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CAS No 5625-37-6 , 2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonic acid

  • Name: 2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonic acid
  • Synonyms: 1,4-Piperazinediethanesulfonic acid;PIPES; 5625-37-6; Piperazine-N,N'-bis(2-ethanesulfonic acid);2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonic acid; 1,4-Piperazinebis(ethanesulfonic acid);
  • CAS Registry Number:
  • Melting Point: 300 ºC
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.505 g/cm3
  • Water Solubility: 0.1 M NaOH: 0.25 g/mL, clear, colorless
  • Safety Statements: S22;S24/25
  • Hazard Symbols: Xi
  • HS Code: 29335995
  • Flash Point: °C
  • EINECS: 227-057-6
  • Molecular Weight: 302.36832
  • InchiKey: IHPYMWDTONKSCO-UHFFFAOYSA-N
  • InChI: InChI=1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,
    15)16/h1-8H2,(H,11,12,13)(H,14,15,16)
  • Risk Statements: S22;S24/25
  • Molecular Formula: C8H18N2O6S2
  • Molecular Structure:CAS No:5625-37-6 2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonic acid

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5625-37-6 Pipes (Piperazine-N,N'-bis(2-Ethanesulfonic Acid)

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References of 2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonic acid
Title: PIPES
CAS Registry Number: 5625-37-6
CAS Name: 1,4-Piperazinediethanesulfonic acid
Synonyms: piperazine-N,N￠-bis(2-ethanesulfonic acid); 1,4-piperazinebis(ethanesulfonic acid)
Molecular Formula: C8H18N2O6S2
Molecular Weight: 302.37
Percent Composition: C 31.78%, H 6.00%, N 9.26%, O 31.75%, S 21.21%
Literature References: One of the zwitterionic N-substituted aminosulfonic acids known as "Good" buffers; active in the pH range 6-8.5. Prepn: N. Good et al., Biochemistry 5, 467 (1966). Interference with Lowry protein determn: H. M. Himmel, W. Heller, J. Clin. Chem. Clin. Biochem. 25, 909 (1987). Use as biological buffer: R. Salema, I. Brandao, J. Submicrosc. Cytol. 5, 79 (1973); S. Haviernick et al., J. Microsc. 135, 83 (1984).
 
Derivative Type: Monosodium salt
CAS Registry Number: 10010-67-0
Molecular Formula: C8H17N2NaO6S2
Molecular Weight: 324.35
Percent Composition: C 29.62%, H 5.28%, N 8.64%, Na 7.09%, O 29.60%, S 19.77%
Properties: Crystals from water and alcohol, mp >300° (dec). pKa1 ~3, pKa2 (20°): 6.82 (0.1M); 6.82 (0.2M); 6.96 (0.01M). DpKa/°C -0.0085.
Melting point: mp >300° (dec)
pKa: pKa1 ~3, pKa2 (20°): 6.82 (0.1M); 6.82 (0.2M); 6.96 (0.01M); pKa/°C -0.0085
 
Derivative Type: Disodium salt
CAS Registry Number: 76836-02-7
Synonyms: Sodium pipesate
Molecular Formula: C8H16N2Na2O6S2
Molecular Weight: 346.33
Percent Composition: C 27.74%, H 4.66%, N 8.09%, Na 13.28%, O 27.72%, S 18.52%
 
Use: Biological buffer.