSOCSA-N
  • InChI: InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,
    5+/m0/s1
  • Risk Statements: S24/25
  • Molecular Formula: C6H8O6
  • Molecular Structure:CAS No:50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one

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50-81-7 L-Ascorbic Acid (1-13C, 99%)

  • Creative Proteomics provides a full range of drug development services, including Molecular Biology, Biochemistry, Systems Biology, Organic Chemistry, Genomics, Bioinformatics, Structural Biology, Preclinical and Clinical studies. Please contact us t...
  • United States Creative Proteomics [Manufacturer, Trading Company]
  • Tel: 1-631-6197922
  • Fax: 1-631-6147828
  • Address: 45-1 Ramsey Road, Shirley New York,New YorkUnited States
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50-81-7 L-Ascorbic Acid (U-13C6, 98%)

  • Creative Proteomics provides a full range of drug development services, including Molecular Biology, Biochemistry, Systems Biology, Organic Chemistry, Genomics, Bioinformatics, Structural Biology, Preclinical and Clinical studies. Please contact us t...
  • United States Creative Proteomics [Manufacturer, Trading Company]
  • Tel: 1-631-6197922
  • Fax: 1-631-6147828
  • Address: 45-1 Ramsey Road, Shirley New York,New YorkUnited States
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50-81-7 L-(+)-Ascorbic acid

  • L-(+)-Ascorbic acidVitamin C, >99.5%
  • United States INDOFINE Chemical Co., Inc. [Manufacturer]
  • Tel: (908) 359-6778
  • Fax: (908) 359-1179
  • Address: 121 Stryker Lane
    Bldg 30, Suite 1
    Hillsborough, NJ 08844 ,United States
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50-81-7 Ascorbic acid

  • Ascorbic acid
  • United States Chem-Impex International, Inc. [Manufacturer]
  • Tel: 630 766 2112
  • Fax: 630 766 2218
  • Address: 935 Dillon Drive Wood Dale IL 60191 USA ,United States
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50-81-7 L(+)-Ascorbic acid

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: Union City,CaliforniaUnited States
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50-81-7 NETTLE EXTRACT

  • NETTLE EXTRACT, 1%
  • United States INTERNATIONAL LABORATORY LIMITED [Manufacturer]
  • Tel: ( 650 ) 278-9963
  • Fax: ( 650 ) 589-2786
  • Address: 1067 SNEATH LN SAN BRUNO CA 94066, USA SAN BRUNOUNITED STATES SAN BRUNO,United States
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50-81-7 KAEMPFEROL(AHP)

  • KAEMPFEROL(AHP)
  • United States ChromaDex Inc. [Manufacturer]
  • Tel: 949-419-0288
  • Fax: 949-419-0294
  • Address: ChromaDex Inc.
    10005 Muirlands Blvd. Suite G - First Floor
    Irvine, CA 92618 ,United States
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50-81-7 Cevitamic Acid

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50-81-7 ASCORBIC ACID D/C 97

  • United States Aceto Corp. [Manufacturer]
  • Tel: 516-627-6000
  • Fax: 516-627-6093
  • Address: One Hollow Lane
    Lake Success, NY 11042-1215 ,United States
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50-81-7 L-ASCORBIC ACID

