Home > Name List By 1 > 1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-(3-methylphenoxy)propan-2-ol Germany

CAS No 59170-23-9 , 1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-(3-methylphenoxy)propan-2-ol Search by region : Germany

  • Name: 1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-(3-methylphenoxy)propan-2-ol
  • Synonyms: (+-)-bevantolol;1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-(3-methylphenoxy)propan-2-ol;Bevantololum; 1-(3,4-Dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanol; Bevantololum [INN-Latin]; Bevantolol [INN:BAN];
  • CAS Registry Number:
  • Flash Point: 267.3°C
  • Boiling Point: 518.3°C at 760 mmHg
  • Density: 1.11g/cm3
  • Refractive index: 1.55
  • Flash Point: 267.3°C
  • Molecular Weight: 345.43268
  • InchiKey: HXLAFSUPPDYFEO-UHFFFAOYSA-N
  • InChI: InChI=1S/C20H27NO4/c1-15-5-4-6-18(11-15)25-14-17(22)13-21-10-9-16-7-8-19
    (23-2)20(12-16)24-3/h4-8,11-12,17,21-22H,9-10,13-14H2,1-3H3
  • Molecular Formula: C20H27NO4
  • Molecular Structure:CAS No:59170-23-9 1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-(3-methylphenoxy)propan-2-ol

Related products

Select to

59170-23-9 Bevantolol

  • Bevantolol
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
Contact Supplier

Select to

1/1
References of 1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-(3-methylphenoxy)propan-2-ol
Title: Bevantolol
CAS Registry Number: 59170-23-9
CAS Name: 1-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-methylphenoxy)-2-propanol
Synonyms: 1-[(3,4-dimethoxyphenethyl)amino]-3-(m-tolyloxy)-2-propanol
Molecular Formula: C20H27NO4
Molecular Weight: 345.43
Percent Composition: C 69.54%, H 7.88%, N 4.05%, O 18.53%
Literature References: Cardioselective b1-adrenergic blocker. Prepn: BE 790165; A. Holmes, R. F. Meyer, US 3857891 (1973, 1974 both to Parke, Davis & Co.); M. L. Hoefle et al., J. Med. Chem. 18, 148 (1975). Pharmacology in animals: S. G. Hastings et al., Arch. Int. Pharmacodyn. Ther. 226, 81 (1977). Cardiovascular effects in animals: I. D. Dukes, E. M. Vaughan Williams, Br. J. Pharmacol. 84, 365 (1985). Cardioselectivity in asthmatic patients: C.-G. L?fdahl et al., Pharmacotherapy 4, 205 (1984). GC determn in plasma: E. J. Randinitis et al., J. Chromatogr. 308, 345 (1984). Pharmacokinetics in humans: P. Vermeij, P. van Brummelen, Eur. J. Clin. Pharmacol. 30, 375 (1986). Comparative clinical trial with hydrochlorothiazide in hypertension: C. P. Lucas et al., Clin. Ther. 8, 49 (1985). Symposium on pharmacology and clinical efficacy: Am. J. Cardiol. 58, 1E-44E (1986).
 
Derivative Type: Hydrochloride
CAS Registry Number: 42864-78-8
Manufacturers' Codes: CI-775
Trademarks: Ranestol (Parke-Davis); Sentiloc (Benzon); Vantol (Parke-Davis)
Molecular Formula: C20H27NO4.HCl
Molecular Weight: 381.89
Percent Composition: C 62.90%, H 7.39%, N 3.67%, O 16.76%, Cl 9.28%
Properties: Crystals from acetonitrile, mp 137-138°.
Melting point: mp 137-138°
 
Therap-Cat: Antianginal; antihypertensive; antiarrhythmic.
Keywords: ?Adrenergic Blocker; Antianginal; Antiarrhythmic; Antihypertensive; Aryloxypropanolamine Derivatives.