Home > Name List By 5 > 5-fluoro-1-[(2R,4S, 5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione Canada

CAS No 50-91-9 , 5-fluoro-1-[(2R,4S,
5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione Search by region : Canada

  • Name: 5-fluoro-1-[(2R,4S,
    5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
  • Synonyms: Floxuridin; FUDR; Fluorodeoxyuridine; Deoxyfluorouridine;5-fluoro-1-[(2R,4S,
    5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; 50-91-9;2'-Deoxy-5-fluorouridine; Fluoruridine deoxyribose; 5-Fluorodeoxyuridine;
  • CAS Registry Number:
  • Transport: UN 2811
  • Melting Point: 148-153 ºC
  • Density: 1.64 g/cm3
  • Refractive index: 1.608
  • Alpha: 35.9 º (C=1, WATER)
  • Safety Statements: R22;R36/37/38;R68
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 200-072-5
  • Molecular Weight: 246.192443
  • InchiKey: ODKNJVUHOIMIIZ-RRKCRQDMSA-N
  • InChI: InChI=1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,
    5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
  • Risk Statements: S26;S36/37/39
  • Molecular Formula: C9H11FN2O5
  • Molecular Structure:CAS No:50-91-9 5-fluoro-1-[(2R,4S,<br />5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

Related products

Select to

50-91-9 5-Fluoro-2'-deoxyuridine

  • 5-Fluoro-2'-deoxyuridine
  • Canada General Intermediates of Canada, Inc. [Manufacturer]
  • Tel: 780-483-2783
  • Fax: 780-483-2971
  • Address: General Intermediates of Canada, Inc.
    17303 - 108 Avenue
    Edmonton, Alberta
    CANADA T5S 1G2 null,nullCanada
Contact Supplier

50-91-9 FLOXURIDINE-D3

  • Canada Synth?se AptoChem Inc. [Manufacturer]
  • Tel: 514-496-4252
  • Fax: 514-496-4253
  • Address: Synth?se AptoChem Inc.
    6100 Royalmount Ave
    Montreal, QC
    Canada
    H4P 2R2 null,nullCanada
Contact Supplier

50-91-9 (+)-5-Fluoro-2'-deoxyuridine

Contact Supplier

Select to

1/1
References of 5-fluoro-1-[(2R,4S,
5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Title: Floxuridine
CAS Registry Number: 50-91-9
CAS Name: 2￠-Deoxy-5-fluorouridine
Synonyms: 1-(2-deoxy-b-D-ribofuranosyl)-5-fluorouracil; 5-fluoro-2￠-deoxy-b-uridine
Manufacturers' Codes: NSC-27640
Trademarks: FUDR (Roche)
Molecular Formula: C9H11FN2O5
Molecular Weight: 246.19
Percent Composition: C 43.91%, H 4.50%, F 7.72%, N 11.38%, O 32.49%
Literature References: Prepn: Hoffer et al., J. Am. Chem. Soc. 81, 4112 (1959); Heidelberger, Duschinsky, US 2885396 (1959); Duschinsky et al., US 2970139 (1961); Hoffer, US 2949451; US 3041335 (1960, 1962 both to Hoffmann-La Roche). Structure: Lemieux, Hoffer, Can. J. Chem. 39, 110 (1961). Crystal and molecular structure: Harris, Diss. Abstr. 24, 4425 (1964); Harris, McIntyre, Biophys. J. 4, 203 (1964). Conformation of furanose ring in molecule: Sundaralingam, J. Am. Chem. Soc. 87, 599 (1965).
Properties: Crystals from butyl acetate, mp 150-151° (Hoffer, 1959); also reported as mp 145° (US 3041335). [a]D +37° (water), +48.6° (DMF). uv max (pH 7.2): 268 nm (e 7570); (pH 14): 270 nm (e 6480).
Melting point: mp 150-151° (Hoffer, 1959); mp 145° (US 3041335)
Optical Rotation: [a]D +37° (water), +48.6° (DMF)
Absorption maximum: uv max (pH 7.2): 268 nm (e 7570); (pH 14): 270 nm (e 6480)
 
Derivative Type: a-Anomer
Synonyms: 1-(2-Deoxy-a-D-erythro-pentofuranosyl)-5-fluorouracil
Properties: Crystals from butyl acetate, mp 150-151°. [a]D25 -21° (c = 2 in water).
Melting point: mp 150-151°
Optical Rotation: [a]D25 -21° (c = 2 in water)
 
Therap-Cat: Antiviral; antineoplastic.
Keywords: Antineoplastic; Antimetabolites; Pyrimidine Analogs; Antiviral; Purines/Pyrimidinones.