Title: Dipyrone
CAS Registry Number: 5907-38-0
CAS Name: [(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1
H-pyrazol-4-yl)methylamino]methanesulfonic acid sodium salt monohydrate
Synonyms: (antipyrinylmethylamino)methanesulfonic acid sodium salt; 1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonate sodium; noraminopyrine methanesulfonate sodium; 4-methylamino-1,5-dimethyl-2-phenyl-3-pyrazolone sodium methanesulfonate; sodium methylaminoantipyrine methanesulfonate; methylmelubrin; methampyrone; metamizol; analgin; sulpyrin
Trademarks: Alginodia (Beta); Algocalmin; Bonpyrin (Takeda); Conmel (Winthrop); Divarine (Tutag); Dolazon (Graeub); D-Pron (Minnesota Pharm.); Dya-Tron (Myers-Carter); Espyre (SS Pharm.); Farmolisina (Centralvet); Feverall; Fevonil (Century); Keypyrone (Key); Metilon (Daiichi); Minalgin (Streuli); Narone (Ulmer); Nartate; Nevralgina (Climax); Nolotil (Boehringer, Ing.); Novacid; Novaldin (Winthrop); Novalgin (HMR); Novemina (Lazar); Novil; Paralgin; Pyralgin (Savage); Pyril (Maurry Biol.); Pyrilgin (Savage); Pyrojec (Maurry Biol.); Tega-Pyrone (Ortega); Unagen
Molecular Formula: C13H16N3NaO4S.H2O
Molecular Weight: 351.35
Percent Composition: C 44.44%, H 5.16%, N 11.96%, Na 6.54%, O 22.77%, S 9.13%
Literature References: Prepd by methylating the amino group of sulfamipyrine, then treating with formaldehyde sodium bisulfite soln:
DE 254711;
DE 259503;
DE 259577 (all 1911 to Hoechst).
Properties: Minute crystals from alc. Sol in water (1 g/1.5 ml), methanol. Less sol in ethanol. Practically insol in ether, acetone, benzene, chloroform. Aq solns are neutral; may acquire a yellow discoloration without apparent potency loss.
Derivative Type: Magnesium salt
CAS Registry Number: 6150-97-6
Trademarks: Magnopyrol (Abbott)
Molecular Formula: C26H32MgN6O8S2
Molecular Weight: 645.00
Percent Composition: C 48.42%, H 5.00%, Mg 3.77%, N 13.03%, O 19.84%, S 9.94%
Therap-Cat: Analgesic; antipyretic.
Therap-Cat-Vet: Analgesic; antispasmodic.
Keywords: Analgesic (Non-Narcotic); Antipyretic.
