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CAS No 53-03-2 , (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,
13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,
11-dione

  • Name: (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,
    13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,
    11-dione
  • Synonyms: Encorton; Decortisyl; Dehydrocortisone;Deltasone; Dacortin; Orasone; Decortin; Meticorten; Deltacortisone;(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,
    13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,
    11-dione;
  • CAS Registry Number:
  • Transport: 25kgs
  • Melting Point: 233-235 ºC (DEC.)
  • Flash Point: 314.8°C
  • Boiling Point: 573.7°Cat760mmHg
  • Density: 1.3g/cm3
  • Refractive index: 170 ° (C=0.5, Dioxane)
  • Alpha: 169 º (C=0.5, DIOXANE)
  • Water Solubility: Slightly soluble
  • Safety Statements: R63
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 314.8°C
  • EINECS: 200-160-3
  • Molecular Weight: 358.42814
  • InchiKey: XOFYZVNMUHMLCC-ZPOLXVRWSA-N
  • InChI: InChI=1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,
    17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,
    10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
  • Risk Statements: S36/37/39;S45
  • Molecular Formula: C21H26O5
  • Molecular Structure:CAS No:53-03-2 (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,<br />13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,<br />11-dione

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53-03-2 PREDNISONE

  • China Suntin MediPharma Co. Ltd. [Importer/Exporter]
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  • China orichem international ltd [Manufacturers]
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53-03-2 prednisone

  • prednisone
  • China Daming Ruiheng Chemical Co. LTD [Manufacturer]
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References of (8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,
13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,
11-dione
Title: Prednisone
CAS Registry Number: 53-03-2
CAS Name: 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
Synonyms: 1,4-pregnadiene-17a,21-diol-3,11,20-trione; D1-dehydrocortisone; D1-cortisone; deltacortisone; delta E; metacortandracin; retrocortine
Manufacturers' Codes: NSC-10023
Trademarks: Colisone (Frosst); Cortancyl (Aventis); Dacortin (Merck KGaA); Decortin (Merck KGaA); Deltacortene (Bruno); Deltacortone (Merck & Co.); Deltasone (Upjohn); Deltison (Ferring); Di-Adreson (Organon); Encorton (Polfa); Hostacortin (Hoechst); Meticorten (Schering-Plough); Orasone (Solvay); Rectodelt (Trommsdorff); Sone (Fawns & McAllan); Ultracorten (Novartis)
Molecular Formula: C21H26O5
Molecular Weight: 358.43
Percent Composition: C 70.37%, H 7.31%, O 22.32%
Literature References: Prepn: Oliveto, Gould, US 2897216 (1959 to Schering). Microbiological prepn: Nobile et al., J. Am. Chem. Soc. 77, 4184 (1955); Nobile, US 2837464 and US 3134718 (1958, 1964 both to Schering); Herzog et al., Tetrahedron 18, 581 (1962). Structure: Herzog et al., Science 121, 176 (1955); cf. Djerassi et al., US 2579479 (1951 to Syntex).
Properties: Crystals, dec 233-235°. [a]D25 +172° (dioxane). uv max (methanol): 238 nm (e 15500). Very slightly sol in water. One gram dissolves in about 150 ml alcohol, in about 200 ml chloroform. Slightly sol in methanol, dioxane.
Optical Rotation: [a]D25 +172° (dioxane)
Absorption maximum: uv max (methanol): 238 nm (e 15500)
 
Derivative Type: 21-Acetate
CAS Registry Number: 125-10-0
Molecular Formula: C23H28O6
Molecular Weight: 400.46
Percent Composition: C 68.98%, H 7.05%, O 23.97%
Properties: Crystals, dec 226-232°. [a]D25 +186° (dioxane). uv max (ethanol): 238 nm (e 16100).
Optical Rotation: [a]D25 +186° (dioxane)
Absorption maximum: uv max (ethanol): 238 nm (e 16100)
 
Therap-Cat: Glucocorticoid.
Therap-Cat-Vet: Adrenocortical steroid. Glucocorticoid, anti-inflammatory.
Keywords: Glucocorticoid.