Home > Name List By other > (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid

CAS No 51-35-4 , (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid

  • Name: (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid
  • Synonyms: trans-L-Hydroxyproline; L-4-hydroxyproline;L-Hydroxyproline; Hypro; trans-Hydroxyproline; hydroxyproline;(2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid; hydroxy-L-proline; trans-4-Hydroxy-L-proline;
  • CAS Registry Number:
  • Melting Point: 274-275 ºC
  • Flash Point: 168.6 ºC
  • Boiling Point: 355.2 ºC at 760 mmHg
  • Density: 1.395 g/cm3
  • Refractive index: -75.5 ° (C=4, H2O)
  • Alpha: -75.5 º (C=5, H2O)
  • Water Solubility: 357.8 G/L (20 º C)
  • Safety Statements: 36/37/38,
  • Hazard Symbols: Xi:;
  • HS Code: 29339990
  • Flash Point: 168.6 ºC
  • EINECS: 200-091-9
  • Molecular Weight: 131.12986
  • InchiKey: PMMYEEVYMWASQN-DMTCNVIQSA-N
  • InChI: InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,
    4+/m1/s1
  • Risk Statements: S24/25
  • Molecular Formula: C5H9NO3
  • Molecular Structure:CAS No:51-35-4 (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid
Search by region :

Select to

51-35-4 L-Hydroxyproline

Contact Supplier

51-35-4 H-HYP-OH

  • United States Ivy Fine Chemicals [Manufacturer]
  • Tel: 856-465-8550
  • Fax: 856-616-1161
  • Address: Ivy Fine Chemicals
    1312 Bunker Hill Drive
    Cherry Hill, NJ 08003
    USA null,nullUnited States
Contact Supplier

51-35-4 trans-4-Hydroxy-L-proline

  • China Shanghai GL Peptide Ltd [Manufacturers]
  • Tel: 86-21-61263381
  • Fax: 86-21-61263399
  • Address: 519 Ziyue Road, Minhang, Shanghai, China Shanghai,ShanghaiChina
Contact Supplier

51-35-4 301875 TRANS-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID H-DL-HYP-OH; TRANS-4-HYDROXY-DL-PROLINE

  • Germany chemcube UG [Manufacturer]
  • Tel: +49 (22 08) 7 75 04 06
  • Fax: +49 (22 08) 7 75 02 30 /
    +49 (32 12) 1 00 74 76
  • Address: chemcube UG
    Salierweg 1
    53859 Niederkassel
    Germany null,nullGermany
Contact Supplier

51-35-4 trans-4-Hydroxy-L-proline

  • China Lanzhou boc chemical Co., Ltd [Manufacturers]
  • Tel: +86-931-4612200
  • Fax: +86-931-2105977
  • Address: Room4010, No.1328 ,Yanxi Road,Yantan Industrial Park, Lanzhou City, China PRC Lanzhou,gansuChina
Contact Supplier

51-35-4 (2S,4R)-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID

  • China Avosyn Chemical [Manufacturer]
  • Tel: +86-21-68870871
  • Fax: +86-21-68870871
  • Address: Hangzhou Gulf Fine Chemical Zone,
    Zhejiang, 312300, China null,nullChina
Contact Supplier

51-35-4 HYDROXYPROLINE BIOCHEMICA

  • Germany AppliChem GmbH [Manufacturer]
  • Tel: +49 6151 93 57 0
  • Fax: +49 6151 93 57 11
  • Address: AppliChem GmbH
    Ottoweg 4
    64291 Darmstadt
    Germany null,nullGermany
Contact Supplier

51-35-4 AG-21302 H-HYP-OH

  • United Kingdom AGTC Bioproducts Ltd [Manufacturer]
  • Tel: +44(0)1482646020
  • Fax: +44(0)1482646013
  • Address: AGTC Bioproducts Ltd
    Unit 4 Fleet Business Park, Hessle,
    ERY, HU13 9LX
    United Kingdom null,nullUnited Kingdom
Contact Supplier

51-35-4 L-Hydroxyproline

Contact Supplier

51-35-4 trans-4-Hydroxy-L-proline

  • China A & Z Food Additives.Co.,Ltd [Importer/Exporter]
  • Tel: 0086 571 85126931
  • Fax: 0086 571 85126959
  • Address: gucui road Hang zhou,Zhe JiangChina
Contact Supplier

Select to

References of (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid
Title: Hydroxyproline
CAS Registry Number: 51-35-4
CAS Name: (4R)-4-Hydroxy-L-proline
Synonyms: Hyp; Ls-hydroxyproline; (-)-(2S,4R)-4-hydroxyproline; trans-4-hydroxyproline; 4(R)-hydroxy-2(S)-pyrrolidinecarboxylic acid
Molecular Formula: C5H9NO3
Molecular Weight: 131.13
Percent Composition: C 45.80%, H 6.92%, N 10.68%, O 36.60%
Literature References: Amino acid analog of proline, q.v.; non-essential for human development. Shows cis-trans isomerism. Constituent of collagen, q.v. Isoln from gelatin: E. Fischer, Ber. 35, 2660 (1902). Synthesis: H. Leuchs, Ber. 38, 1937 (1905); and structure determn: H. Leuchs, J. F. Brewster, Ber. 46, 986 (1913). Stereochemistry: Hudson, Neuberger, J. Org. Chem. 15, 24 (1950). Early chemistry and biochemistry: Amino Acids and Proteins, D. M. Greenberg, Ed. (Charles C. Thomas, Springfield, IL, 1951) 950 pp., passim; J. P. Greenstein, M. Winitz, Chemistry of the Amino Acids vols 1-3 (John Wiley and Sons, Inc., New York, 1961) pp. 2018-2042, passim. Flow sheets of four different syntheses: Chem. Eng. News 40, 40 (Nov. 12, 1962). One pot synthesis: S. G. Ramaswamy, E. Adams, J. Org. Chem. 42, 3440 (1977). Proof of occurence in plants: D. Ashford, A. Neuberger, Trends Biochem. Sci. 5, 245 (1980). Effects of cis-trans isomerism on protein structure: N. Panasik, Jr. et al., Int. J. Pept. Protein Res. 44, 262 (1994). Review: R. Kuttan, A. N. Radhakrishnan, Adv. Enzymol. 37, 273-348 (1973). Review of metabolism: E. Adams, L. Frank, Annu. Rev. Biochem. 49, 1005-1061 (1980).
Properties: Rhombs or needles from water, mp 274°. [a]D -76.5° (c = 2.5 in water). pK1¢ 1.82; pK2¢ 9.65. Soly in water at 0°: 288.6 g/l; at 25°: 361.1 g/l; at 50°: 451.8 g/l; at 65°: 516.7 g/l. Very slightly sol in alcohol. Insol in ether.
Melting point: mp 274°
pKa: pK1¢ 1.82; pK2¢ 9.65
Optical Rotation: [a]D -76.5° (c = 2.5 in water)
 
Derivative Type: cis-Form
CAS Registry Number: 618-27-9
Synonyms: Allohydroxyproline; (2S,4S)-4-hydroxyproline
Properties: mp 238-241°. [a]D18 -58.1° (c = 5.2 in water).
Melting point: mp 238-241°
Optical Rotation: [a]D18 -58.1° (c = 5.2 in water)