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CAS No 52549-17-4 , 2-(5H-chromeno[2,3-b]pyridin-7-yl)propanoic acid

  • Name: 2-(5H-chromeno[2,3-b]pyridin-7-yl)propanoic acid
  • Synonyms: Pranoprofeno [INN-Spanish]; Pranoprofene [INN-French];pranoprofen; 52549-17-4; Niflan;2-(5H-chromeno[2,3-b]pyridin-7-yl)propanoic acid; Pranoprofenum [INN-Latin]; Y-8004; pyranoprofen;
  • CAS Registry Number:
  • Flash Point: 465.7 °C at 760 mmHg
  • Boiling Point: 465.7 °C at 760 mmHg
  • Density: 1.308 g/cm3
  • Refractive index: 1.628
  • Safety Statements: Poison by ingestion, subcutaneous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: 465.7 °C at 760 mmHg
  • Molecular Weight: 255.26862
  • InchiKey: TVQZAMVBTVNYLA-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H13NO3/c1-9(15(17)18)10-4-5-13-12(7-10)8-11-3-2-6-16-14(11)
    19-13/h2-7,9H,8H2,1H3,(H,17,18)
  • Molecular Formula: C15H13NO3
  • Molecular Structure:CAS No:52549-17-4 2-(5H-chromeno[2,3-b]pyridin-7-yl)propanoic acid

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52549-17-4 PRANOPROFEN

  • China NINGBO V&P CHEMISTRY [Manufacturer]
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52549-17-4 Pranoprofen

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52549-17-4 Pranoprofen

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References of 2-(5H-chromeno[2,3-b]pyridin-7-yl)propanoic acid
Title: Pranoprofen
CAS Registry Number: 52549-17-4
CAS Name: a-Methyl-5H-[1]benzopyrano[2,3-b]pyridine-7-acetic acid
Synonyms: 2-(5H-[1]benzopyrano[2,3-b]pyridin-7-yl)propionic acid
Manufacturers' Codes: Y-8004
Trademarks: Niflan (Yoshitomi)
Molecular Formula: C15H13NO3
Molecular Weight: 255.27
Percent Composition: C 70.58%, H 5.13%, N 5.49%, O 18.80%
Literature References: Prepn: M. Nakanishi et al., DE 2337052; eidem, US 3931205 (1974, 1976 both to Yoshitomi); eidem, Yakugaku Zasshi 96, 99 (1976), C.A. 84, 135515b (1976). Physicochemical properties: M. Nobutoki, Y. Ota, Iyakuhin Kenkyu 7, 200 (1976), C.A. 88, 110468h (1978). Absorption, metabolism, distribution, excretion: Y. Kato et al., Yakuri to Chiryo 4, 1473 (1976), C.A. 88, 130710j (1978). Pharmacological study: Y. Maruyama et al., Nippon Yakurigaku Zasshi 73, 113 (1977), C.A. 88, 276m (1978). Toxicity study: M. Edanaga et al., Iyakuhin Kenkyu 7, 211 (1976), C.A. 88, 131015y (1978).
Properties: Cryst from aq dioxane, mp 182-183°. LD50 in male mice, rats (mg/kg): 447.3, 87.3 orally (Edanaga).
Melting point: mp 182-183°
Toxicity data: LD50 in male mice, rats (mg/kg): 447.3, 87.3 orally (Edanaga)
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Arylpropionic Acid Derivatives.