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CAS No 52809-07-1 , L-Quisqualic acid Search by region : China

  • Name: L-Quisqualic acid
  • Synonyms: S-Quisqualic acid; Quisqualinic acid;1,2,4-Oxadiazolidine-2-propanoicacid, a-amino-3,5-dioxo-, (S)-;Quisqualic acid (7CI); L-Quisqualic acid;L-Quisqualic acid;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.679g/cm3
  • Refractive index: 1.571
  • Safety Statements: 26-36
  • Hazard Symbols: Xn
  • Flash Point: °C
  • Molecular Weight: 189.13
  • InChI: InChI=1/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1
  • Risk Statements: 20/21/22
  • Molecular Formula: C5H7N3O5
  • Molecular Structure:CAS No:52809-07-1 L-Quisqualic acid

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52809-07-1 1,2,4-Oxadiazolidine-2-propanoicacid, a-amino-3,5-dioxo-, (aS)-

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52809-07-1 (+)-QUISQUALIC ACID

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References of L-Quisqualic acid
Title: Quisqualic Acid
CAS Registry Number: 52809-07-1
CAS Name: (aS)-a-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid
Synonyms: L-quisqualic acid; b-(3,5-dioxo-1,2,4-oxodiazolidin-2-yl)-L-alanine
Molecular Formula: C5H7N3O5
Molecular Weight: 189.13
Percent Composition: C 31.75%, H 3.73%, N 22.22%, O 42.30%
Literature References: Excitatory amino acid (EAA) used to identify a specific subset of EAA receptors; consequently, the receptors are known as quisqualate receptors. See also NMDA, kainic acid. Isoln from the seeds of Quisqualis chinesis and anthelmintic activity: Y.-C. Tuan et al., Yao Hsueh Hsueh Pao 5, 87 (1957), C.A. 56, 14896b (1958); from Q. indica: S.-T. Fang, J.-H. Chu, Hua Hsueh Hsueh Pao 30, 226 (1964), C.A. 61, 7359f (1962); from Q. fructus: T. Takemoto et al., Yakugaku Zasshi 95, 176 (1975), C.A. 82, 152211a (1975). Enzymic synthesis: I. Murakoshi et al., Chem. Pharm. Bull. 22, 473 (1974). Total synthesis: J. E. Baldwin et al., Chem. Commun. 1985, 256. Crystal structure: J. L. Flippen, R. D. Gilardi, Acta Crystallogr. B32, 951 (1976). Identification as a neuroexcitant: H. Shinozaki, I. Shibuya, Neuropharmacology 13, 665 (1974). Receptor binding studies: K. Koshiya, Life Sci. 37, 1373 (1985); J. T. Greenamyre, J. Pharmacol. Exp. Ther. 233, 254 (1985). Review of isolation of quisqualic acid and other EAAs: T. Takemoto, in Kainic Acid as a Tool in Neurobiology, R. G. McGeer et al., Eds. (Raven Press, New York, 1978) pp 1-15.
Properties: Crystals from water-ethanol, mp 190-191°. [a]D20 +17.0° (c = 2.0 in 6M HCl).
Melting point: mp 190-191°
Optical Rotation: [a]D20 +17.0° (c = 2.0 in 6M HCl)