Home > Name List By other > (2-chlorophenyl)-[2-[2-(diethylaminomethyl)imidazol-1-yl]-5-nitrophenyl] methanone

CAS No 54533-85-6 , (2-chlorophenyl)-[2-[2-(diethylaminomethyl)imidazol-1-yl]-5-nitrophenyl]
methanone

  • Name: (2-chlorophenyl)-[2-[2-(diethylaminomethyl)imidazol-1-yl]-5-nitrophenyl]
    methanone
  • Synonyms: NCGC00183104-01; Nizofenone [INN]; Nizofenone (INN); 54533-85-6;Nizofenonum [INN-Latin];(2-chlorophenyl)-[2-[2-(diethylaminomethyl)imidazol-1-yl]-5-nitrophenyl]
    methanone; Nizofenona [INN-Spanish]; Y 9179;
  • CAS Registry Number:
  • Density: 1.28 g/cm3
  • Refractive index: 1.623
  • Molecular Weight: 412.86944
  • InchiKey: WZGBZLHGOVJDET-UHFFFAOYSA-N
  • InChI: InChI=1S/C21H21ClN4O3/c1-3-24(4-2)14-20-23-11-12-25(20)19-10-9-15(26(28)
    29)13-17(19)21(27)16-7-5-6-8-18(16)22/h5-13H,3-4,14H2,1-2H3
  • Molecular Formula: C21H21ClN4O3
  • Molecular Structure:CAS No:54533-85-6 (2-chlorophenyl)-[2-[2-(diethylaminomethyl)imidazol-1-yl]-5-nitrophenyl]<br />methanone
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54533-85-6 Methanone,(2-chlorophenyl)[2-[2-[(diethylamino)methyl]-1H-imidazol-1-yl]-5-nitrophenyl]-

  • China Ganolix Pharm Co.,Ltd [Manufacturers]
  • Tel: 86-21-51696579
  • Fax: 86-21-51687927
  • Address: 17301 No 431 Lianhua South Road Minhang District Shanghai 201100 China. Shanghai,ShanghaiChina
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54533-85-6 NIZOFENONE FUMARATE

  • China Shanghai DND Pharm-Technology Co., Inc. [Manufacturer]
  • Tel: 86-21-58783620 (DL)/ 86-21-58783570 EX 8008
  • Fax: 86-21-58783570,58783572,58783595 EX 8003
  • Address: No.2-18A,Lane 85,
    Rongcheng Road,
    Pudong,Shanghai,
    200120 P.R.China null,nullChina
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References of (2-chlorophenyl)-[2-[2-(diethylaminomethyl)imidazol-1-yl]-5-nitrophenyl]
methanone
Title: Nizofenone
CAS Registry Number: 54533-85-6
CAS Name: (2-Chlorophenyl)[2-[2-[(diethylamino)methyl]-1H-imidazol-1-yl]-5-nitrophenyl]methanone
Synonyms: 2¢-chloro-2-[2-[(diethylamino)methyl]imidazol-1-yl]-5-nitrobenzophenone; 1-[2-(2-chlorobenzoyl)-4-nitrophenyl]-2-(diethylaminomethyl)imidazole
Molecular Formula: C21H21ClN4O3
Molecular Weight: 412.87
Percent Composition: C 61.09%, H 5.13%, Cl 8.59%, N 13.57%, O 11.63%
Literature References: Imidazole derivative exhibiting protective activity against cerebral anoxia or ischemia. Prepn: M. Nakanishi et al., DE 2403416; eidem, US 3915981 (1974, 1975 both to Yoshitomi). Antianoxic effect in animal models: H. Yasuda et al., Arch. Int. Pharmacodyn. 233, 136 (1978). Mechanism of action: eidem, ibid. 242, 77 (1979). Multicenter clinical studies: I. Saito et al., Neurol. Res. 5, 29 (1983); T. Ohta et al., J. Neurosurg. 64, 420 (1986). Toxicity studies: H. Horizoe et al., Oyo Yakuri 30, 627 (1985), C.A. 104, 61754m (1986); K. Okumura et al., ibid. 633, C.A. 104, 61755 (1986).
Properties: Pale yellow crystals from isopropyl ether, mp 75-76°.
Melting point: mp 75-76°
 
Derivative Type: Fumarate
CAS Registry Number: 54533-86-7
Synonyms: Midafenone
Manufacturers' Codes: Y-9179
Trademarks: Ekonal (Yoshitomi)
Molecular Formula: C21H21ClN4O3.C4H4O4
Molecular Weight: 528.94
Percent Composition: C 56.77%, H 4.76%, Cl 6.70%, N 10.59%, O 21.17%
Properties: Pale yellow crystals from isopropyl ether, mp 157-158°. LD50 in male, female mice, male, female rats (mg/kg): 495, 504, 1711, 1580 orally; 62, 70, 63, 65 i.v.; 270, 278, 1830, 1629 s.c. (Horizoe).
Melting point: mp 157-158°
Toxicity data: LD50 in male, female mice, male, female rats (mg/kg): 495, 504, 1711, 1580 orally; 62, 70, 63, 65 i.v.; 270, 278, 1830, 1629 s.c. (Horizoe)
 
Therap-Cat: Nootropic.
Keywords: Nootropic.