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CAS No 516-12-1 , 1-iodopyrrolidine-2,5-dione

  • Name: 1-iodopyrrolidine-2,5-dione
  • Synonyms: NIS; Succinimide; SBB056268;1-iodopyrrolidine-2,5-dione; N-iodo-; Succiniodimide; n-iodo succinimide; EINECS 208-221-6; 1-Iodopyrrolidine-2,5-dione;516-12-1;
  • CAS Registry Number:
  • Transport: 25kgs
  • Melting Point: 197-204 ºC (DEC.)
  • Density: 2,245 g/cm3
  • Safety Statements: R22;R36/37/38
  • Hazard Symbols: Xn: Harmful;
  • HS Code: 29251995
  • EINECS: 208-221-6
  • Molecular Weight: 224.98453
  • InchiKey: LQZMLBORDGWNPD-UHFFFAOYSA-N
  • InChI: InChI=1S/C4H4INO2/c5-6-3(7)1-2-4(6)8/h1-2H2
  • Risk Statements: S26;S37/39
  • Molecular Formula: C4H4INO2
  • Molecular Structure:CAS No:516-12-1 1-iodopyrrolidine-2,5-dione

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References of 1-iodopyrrolidine-2,5-dione
Title: N-Iodosuccinimide
CAS Registry Number: 516-12-1
Synonyms: Succiniodimide; NIS
Molecular Formula: C4H4INO2
Molecular Weight: 224.98
Percent Composition: C 21.35%, H 1.79%, I 56.41%, N 6.23%, O 14.22%
Literature References: Prepd by iodination of silver succinimide: Djerassi, Lenk, J. Am. Chem. Soc. 75, 3493 (1953). Structural studies: K. Padmanabhan et al., Acta Crystallogr. C46, 88 (1990). Use as synthetic reagent for cysteine peptides: H. Shih, J. Org. Chem. 58, 3003 (1993); in oxidation and halogenation reactions: A. Speicher, T. Eicher, J. Prakt. Chem. 340, 278 (1998).
Properties: Needles from dioxane + carbon tetrachloride. mp 200-201°. Sol in acetone, methanol; moderately sol in dioxane. Practically insol in CCl4, ether. Dec in water. Protect from light.
Melting point: mp 200-201°
CAUTION: Avoid contact with skin and mucous membranes.
Use: Iodination of ketones and aldehydes.