  • L-ASCORBIC ACID
  • United States Charkit Chemical Corporation [Manufacturer]
  • Tel: 203-299-3220
  • Fax: 203-299-1355
  • Address: Charkit Chemical Corporation
    32 Haviland Street
    Norwalk, Connecticut 06854-4906 ,United States
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References of (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
Title: Ascorbic Acid
CAS Registry Number: 50-81-7
CAS Name: L-Ascorbic acid
Synonyms: vitamin C; 3-oxo-L-gulofuranolactone; L-threo-hex-2-enonic acid g-lactone; L-3-keto-threo-hexuronic acid lactone; L-xylo-ascorbic acid; antiscorbutic vitamin; cevitamic acid
Trademarks: Ascorbicap (Valeant); Ascorbin (Montavit); Ascorvit (Jenapharm); Cantan (Aventis); Cebion (Merck KGaA); Cecon (Abbott); Celaskon (Leciva); Celin (GSK); Cetebe (GSK); Cevalin (Lilly); Ce-Vi-Sol (BMS); Cevitan (Aventis); Cewin (Sanofi-Synthelabo); C-Vimin (AstraZeneca); Hicee (Takeda); Hybrin (Pfizer); Laroscorbine (Roche); Redoxon (Roche); Ribena (GSK); Vitacimin (Takeda); Vitacin (Towa Yakuhin); Vitascorbol (Aventis)
Molecular Formula: C6H8O6
Molecular Weight: 176.12
Percent Composition: C 40.92%, H 4.58%, O 54.51%
Literature References: Physiological antioxidant. Coenzyme for a number of hydroxylation reactions; required for collagen synthesis. Widely distributed in plants and animals. Most primates (including humans), guinea pigs, and some birds and fish cannot synthesize ascorbic acid. Inadequate intake results in deficiency syndromes such as scurvy. Dietary sources include citrus fruits, potatoes, peppers, broccoli, cabbage, and rose hips. First isolated from the adrenal cortex of ox and later from lemons and paprika (originally called hexuronic acid): A. Szent-Gy?rgyi, Biochem. J. 22, 1387 (1928); W. N. Haworth, A. Szent-Gy?rgyi, Nature 131, 24 (1933). Structure studies: R. W. Herbert et al., J. Chem. Soc. 1933, 1270. Synthesis: R. G. Ault et al., ibid. 1419; T. Reichstein et al., Helv. Chim. Acta 16, 561, 1019 (1933); 17, 311, 510 (1934). Review of discovery, structure and synthesis: E. L. Hirst, Fortschr. Chem. Org. Naturst. 2, 132-159 (1939). Crystal structure: J. Hvoself, Acta Chem. Scand. 18, 841 (1964). Review of syntheses: T. C. Crawford, S. A. Crawford, Adv. Carbohydr. Chem. 37, 79-155 (1980). HPLC determn in plasma: J. Lykkesfeldt et al., Anal. Biochem. 229, 329 (1995). Discussion of use in the treatment of the common cold: L. Pauling, Proc. Natl. Acad. Sci. USA 68, 2678 (1971); H. Hemil?, Scand. J. Infect. Dis. 26, 1 (1994). Clinical applications in immunology, lipid metabolism and cancer: Int. J. Vitam. Nutr. Res. 1982, Suppl. 23, 294 pp. Comprehensive description: I. A. Al-Meshal, M. M. A. Hassan, Anal. Profiles Drug Subs. 11, 45-78 (1982). Reviews: G. M. Jaffe in Kirk-Othmer Encyclopedia of Chemical Technology vol. 24 (John Wiley & Sons, New York, 3rd Ed., 1984) pp 8-40; "Vitamin C" in Vitamins, W. Friedrich, Ed. (Walter de Gruyter, Berlin, 1988) pp 929-1001. Review of pharmacology and clinical applications: M. Levine, N. Engl. J. Med. 314, 892-902 (1986); H. E. Sauberlich, Annu. Rev. Nutr. 14, 371-391 (1994).
Properties: Crystals (usually plates, sometimes needles, monoclinic system). Pleasant, sharp acidic taste. mp 190-192° (some dec). d 1.65. [a]D25 +20.5 to +21.5° (c = 1 in water); [a]D23 +48° (c = 1 in methanol). pH = 3 (5 mg/ml); pH = 2 (50 mg/ml); pK1 = 4.17; pK2 = 11.57. uv max at pH 2: 245 nm (E1%1cm 695); at pH 6.4: 265 nm (E1%1cm 940). Redox potential (first stage): E10 +0.166 V (pH 4). One gram dissolves in about 3 ml water, 30 ml alc, 50 ml abs alc, 100 ml glycerol, 20 ml propylene glycol. Soly in water: 80.0% at 100°; 40.0% at 45°. Insol in ether, chloroform, benzene, petr ether, oils, fats, fat solvents. Strong reducing agent. Stable to air when dry; aq solns are rapidly oxidized by air.
Melting point: mp 190-192° (some dec)
pKa: pK1 = 4.17; pK2 = 11.57
Optical Rotation: [a]D25 +20.5 to +21.5° (c = 1 in water); [a]D23 +48° (c = 1 in methanol)
Absorption maximum: uv max at pH 2: 245 nm (E1%1cm 695); at pH 6.4: 265 nm (E1%1cm 940)
Density: d 1.65
 
Derivative Type: Calcium hypophosphite
Synonyms: Asphocalcium
Trademarks: Calscorbat (Aerocid)
Molecular Formula: C6H9CaO8P
Molecular Weight: 280.18
Percent Composition: C 25.72%, H 3.24%, Ca 14.30%, O 45.68%, P 11.05%
 
Derivative Type: Calcium salt
CAS Registry Number: 5743-27-1
Synonyms: Calcium ascorbate
Molecular Formula: C12H14CaO12
Molecular Weight: 390.31
Percent Composition: C 36.93%, H 3.62%, Ca 10.27%, O 49.19%
Literature References: Prepn: Ruskin, Merrill, Science 105, 504 (1947).
Properties: Dihydrate, triclinic crystals, [a]D20 +95.6° (c = 2.4). Freely sol in water. Practically insol in methanol, ethanol.
Optical Rotation: [a]D20 +95.6° (c = 2.4)
 
Derivative Type: Sodium salt
CAS Registry Number: 134-03-2
Synonyms: Sodium ascorbate
Trademarks: Cenolate (Abbott); Xitix (Woelm)
Molecular Formula: C6H7NaO6
Molecular Weight: 198.11
Percent Composition: C 36.38%, H 3.56%, Na 11.60%, O 48.46%
Literature References: Prepn: Holland, US 2442005 (1948).
Properties: Minute crystals, dec 218°. [a]D20 +104.4°. Soly in water: 62 g/100 ml at 25°; 78 g/100 ml at 75°.
Optical Rotation: [a]D20 +104.4°
 
Use: As antimicrobial and antioxidant in foodstuffs.
Therap-Cat: Vitamin (antiscorbutic).
Therap-Cat-Vet: Vitamin (antiscorbutic).
Keywords: Vitamin/Vitamin Source; Vitamin C.