Home > Name List By other > (8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-1,2,3,6,7,8, 9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-...

CAS No 54024-22-5 , (8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-1,2,3,6,7,8,
9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol

  • Name: (8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-1,2,3,6,7,8,
    9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol
  • Synonyms: ORG 2969; Org-2969; Cyclessa; Kariva;Cerazette; Desogestrelum [INN-Latin]; desogen; Mircette; Desogestrelum;(8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-1,2,3,6,7,8,
    9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol;
  • CAS Registry Number:
  • Melting Point: 109-110 ºC
  • Flash Point: 187.9 ºC
  • Boiling Point: 428.3 ºC at 760 mmHg
  • Density: 1.07 g/cm3
  • Refractive index: 1.566
  • Water Solubility: practically insoluble
  • Safety Statements: Human reproductive effects by ingestion: changes in menstrual cycle and female fertility. Experimental reproductive effects. A steroid. When heated to decomposition it emits acrid smoke and fumes.
  • Flash Point: 187.9 ºC
  • EINECS: 258-929-4
  • Molecular Weight: 310.473
  • InchiKey: RPLCPCMSCLEKRS-BPIQYHPVSA-N
  • InChI: InChI=1S/C22H30O/c1-4-21-14-15(3)20-17-9-7-6-8-16(17)10-11-18(20)19(21)
    12-13-22(21,23)5-2/h2,8,17-20,23H,3-4,6-7,9-14H2,1H3/t17-,18-,19-,20+,
    21-,22-/m0/s1
  • Molecular Formula: C22H30O
  • Molecular Structure:CAS No:54024-22-5 (8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-1,2,3,6,7,8,<br />9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol

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54024-22-5 Desogestrel BP

  • China SNC International Co., Ltd. [Distributor/Wholesaler]
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  • Address: Room No. 711, Minmetals Building, No. 47, Xiangjiang Road, Hexi District, Tianjin 300210, null,TianjinChina
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54024-22-5 Desogestrel

  • China Sinosource Pharma Limited [Importer/Exporter]
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54024-22-5 DESOGESTREL

  • China CHINA CHEM SOURCE (HK) CO.,LTD. [Manufacturer]
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  • Address: CHINA CHEM SOURCE (HK) CO.,LTD.
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54024-22-5 Desogestrel

  • China Emerald-Shanghai Incorporation [Importer/Exporter]
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  • Address: Dong Fang Road 2851 Lane 22-1202, Shanghai, Shanghai,ShanghaiChina
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54024-22-5 Desogestrel

  • China SOGA ENTERPRISES ASIA GROUP [Manufacturers]
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  • Address: No.1,Huanghai Yilu.Rizhao,Shandong null,ShandongChina
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54024-22-5 Desogestrel

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54024-22-5 Desogestrel

  • China Hubei Gedian Humanwell Pharmaceutical Co., Ltd. [Manufacturers]
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54024-22-5 Desogestrel

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54024-22-5 Desogestrel

  • Chemical name: 13-Ethyl-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-17-ol Molecular Structure: Molecular Formula:C22H30O Molecular Weight:310.48 CAS NO.:54024-22-5 Important Specifications: Standard: EP5.0 or In-house Standard Appearance:white ...
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54024-22-5 Desogestrel

  • China Biosyn Healthy Pharma Co.,Ltd. null
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References of (8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-1,2,3,6,7,8,
9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol
Title: Desogestrel
CAS Registry Number: 54024-22-5
CAS Name: (17a)-13-Ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-ol
Synonyms: 17a-ethynyl-18-methyl-11-methylene-D4-estren-17b-ol
Manufacturers' Codes: Org-2969
Trademarks: Cerazette (Organon)
Molecular Formula: C22H30O
Molecular Weight: 310.47
Percent Composition: C 85.11%, H 9.74%, O 5.15%
Literature References: Progestogen with low androgenic potency. Prepn: A. J. van den Broek, DE 2361120; idem, US 3927046 (1974, 1975 both to Akzo); A. J. van den Broek et al., Rec. Trav. Chim. 94, 36 (1975). Biological effects: L. Viinikka et al., Acta Endocrinol. 83, 429 (1976). Endocrinological studies in animals: J. van der Vies, J. de Visser, Arzneim.-Forsch. 33, 231 (1983). Radioimmunoassay: L. Viinikka, J. Steroid Biochem. 9, 979 (1978). Metabolism, pharmacokinetics in humans: L. Viinikka et al., Eur. J. Clin. Pharmacol. 15, 349 (1979). Receptor binding study: E. W. Bergink et al., J. Steroid Biochem. 14, 175 (1981). Clinical trial in combination with ethinyl estradiol: M. J. Weijers, Clin. Ther. 4, 359 (1982); as progestogen-only contraceptive: T. Korver et al., Eur. J. Contracept. Reprod. Health Care 3, 169 (1998).
Properties: Crystals, mp 109-110°. [a]D20 +55° (chloroform).
Melting point: mp 109-110°
Optical Rotation: [a]D20 +55° (chloroform)
 
Derivative Type: Mixture with ethinyl estradiol
CAS Registry Number: 71138-35-7
Trademarks: Cyclosa (Nourypharma); Desogen (Organon); Dicromil (Organon); Marvelon 150/30 (Akzo); Mercilon (Organon); Ortho-Cept (Ortho); Oviol (Nourypharma); Varnoline (Organon)
 
Therap-Cat: Progestogen. Alone or in combination with estrogen as oral contraceptive.
Keywords: Contraceptive (Oral); Progestogen.