Home > Name List By 6 > 6-methoxy-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5- carboxamide China

CAS No 59338-93-1 , 6-methoxy-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5-
carboxamide Search by region : China

  • Name: 6-methoxy-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5-
    carboxamide
  • Synonyms: Alizaprida [INN-Spanish]; Plitican; Alizapridum [INN-Latin]; Alizapride [INN]; 59338-93-1; Vergentan; Liticum;6-methoxy-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5-
    carboxamide;Limican;
  • CAS Registry Number:
  • Density: 1.224 g/cm3
  • EINECS: 261-710-6
  • Molecular Weight: 315.37024
  • InchiKey: KSEYRUGYKHXGFW-UHFFFAOYSA-N
  • InChI: InChI=1S/C16H21N5O2/c1-3-6-21-7-4-5-11(21)10-17-16(22)12-8-13-14(19-20-
    18-13)9-15(12)23-2/h3,8-9,11H,1,4-7,10H2,2H3,(H,17,22)(H,18,19,20)
  • Molecular Formula: C16H21N5O2
  • Molecular Structure:CAS No:59338-93-1 6-methoxy-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5-<br />carboxamide

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References of 6-methoxy-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5-
carboxamide
Title: Alizapride
CAS Registry Number: 59338-93-1
CAS Name: 6-Methoxy-N-[[1-(2-propenyl)-2-pyrrolidinyl]methyl]-1H-benzotriazole-5-carboxamide
Synonyms: N-[(1-allyl-2-pyrrolidinyl)methyl]-6-methoxy-1H-benzotriazole-5-carboxamide
Molecular Formula: C16H21N5O2
Molecular Weight: 315.37
Percent Composition: C 60.94%, H 6.71%, N 22.21%, O 10.15%
Literature References: Prepn: BE 825605; G. Bulteau et al., US 4039672 (1975, 1977 both to Soc. d'Etudes Sci. Ind. de l'Ile-de-France). Series of articles on pharmacology and clinical studies in chemotherapy induced emesis: Sem. Hop. 58, 323-374 (1982).
Properties: Cryst from acetone, mp 139°. LD50 i.v. in mice (5 days): 92.7 mg/kg (Bulteau).
Melting point: mp 139°
Toxicity data: LD50 i.v. in mice (5 days): 92.7 mg/kg (Bulteau)
 
Derivative Type: Hydrochloride
CAS Registry Number: 59338-87-3
Trademarks: Nausilen (Baldacci); Plitican (Synthelabo); Vergentan (Synthelabo)
Molecular Formula: C16H21N5O2.HCl
Molecular Weight: 351.83
Percent Composition: C 54.62%, H 6.30%, N 19.91%, O 9.09%, Cl 10.08%
Properties: Cryst from methanol/methyl ethyl ketone, mp 206-208°.
Melting point: mp 206-208°
 
Therap-Cat: Antiemetic.
Keywords: Antiemetic.