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CAS No 506-26-3 , gamma-Linolenic acid Search by region : Germany

  • Name: gamma-Linolenic acid
  • Synonyms: (Z,Z,Z)-6,9,12-Octadecatrienoic acid;gamma-Linolenic acid;
  • CAS Registry Number:
  • Flash Point: 276.4°C
  • Boiling Point: 379.5°Cat760mmHg
  • Density: 0.924g/cm3
  • Refractive index: n20/D 1.471
  • Safety Statements: S26S36
  • Hazard Symbols: Xi
  • Flash Point: 276.4°C
  • Molecular Weight: 278.43
  • InChI: InChI=1/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10,12-13H,2-5,8,11,14-17H2,1H3,(H,19,20)/b7-6-,10-9-,13-12-
  • Risk Statements: 36/37/38
  • Molecular Formula: C18H30O2
  • Molecular Structure:CAS No:506-26-3 gamma-Linolenic acid

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506-26-3 6,9,12-Octadecatrienoicacid, (6Z,9Z,12Z)-

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References of gamma-Linolenic acid
Title: g-Linolenic Acid
CAS Registry Number: 506-26-3
CAS Name: (6Z,9Z,12Z)-6,9,12-Octadecatrienoic acid
Synonyms: cis-6,cis-9,cis-12-octadecatrienoic acid; gamolenic acid; GLA
Trademarks: Viacutan (Boehringer, Ing.)
Molecular Formula: C18H30O2
Molecular Weight: 278.43
Percent Composition: C 77.65%, H 10.86%, O 11.49%
Literature References: Polyunsaturated fatty acid produced in the body as the D6-desaturase metabolite of linoleic acid, q.v. Converted to dihomo-g-linolenic acid, a biosynthetic precursor of monoenoic prostaglandins such as PGE1. Present to varying extents in the fatty acid fraction of evening primrose oil (7-10%), in borage oil (18-26%), in black currant oil (15-20%) and in oils from different fungal sources (6-24%). Isoln from evening primrose oil, q.v.: A. Heiduschka, K. Luft, Arch. Pharm. 257, 33 (1919). Proposed structure: Eibner et al., Chem. Umschau. 34, 312 (1927). Confirmation of structure: J. P. Riley, J. Chem. Soc. 1949, 2728. Discussion of occurrence, esp. in fungi: R. Shaw, Biochim. Biophys. Acta 98, 230 (1965). Synthesis: J. M. Osbond et al., J. Chem. Soc. 1961, 2779; J. M. Osbond, ibid. 5270. Metabolism studies: J. F. Mead, D. R. Howton, J. Biol. Chem. 229, 575 (1957); K. J. Stone et al., Lipids 14, 174 (1979). Effect of source on essential fatty acid and prostanoid metabolite formation: D. K. Jenkins et al., Med. Sci. Res. 16, 525 (1988).
 
Derivative Type: Hexabromide deriv
Molecular Formula: C18H30Br6O2
Molecular Weight: 757.85
Percent Composition: C 28.53%, H 3.99%, Br 63.26%, O 4.22%
Properties: Crystals from ethyl methyl ketone, mp 201-202°.
Melting point: mp 201-202°
 
Use: Nutrient.
Therap-Cat: In treatment of atopic eczema.
Therap-Cat-Vet: Dermatological.
Keywords: Antieczematic.