Home > Name List By other > [(4R,4aR,7S,7aR,12bS)-9-acetyloxy-3-methyl-2,4,4a,7,7a, 13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl] acetat...

CAS No 561-27-3 , [(4R,4aR,7S,7aR,12bS)-9-acetyloxy-3-methyl-2,4,4a,7,7a,
13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl] acetate

  • Name: [(4R,4aR,7S,7aR,12bS)-9-acetyloxy-3-methyl-2,4,4a,7,7a,
    13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl] acetate
  • Synonyms: 3,6-Diacetylmorphine; Preza; Diaphorm; Diamorphine; Morphacetin;[(4R,4aR,7S,7aR,12bS)-9-acetyloxy-3-methyl-2,4,4a,7,7a,
    13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl] acetate; Acetomorphine; Smack; Morphine diacetate;Diacetylmorphine;
  • CAS Registry Number:
  • Transport: UN 1544 6.1/PG 1
  • Melting Point: 173 deg C
  • Flash Point: 251.9°C
  • Boiling Point: 492.9°Cat760mmHg
  • Density: 1.34g/cm3
  • Refractive index: 1.629
  • Safety Statements: A poison by ingestion, intracerebral, and subcutaneous routes. The fatal dose is between 1/6 and 2 grains. Human reproductive effects by subcutaneous and intravenous routes: newborn drug dependence. An experimental teratogen. Experimental reproductive effects. Mutation data reported.

    Resembles morphine in its general results, but acts more strongly on the respiration and is therefore more poisonous. Its depressant effects on the cerebrum appear to be greater than those of codeine. Large doses cause excitement and convulsions in animals and humans. The more common symptoms are headache; disturbance of vision; slow, small, regular pulse; restlessness; cramps in the extremities; slight cyanosis; slow, deep respiration and death from respiratory paralysis. A poisonous, habit-forming drug. When heated to decomposition it emits toxic fumes of NOx. See also

  • Hazard Symbols: Addictive narcotic; ingestion of less than 1 grain may be fatal. Cannot be legally sold in U.S.
  • Flash Point: 251.9°C
  • EINECS: 209-217-7
  • Molecular Weight: 369.41102
  • InchiKey: GVGLGOZIDCSQPN-PVHGPHFFSA-N
  • InChI: InChI=1S/C21H23NO5/c1-11(23)25-16-6-4-13-10-15-14-5-7-17(26-12(2)24)20-
    21(14,8-9-22(15)3)18(13)19(16)27-20/h4-7,14-15,17,20H,8-10H2,1-3H3/t14-,
    15+,17-,20-,21-/m0/s1
  • Risk Statements: 26/27/28
  • Molecular Formula: C21H23NO5
  • Molecular Structure:CAS No:561-27-3 [(4R,4aR,7S,7aR,12bS)-9-acetyloxy-3-methyl-2,4,4a,7,7a,<br />13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl] acetate
Search by region :

Select to

561-27-3 Heroin

  • Heroin A narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in ... CAS number 561-27-3. Names: CHEBI:27808
  • Cameroon Mandesto Srl [Manufacturer]
  • Tel: 237-237-76527471
  • Address: Douala Akwa douala,doualaCameroon
Contact Supplier

561-27-3 Heroin

  • Heroin, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
Contact Supplier

561-27-3 HEROIN AND HEROIN HYDROCHLORIDE FOR SALE

  • Looking for serious buyers or importers of Heroin and Heroin hydrochloride If interested contact us or send us an inquiry Thanks for reading
  • United States ABVCo.Ltd [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 1-509-7230092
  • Address: Silver Street laurel,United States
Contact Supplier

561-27-3 Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl- (5a,6a)-, 3,6-diacetate

Contact Supplier

561-27-3 Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl- (5a,6a)-, 3,6-diacetate

Contact Supplier

561-27-3 Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl- (5a,6a)-, 3,6-diacetate

  • Cameroon mukala products limited [Dealer]
  • Tel: 0023795193480
  • Fax: 0023295193480
  • Address: Rue poux douala Douala,LittoralCameroon
Contact Supplier

561-27-3 Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl- (5a,6a)-, 3,6-diacetate

