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CAS No 518-34-3 , D-Tetrandrine

  • Name: D-Tetrandrine
  • Synonyms: Hanfangchin A; (+)-Tetrandrine;D-Tetrandrine; (S,S)-Tetrandrine; Tetrandrin; Sinomenine A; 518-34-3; Fanchinine;
  • CAS Registry Number:
  • Melting Point: 219-222 ºC
  • Density: 1.17 g/cm3 (20 C)
  • Refractive index: 1.585
  • Alpha: 285 º (C=1, CHCL3)
  • Safety Statements: Poison by intraperitoneal route. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
  • Hazard Symbols: Xi
  • Molecular Weight: 622.74988
  • InchiKey: WVTKBKWTSCPRNU-KYJUHHDHSA-N
  • InChI: InChI=1S/C38H42N2O6/c1-39-15-13-25-20-32(42-4)34-22-28(25)29(39)17-23-7-
    10-27(11-8-23)45-33-19-24(9-12-31(33)41-3)18-30-36-26(14-16-40(30)2)21-
    35(43-5)37(44-6)38(36)46-34/h7-12,19-22,29-30H,13-18H2,1-6H3/t29-,
    30-/m0/s1
  • Risk Statements: S22;S24/25
  • Molecular Formula: C38H42N2O6
  • Molecular Structure:CAS No:518-34-3 D-Tetrandrine

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References of D-Tetrandrine
Title: Tetrandrine
CAS Registry Number: 518-34-3
CAS Name: (1b)-6,6￠,7,12-Tetramethoxy-2,2￠-dimethylberbaman
Molecular Formula: C38H42N2O6
Molecular Weight: 622.75
Percent Composition: C 73.29%, H 6.80%, N 4.50%, O 15.41%
Literature References: From root of Stephania tetrandra S. Moore, Menispermaceae. Isoln: Kondo, Yano, Ann. 497, 90 (1932). Structure: Fujita, Murai, J. Pharm. Soc. Jpn. 71, 1039 (1951). Synthesis: Kataoka, C.A. 51, 16501i (1957). Total synthesis: Inubushi et al., Tetrahedron Lett. 1968, 3399; eidem, J. Chem. Soc. C 1969, 1547. Present in the Chinese drug han-fang-chi.
Properties: Needles. mp 217-218°. [a]D26 +252.4° (chloroform). Practically insol in water, petr ether; sol in ether and some other organic solvents.
Melting point: mp 217-218°
Optical Rotation: [a]D26 +252.4° (chloroform)
 
Derivative Type: l-Form
CAS Registry Number: 1263-79-2
Synonyms: Phaenthine
Properties: mp 210°. [a]D20 -278° (chloroform).
Melting point: mp 210°
Optical Rotation: [a]D20 -278° (chloroform)
 
Therap-Cat: Analgesic; antipyretic.
Keywords: Analgesic (Non-Narcotic); Antipyretic.