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CAS No 54965-21-8 , methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate

  • Name: methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate
  • Synonyms: Metiazol; Proftril; Bilutac;Valbazen; Zentel; 54965-21-8;methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate; Eskazole; Albenza; Albendazol;
  • CAS Registry Number:
  • Density: 1.3 g/cm3
  • Refractive index: 1.634
  • Safety Statements: R36/37/38,R61,
  • Hazard Symbols: T:Toxic;
  • HS Code: 29332990
  • EINECS: 259-414-7
  • Molecular Weight: 265.3314
  • InchiKey: HXHWSAZORRCQMX-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/
    h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
  • Risk Statements: S26,S37/39,S45,S53,
  • Molecular Formula: C12H15N3O2S
  • Molecular Structure:CAS No:54965-21-8 methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate

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  • Name: Albendazole (Molecular formula:) C12H15N3O2S (Molecular weight:) 265.33 CAS NO.: 54965-21-8 Appearance: White needle crystal or powder Use: Albendazole is a broad-spectrum anthelmintic for humans and animals Standard: USP/BP/CP Package:25kg/Dru...
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References of methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate
Title: Albendazole
CAS Registry Number: 54965-21-8
CAS Name: [5-(Propylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester
Synonyms: methyl 5-(propylthio)-2-benzimidazolecarbamate; 5-(propylthio)-2-carbomethoxyaminobenzimidazole
Manufacturers' Codes: SKF-62979
Trademarks: Albenza (GSK); Eskazole (GSK); Valbazen (Pfizer); Zentel (GSK)
Molecular Formula: C12H15N3O2S
Molecular Weight: 265.33
Percent Composition: C 54.32%, H 5.70%, N 15.84%, O 12.06%, S 12.08%
Literature References: Prepn: R. J. Gyurik, V. J. Theodorides, US 3915986 (1975 to SmithKline). Anthelmintic spectrum: V. J. Theodorides, Experientia 32, 702 (1976). Metabolism: R. J. Gyurik et al., Drug Metab. Dispos. 9, 503 (1981). Efficacy in cattle vs gastrointestinal parasites: J. C. Williams et al., Am. J. Vet. Res. 38, 2037 (1977); vs liver flukes: T. M. Craig et al., ibid. 53, 1170 (1992). Clinical trial in mixed helminth infections: P. Pene et al., Am. J. Trop. Med. Hyg. 31, 263 (1982); in echinococcosis: R. J. Horton, Trans. R. Soc. Trop. Med. Hyg. 83, 97 (1989).
Properties: Colorless crystals, mp 208-210°. Sol in DMSO, strong acids, strong bases; slightly sol in methanol, chloroform, ethyl acetate, acetonitrile. Practically insol in water.
Melting point: mp 208-210°
 
Derivative Type: Sulfoxide
CAS Registry Number: 54029-12-8
Synonyms: Albendazole oxide; ricobendazole; rycobendazole
Manufacturers' Codes: RS-8852
Trademarks: Rycoben (Novartis)
Molecular Formula: C12H15N3O3S
Molecular Weight: 281.33
Percent Composition: C 51.23%, H 5.37%, N 14.94%, O 17.06%, S 11.40%
Literature References: Active metabolite of albendazole. Bioavailability: L. Dominguez et al., Farmaco 50, 697 (1995).
Properties: mp 226-228° (dec).
Melting point: mp 226-228° (dec)
 
Therap-Cat: Anthelmintic (Cestodes).
Therap-Cat-Vet: Anthelmintic.
Keywords: Anthelmintic (Cestodes).