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CAS No 55-56-1 , (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]
methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine

  • Name: (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]
    methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine
  • Synonyms: Hexadol; Soretol;Tubulicid; Rotersept; Nolvasan;(1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]
    methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine; Fimeil; Peridex; Sterilon; Hibiclens;
  • CAS Registry Number:
  • Transport: UN 3077
  • Melting Point: 132-136 ºC
  • Flash Point: 312
  • Boiling Point:
    Vapour density:
  • Density: 1.39 g/cm3
  • Water Solubility: 0.08 G/100 ML (20 ºC)
  • Safety Statements: R36/37/38;R51/53
  • Hazard Symbols: N: Dangerous for the environment;Xi: Irritant;
  • Flash Point: 312
  • EINECS: 200-238-7
  • Molecular Weight: 505.4466
  • InchiKey: GHXZTYHSJHQHIJ-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-
    2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,
    (H5,25,27,29,31,33)(H5,26,28,30,32,34)
  • Risk Statements: S26;S36/37;S60;S61
  • Molecular Formula: C22H30Cl2N10
  • Molecular Structure:CAS No:55-56-1 (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]<br />methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine
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55-56-1 Chlorhexidine Base

  • United States Parchem Trading [Manufacturer]
  • Tel: 914.654.6800
  • Fax: 914.654.6899
  • Address: Parchem Trading Ltd.
    415 Huguenot Street
    New Rochelle, NY 10801 null,nullUnited States
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55-56-1 Chlorhexidine Base

  • India Shreeji Pharma International [Manufacturers]
  • Tel: +91-265-3019110
  • Fax: +91-265-2465036
  • Address: FF/10, Narsinghdham Complex, Sangam Chararasta, Harni Road, Vadodara, Gujarat 390018, Vadodara,GujaratIndia
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55-56-1 Chlorhexidine

  • United States CBSCHEM LIMITED null
  • Fax: (888) 557-9843
  • Address: 621 South 48th Street, Suite 115,Tempe, AZ 85281 null,nullUnited States
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55-56-1 Chlorhexidine

  • China Qingdao Chinaoil Co., Ltd null
  • Fax: +86-532-85713888 85723888
  • Address: 22/F,Golden Light Tower,No.56, Xianggang Zhong Road, Qingdao 266071, China null,nullChina
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55-56-1 CHLORHEXIDINE

  • China Shanghai Sunwise Chemical Co., Ltd. [Manufacturer]
  • Tel: +86-21-64063188
  • Fax: +86-21-64062858
  • Address: Shanghai Sunwise Chemical Co., Ltd.
    7G, No 1235 Wuzhong Road
    Shanghai P.R.China null,nullChina
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55-56-1 Chlorhexidine Hydrochloride

  • Chlorhexidine Hydrochloride, BP
  • India J.INC. [Manufacturer]
  • Tel: +91 79 30071152, 30071190, 30071175, 30071153
  • Fax: +91 79 30071176, 26574630
  • Address: # 95, Rangwala Towers, Law garden, Ellisbridge, Ahmedabad 380006, Gujarat State, India. 380006 AhmedabadINDIA Ahmedabad,nullIndia
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55-56-1 Chlorhexidine Hydrochloride

  • Chlorhexidine Hydrochloride, 98%min
  • China Shanghai Everchem Co.,Ltd. [Manufacturer]
  • Tel: +86-21-5192-3949
  • Fax: +86-21-5192-3940
  • Address: No.277 Zheqiao Road,
    Shanghai 201206 China null,nullChina
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55-56-1 CHLOR HEXIDINE

  • India JAI RADHE SALES [Manufacturer]
  • Tel: +91-79-26431096/ +91-79-65255722
  • Fax: +91-79-26569884
  • Address: JAI RADHE SALES,
    309/310 HARIKRUPA TOWER,
    NR.OLD SHARDA MANDIR CHAR RASTA,
    ELLISBRIDGE, AHMEDABAD-
    380 006 GUJRAT, INDIA null,nullIndia
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55-56-1 Chlorhexidine Base

