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CAS No 53016-31-2 , NORELGESTROMIN Search by region : India

  • Name: NORELGESTROMIN
  • Synonyms: 18-Methylnorethindrone oxime ; Levonorgestrel 3-oxime ; D-Norgestrel 3-oxime ;(17a)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one Oxime ;NORELGESTROMIN; BRN 4202099 ;
  • CAS Registry Number:
  • Flash Point: 327.1°C
  • Boiling Point: 491.9°Cat760mmHg
  • Density: 1.23g/cm3
  • Refractive index: 1.633
  • Flash Point: 327.1°C
  • Molecular Weight: 327.465
  • InChI: InChI=1/C21H29NO2/c1-3-20-11-9-17-16-8-6-15(22-24)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23-24H,3,5-12H2,1H3/b22-15+/t16-,17+,18+,19-,20-,21-/m0/s1
  • Molecular Formula: C21H29NO2
  • Molecular Structure:CAS No:53016-31-2 NORELGESTROMIN

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53016-31-2 17-DESACETYL NORGESTIMATE-D6

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References of NORELGESTROMIN
Title: Norelgestromin
CAS Registry Number: 53016-31-2
CAS Name: (17a)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one oxime
Synonyms: 17-deacetylnorgestimate; 18-methylnorethindrone oxime; levonorgestrel 3-oxime
Manufacturers' Codes: RWJ-10553
Molecular Formula: C21H29NO2
Molecular Weight: 327.46
Percent Composition: C 77.02%, H 8.93%, N 4.28%, O 9.77%
Literature References: Bioactive metabolite of norgestimate, q.v. Prepd as intermediate of norgestrel, q.v.: NL 7306609 (1973 to Richter Gedeon). Prepn and identification as norgestimate metabolite: S. F. Sisenwine et al., Contraception 15, 25 (1977). Pharmacology: J. L. McGuire et al., Am. J. Obstet. Gynecol. 163, 2127 (1990). Use as contraceptive patch: J. Jona et al., WO 9640355; eidem, US 5876746 (1996, 1999 both to Cygnus). Clinical pharmacokinetics: L. S. Abrams et al., Br. J. Clin. Pharmacol. 53, 141 (2002). Review of clinical pharmacology and efficacy: R. T. Burkman, Int. J. Fertil. 47, 69-76 (2002); B. L. Sicat, Pharmacotherapy 23, 472-480 (2003).
Properties: Crystals, mp 112°.
Melting point: mp 112°
 
Derivative Type: Combination with ethinyl estradiol
CAS Registry Number: 396715-57-4
Trademarks: Evra (Janssen-Cilag); Ortho Evra (Ortho)
 
Therap-Cat: Progestogen; in combination with estrogen as transdermal contraceptive.
Keywords: Progestogen; Contraceptive (Transdermal).