Home > Name List By other > (8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15, 16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol

CAS No 52-76-6 , (8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,
16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol

  • Name: (8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,
    16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol
  • Synonyms: Exlutona;Ethinylestrenol; Exlution; Endometril; Orgametil;(8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,
    16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol; Exluton; Linestrenol; Ethynylestrenol; Lynoestrenol;
  • CAS Registry Number:
  • Melting Point: 158 ºC
  • Density: 1.08 g/cm3
  • Refractive index: 1.567
  • Safety Statements: An experimental teratogen. Experimental reproductive effects. Human reproductive effects by ingestion and implant routes: menstrual cycle changes or disorders, female fertility index, other fertility changes and effects on females. Questionable carcinogen. Used in oral contraceptives and in the treatment of dysfunctional uterine bleeding. When heated to decomposition it emits acrid smoke and irritating fumes.
  • EINECS: 200-151-4
  • Molecular Weight: 284.43572
  • InchiKey: YNVGQYHLRCDXFQ-XGXHKTLJSA-N
  • InChI: InChI=1S/C20H28O/c1-3-20(21)13-11-18-17-9-8-14-6-4-5-7-15(14)16(17)10-
    12-19(18,20)2/h1,6,15-18,21H,4-5,7-13H2,2H3/t15-,16+,17+,18-,19-,
    20-/m0/s1
  • Molecular Formula: C20H28O
  • Molecular Structure:CAS No:52-76-6 (8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,<br />16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol

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52-76-6 MESTEROLONE ENTERPRISE STANDARD

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References of (8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,
16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol
Title: Lynestrenol
CAS Registry Number: 52-76-6
CAS Name: (17a)-19-Norpregn-4-en-20-yn-17-ol
Synonyms: 17a-ethinyl-17b-hydroxyestr-4-ene; 17a-ethynylestr-4-en-17b-ol; 3-desoxynorlutin; ethinylestrenol
Trademarks: Exluton(a) (Organon); Exlutena (Organon); Orgametril (Organon); Orgametil
Molecular Formula: C20H28O
Molecular Weight: 284.44
Percent Composition: C 84.45%, H 9.92%, O 5.62%
Literature References: Prepn: de Winter et al., Chem. Ind. (London) 1959, 905. Metabolism: Kamyab et al., Biochem. J. 103, 14P (1967); J. Endocrinol. 42, 337 (1968). Pharmacokinetics and metabolism: H. Kuhl et al., Contraception 26, 303 (1982). Clinical trial of use in normophasic oral contraceptives: N. Dombrowicz et al., ibid. 22, 537 (1980). Review of carcinogenicity studies: IARC Monographs 21, 407-415 (1979).
Properties: Solid, mp 158-160°. [a]D -13° (chloroform).
Melting point: mp 158-160°
Optical Rotation: [a]D -13° (chloroform)
 
Derivative Type: Mixture with ethinyl estradiol
CAS Registry Number: 8064-76-4
Trademarks: Fysionorm (Nourypharma); Minilyn (Organon); Ovanon (Nourypharma); Ovoresta (Organon); Yermonil (Novartis)
 
Derivative Type: Mixture with mestranol
CAS Registry Number: 8015-14-3
Trademarks: Lyndiol (Organon)
 
Therap-Cat: Progestogen. In combination with estrogen as oral contraceptive.
Keywords: Contraceptive (Oral); Progestogen.