  • United States Wintersun chemical [Manufacturers]
  • Tel: +1 909 930-1688 0086-574-87322704, 87298453, 27857
  • Fax: +1 909 947-1788
  • Address: null Ontario,OntarioUnited States
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55-56-1 CHLORHEXIDINE BASE

  • United States Dishman USA [Manufacturer]
  • Tel: 732-560-4300
  • Fax: 732-560-4343
  • Address: Dishman USA
    550 Union Ave., Suite 9
    Middlesex, NJ 08846 null,nullUnited States
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References of (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]
methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine
Title: Chlorhexidine
CAS Registry Number: 55-56-1
CAS Name: N,N¢¢-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide
Synonyms: 1,1¢-hexamethylenebis[5-(p-chlorophenyl)biguanide]; 1,6-bis[N¢-(p-chlorophenyl)-N5-biguanido]hexane; 1,6-bis(N5-p-chlorophenyl-N¢-diguanido)hexane; 1,6-di(4¢-chlorophenyldiguanido)hexane
Manufacturers' Codes: 10040
Molecular Formula: C22H30Cl2N10
Molecular Weight: 505.45
Percent Composition: C 52.28%, H 5.98%, Cl 14.03%, N 27.71%
Literature References: Bisbiguanide with bacteriostatic activity. Prepn: Rose, Swain, J. Chem. Soc. 1956, 4422; eidem, US 2684924 (1954 to I.C.I.). Antibacterial activity and acute toxicity: G. E. Davies et al., Br. J. Pharmacol. 9, 192 (1954). Review of toxicology and clinical uses: D. M. Foulkes, J. Periodontal Res. 8, Suppl. 12, 55-60 (1973). Series of articles on clinical efficacy in gingivitis and plaque control: ibid. 21, Suppl. 16, 1-89 (1986).
Properties: Crystals from methanol, mp 134°. Strong alkaline reaction. Soly in water at 20°: 0.08% (w/v).
Melting point: mp 134°
 
Derivative Type: Dihydrochloride
CAS Registry Number: 3697-42-5
Trademarks: Lisium (Brunton)
Molecular Formula: C22H30Cl2N10.2HCl
Molecular Weight: 578.37
Percent Composition: C 45.69%, H 5.58%, Cl 24.52%, N 24.22%
Properties: Crystals, dec 260-262°. Soly in water at 20°: 0.06 g/100 ml.
 
Derivative Type: Diacetate
CAS Registry Number: 56-95-1
Trademarks: Chlorasept 2000 (Baxter); Nolvasan (Fort Dodge)
Molecular Formula: C22H30Cl2N10.2C2H4O2
Molecular Weight: 625.55
Percent Composition: C 49.92%, H 6.12%, Cl 11.33%, N 22.39%, O 10.23%
Properties: Crystals, mp 154-155°. Neutral reaction. Soly in water at 20°: 1.9 g/100 ml. Aq solns dec when heated above 70°. Soluble in alcohol, glycerol, propylene glycol, polyethylene glycols. LD50 orally in mice: 2 g/kg (Davies).
Melting point: mp 154-155°
Toxicity data: LD50 orally in mice: 2 g/kg (Davies)
 
Derivative Type: D-Digluconate
CAS Registry Number: 18472-51-0
Trademarks: Chlorhexamed (Blendax-Richardson); Bacticlens (Smith & Nephew); Corsodyl (Fink); Gingisan (Chassot); Hibiclens (Zeneca); Hibident (SKB); Hibidil (Zeneca); Hibiscrub (Zeneca); Hibital (Zeneca); Hibitane (Zeneca); Peridex (Procter & Gamble); pHiso-Med; Plac Out (Bernabo); Rotersept (Roterpharma); Secalan (Zyma); Sterilon (Roter); Unisept (Schering)
Properties: Soly in water at 20°: >50% (w/v). LD50 in mice (mg/kg): 22 i.v.; 1800 orally (Foulkes).
Toxicity data: LD50 in mice (mg/kg): 22 i.v.; 1800 orally (Foulkes)
 
Therap-Cat: Antiseptic; disinfectant.
Therap-Cat-Vet: Antiseptic; disinfectant.
Keywords: Antiseptic/Disinfectant; Guanidines.