Home > Name List By other > (2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]disulfanyl]propanoic acid

CAS No 56-89-3 , (2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]disulfanyl]propanoic acid

  • Name: (2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]disulfanyl]propanoic acid
  • Synonyms: L-Cystin; Oxidized L-cysteine; Cysteine disulfide; Cystin;(2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]disulfanyl]propanoic acid; Dicysteine;L-cystine; Cystine acid; L-Dicysteine; beta,beta'-Dithiodialanine;
  • CAS Registry Number:
  • Transport: 25kgs
  • Melting Point: 260-261 ºC
  • Density: 1.68
  • Refractive index: -222.5 ° (C=1, 1mol/L HCl)
  • Alpha: -224 º(C=2 IN 1M HCL)
  • Water Solubility: 0.112 G/L (25 ºC)
  • Safety Statements: 26-36-24/25
  • Hazard Symbols: Xi: Irritant;
  • HS Code: 29309014
  • EINECS: 200-296-3
  • Molecular Weight: 240.30048
  • InchiKey: LEVWYRKDKASIDU-IMJSIDKUSA-N
  • InChI: InChI=1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,
    (H,9,10)(H,11,12)/t3-,4-/m0/s1
  • Risk Statements: S24/25
  • Molecular Formula: C6H12N2O4S2
  • Molecular Structure:CAS No:56-89-3 (2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]disulfanyl]propanoic acid

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References of (2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]disulfanyl]propanoic acid
Title: Cystine
CAS Registry Number: 56-89-3
CAS Name: L-Cystine
Synonyms: [R-(R*,R*)]-3,3￠-dithiobis[2-aminopropanoic acid]; dicysteine; b,b￠-dithiodialanine; a-diamino-b-dithiolactic acid; b,b￠-diamino-b,b￠-dicarboxydiethyl disulfide; bis(b-amino-b-carboxyethyl) disulfide
Trademarks: Gelucystine (Parke-Davis)
Molecular Formula: C6H12N2O4S2
Molecular Weight: 240.30
Percent Composition: C 29.99%, H 5.03%, N 11.66%, O 26.63%, S 26.69%
Literature References: Non-essential amino acid for human development. Formed by the dimerization of two cysteines, q.v. through the sulfur. These disulfide bridges occur both within and between polypeptides; often found in extracellular proteins. First amino acid described in 1810 by Wollaston. Isoln from horn hydrolysate: K. A. H. M?rner, Z. Physiol. Chem. 28, 595 (1899). Early chemistry and biochemistry: Amino Acids and Proteins, D. M. Greenberg, Ed. (Charles C. Thomas, Springfield, IL, 1951) 950 pp. passim; J. P. Greenstein, M. Winitz, Chemistry of the Amino Acids vols 1-3 (John Wiley and Sons, Inc., New York, 1961) pp. 1879-1928, passim. Distribution in protein: R. C. Fahey et al., J. Mol. Evol. 10, 155 (1977). Review of lysosomal transport including pathophysiology: W. Gahl in Pathophysiol. Lysosomal Transp., J. G. Thoene, Ed. (CRC Press, Boca Raton, FL, 1992) pp 45-71. Review of thermodynamics and kinetics: T. R. Ralph et al., J. Electroanal. Chem. 375, 1-15 (1994); of electrosynthesis: eidem, ibid. 17-27.
Properties: Hexagonal tablets from water, dec 260-261° (sealed tube). [a]D20 -223.4° (1.0N HCl). pK1 1; pK2 2.1; pK3 8.02; pK4 8.71 at 35°. Soly in water (g/l) at 25°: 0.112; at 50°: 0.239; at 75°: 0.523; at 100°: 1.142. Quite sol in aq solns below pH 2 or above pH 8. Soly curves: Sano, Biochem. Z. 168, 14 (1926). Insol in alc. Absorption spectrum: Marchlewski, Nowotonowna, Bull. Soc. Chim. Fr. [4] 39, 163, 166 (1926).
pKa: pK1 1; pK2 2.1; pK3 8.02; pK4 8.71 at 35°
Optical Rotation: [a]D20 -223.4° (1.0N HCl)
 
Derivative Type: D-Form
CAS Registry Number: 349-46-2
Properties: Crystals. [a]D20 +223° (1.0N HCl). Soly in water at 25°: 0.057 g/l.
Optical Rotation: [a]D20 +223° (1.0N HCl)
 
Derivative Type: DL-Form
CAS Registry Number: 923-32-0
Properties: Crystals. Soly in water at 25°: 0.057 g/l.
 
Derivative Type: meso-Form
CAS Registry Number: 6020-39-9
Properties: Crystals. Soly in water: 0.056 g/l.