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CAS No 51-21-8 , 5-fluoro-1H-pyrimidine-2,4-dione

  • Name: 5-fluoro-1H-pyrimidine-2,4-dione
  • Synonyms: 5-Fluorouracil; Carac; Fluoroplex; Adrucil; Fluracil; Efudex; 5-FU; Fluoroblastin; fluorouracil;5-fluoro-1H-pyrimidine-2,4-dione; 51-21-8;
  • CAS Registry Number:
  • Transport: UN 2811 6.1/PG 3
  • Melting Point: 278-286 ºC
  • Density: 1.53 g/cm3
  • Refractive index: 1.542
  • Water Solubility: 12.2 G/L 20 ºC
  • Safety Statements: R20/21/22
  • Hazard Symbols: Xn: Harmful;
  • HS Code: 29335995
  • EINECS: 200-085-6
  • Molecular Weight: 130.077223
  • InchiKey: GHASVSINZRGABV-UHFFFAOYSA-N
  • InChI: InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
  • Risk Statements: S36/37
  • Molecular Formula: C4H3FN2O2
  • Molecular Structure:CAS No:51-21-8 5-fluoro-1H-pyrimidine-2,4-dione
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51-21-8 5-FLUORO URACIL EXTRA PURE

  • 5-FLUORO URACIL EXTRA PURE
  • India Alpha Chemika [Manufacturer]
  • Tel: +91-22-22061123
  • Fax: +91-22-22061123
  • Address: 240,Dr.C.H.SREET,Dhobi talav.,behind parsi Dairy , Marine lines(E),MUMBAI-400 002. INDIA INDIA ,nullIndia
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51-21-8 5-FLUORO URACIL EXTRA PURE

  • 5-FLUORO URACIL EXTRA PURE
  • India alpha chemika [Manufacturer]
  • Tel: 91-22-22061123 / 56382501 / 56218147
  • Fax: 91-22-22061123
  • Address: 240,Dr.C.H.SREET,Dhobi talav.,behind parsi Dairy , Marine lines(E) 400 002 MUMBAIINDIA 400 002 MUMBAI,nullIndia
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51-21-8 5-FLUOROURACIL

  • China NINGBO V&P CHEMISTRY [Manufacturer]
  • Tel: 86-574-27666767
  • Fax: 86-574-56704282
  • Address: 21/F, NO.11 BLDG,XIN TIAN DI,
    NO689, SHI JI ROAD,
    NINGBO,CHINA, 315040 null,nullChina
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51-21-8 Fluorouracil

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51-21-8 5-Fluorouracil

  • 5-Fluorouracil
  • China Triomphe Fine Chemistry Co., Ltd. [Importer/Exporter]
  • Tel: +86-(21)-65127018
  • Fax: +86-(21)-65127019
  • Address: Shanghai Songjiang Industrial Park, Shanghai 200080, SHANGHAI,SHANGHAIChina
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51-21-8 5-FLUOROURACIL

  • United States AMRESCO Inc. [Manufacturer]
  • Tel: 440-349-1313
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  • Address: AMRESCO Inc.
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    Solon, OH 44139 null,nullUnited States
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51-21-8 5-Fluorouracil

  • China Shanghai Hanhong Chemicals [Manufacturers]
  • Tel: +86-13671516988 / 15921687200
  • Fax: +86-21-54291107
  • Address: Room207, No1 Building, Jiachuan Road245, Shanghai City, CHina Shanghai,ShanghaiChina
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51-21-8 5-Fluorouracil

  • China Hangzhou Hysen Pharma Co.,Ltd [Manufacturers]
  • Tel: 0571-89937472
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  • Address: ROOM 808, C# Zi Jin PLAZA , NO. 701, Gu'Dun ROAD hangzhou,zhejiangChina
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51-21-8 5-FLUOROURACIL

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51-21-8 5-Fluorouracil

  • China ZunAn Commerce & Industrial Co., Ltd. [Importer/Exporter]
  • Tel: 锛?86-755-82910159, 82910995,82910996
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  • Address: Room 3007, United Plaza A, Binhe Road 5022, Shenzhen, P.R.China Shenzhen,GuangdongChina
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References of 5-fluoro-1H-pyrimidine-2,4-dione
Title: Fluorouracil
CAS Registry Number: 51-21-8
CAS Name: 5-Fluoro-2,4(1H,3H)-pyrimidinedione
Synonyms: 2,4-dioxo-5-fluoropyrimidine; 5-FU
Manufacturers' Codes: Ro-2-9757; NSC-19893
Trademarks: Adrucil (Adria); Arumel (SS Pharm.); Efudex (Roche); Efudix (Roche); Fluril; Fluracil; Fluoroplex (Allergan); Fluroblastin (Farmitalia); Fluro Uracil; Timazin (Torii)
Molecular Formula: C4H3FN2O2
Molecular Weight: 130.08
Percent Composition: C 36.93%, H 2.32%, F 14.61%, N 21.54%, O 24.60%
Literature References: Prepn: Duschinsky et al., J. Am. Chem. Soc. 79, 4559 (1957); Heidelberger, Duschinsky, US 2802005 (1957); US 2885396 (1959); Barton et al., J. Org. Chem. 37, 329 (1972); O. Miyashita et al., Chem. Pharm. Bull. 29, 3181 (1981). Pharmacokinetics: W. Sadee, C. G. Wong, Clin. Pharmacokinet. 2, 437 (1977). Site of action: F. Maley, G. F. Maley, FEBS Symp. 57, 21 (1979). Comprehensive description: B. C. Rudy, B. Z. Senkowski, Anal. Profiles Drug Subs. 2, 221-244 (1973); S. M. Bayomi, A. A. Al-Badr, ibid. 18, 599-639 (1989). Review of clinical trials: R. M. Hansen, Cancer Invest. 9, 637-642 (1991).
Properties: Crystals from water or methanol-ether, dec 282-283°. Sublimes (0.1 mm) 190-200°. uv max (0.1N HCl): 265-266 nm (e 7070).
Absorption maximum: uv max (0.1N HCl): 265-266 nm (e 7070)
 
Derivative Type: Sodium salt
Trademarks: Effluderm (Allergan)
 
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Antimetabolites; Pyrimidine Analogs.