  • Nigeria Spring pharmaceuticals limited [Manufacturers]
  • Tel: +2348027294022
  • Fax: +022005878
  • Address: Spring Pharma Building,46 Kolawole Odutola street Ikeja,lagos stateNigeria
Contact Supplier

561-27-3 Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl- (5a,6a)-, 3,6-diacetate

  • Cameroon pure chemicals [Manufacturers]
  • Tel: 0023774906261
  • Fax: +00237-74906261
  • Address: 223 street Ave Likomba,south west regionCameroon
Contact Supplier

561-27-3 Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl- (5a,6a)-, 3,6-diacetate

  • United Kingdom readychemicals ltd [Distributor/Wholesaler]
  • Tel: +44-789-08765
  • Address: flat 7,23-25 gloucester place, brighton gloucester,east sussexUnited Kingdom
Contact Supplier

Select to

References of [(4R,4aR,7S,7aR,12bS)-9-acetyloxy-3-methyl-2,4,4a,7,7a,
13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl] acetate
Title: Diacetylmorphine
CAS Registry Number: 561-27-3
CAS Name: (5a,6a)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol diacetate (ester)
Synonyms: heroin; diamorphine; acetomorphine
Molecular Formula: C21H23NO5
Molecular Weight: 369.41
Percent Composition: C 68.28%, H 6.28%, N 3.79%, O 21.66%
Literature References: Narcotic analgesic prepared from morphine and acetic anhydride: O. Hesse, Ann. 220, 203 (1883); from morphine and acetyl chloride: Small, Lutz, Chemistry of the Opium Alkaloids, Supplement No. 103, Public Health Reports, Washington (1932); K. W. Bentley, The Chemistry of the Morphine Alkaloids (Oxford, 1954). Comparison with acetylmorphine: N. B. Eddy, H. A. Howes, J. Pharmacol. Exp. Ther. 53, 430 (1935). Pharmacodynamics: J. G. Umans, C. E. Inturrisi, ibid. 218, 409 (1981). Toxicity: eidem, Eur. J. Pharmacol. 85, 317 (1982). Vapor pressure studies: A. H. Lawrence et al., Can. J. Chem. 42, 1886 (1984). Comprehensive description: D. K. Wyatt, L. T. Grady, Anal. Profiles Drug Subs. 10, 357-403 (1981).
Properties: Orthorhombic plates, tablets from ethyl acetate. mp 173°. bp12 272-274°. [a]D25 -166° (c = 1.49 in methanol). One gram dissolves in 1.5 ml chloroform, 31 ml alcohol, 100 ml ether, 1700 ml water. Slightly sol in ammonia or sodium carbonate soln, sol in alkalies, dec by boiling with water. Turns pink and emits acetic odor on prolonged exposure to air. LD50 i.v. in mice: 59 mmol/kg (Umans, Inturrisi).
Melting point: mp 173°
Boiling point: bp12 272-274°
Optical Rotation: [a]D25 -166° (c = 1.49 in methanol)
Toxicity data: LD50 i.v. in mice: 59 mmol/kg (Umans, Inturrisi)
 
Derivative Type: Hydrochloride monohydrate
Molecular Formula: C21H23NO5.HCl.H2O
Molecular Weight: 423.89
Percent Composition: C 59.50%, H 6.18%, N 3.30%, O 22.65%, Cl 8.36%
Properties: Fine crystals, mp 243-244°. [a]D24 -156° (c = 1.044). Sol in 2 parts water, 11 parts alcohol. Insol in ether.
Melting point: mp 243-244°
Optical Rotation: [a]D24 -156° (c = 1.044)
 
Derivative Type: Methyl iodide
Molecular Formula: C21H23NO5.CH3I
Molecular Weight: 511.35
Percent Composition: C 51.67%, H 5.12%, N 2.74%, O 15.64%, I 24.82%
Properties: Needles, mp 252°, [a]D15 -107° (c = 0.896).
Melting point: mp 252°
Optical Rotation: [a]D15 -107° (c = 0.896)
 
NOTE: "China White" has been used as a term for very pure Southeast Asian heroin. This term has also been erroneously used to refer to 3-methylfentanyl and a-methylfentanyl, q.v., which are potent derivs of fentanyl, q.v. See: S. Stinson, Chem. Eng. News 59, 71 (Jan. 19, 1981).
NOTE: This is a controlled substance (opium derivative): 21 CFR, 1308.11.