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CAS No 60282-87-3 , Gestodene

  • Name: Gestodene
  • Synonyms: Gestodeno;Gestodene;Gestinol;13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregna-4,15-dien-20-yn-3-one;18,19-Dinorpregna-4,15-dien-20-yn-3-one,13-ethyl-17-hydroxy-, (17a)-;SHB 331;7-alpha-Ethinyl-13-ethyl-17-beta-hydroxy-4,15-gonadien-3-one ;
  • CAS Registry Number:
  • Melting Point: 190-192 ºC
  • Flash Point: 196.9 ºC
  • Boiling Point: 462.7 ºC at 760 mmHg
  • Density: 1.15 g/cm3
  • Refractive index: 1.588
  • Flash Point: 196.9 ºC
  • EINECS: 262-145-8
  • Molecular Weight: 310.43
  • InChI: InChI=1/C21H26O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,10,12-13,16-19,23H,3,5-9,11H2,1H3/t16?,17?,18?,19?,20?,21-/m0/s1
  • Molecular Formula: C21H26O2
  • Molecular Structure:CAS No:60282-87-3 Gestodene

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60282-87-3 Gestodene, 99%

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60282-87-3 GESTODENE METHYL ANALOGUE: 17ALPHA-(1-PROPYN-1-YL)-17-HYDROXY-18-METHYL-4,15-ESTRADIEN-3-ONE

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References of Gestodene
Title: Gestodene
CAS Registry Number: 60282-87-3
CAS Name: (17a)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,15-dien-20-yn-3-one
Synonyms: 17a-ethynyl-17b-hydroxy-18-methyl-4,15-estradien-3-one; 17a-ethynyl-13-ethyl-17b-hydroxy-4,15-gonadien-3-one
Manufacturers' Codes: SH B 331
Molecular Formula: C21H26O2
Molecular Weight: 310.43
Percent Composition: C 81.25%, H 8.44%, O 10.31%
Literature References: Orally active gestogen with progesterone-like profile of activity. Prepn: BE 847090; H. Hofmeister et al., US 4081537 (1977, 1978 both to Schering AG). Pharmacokinetics: B. Duesterberg et al., Contraception 24, 673 (1981); B. Duesterberg, Steroids 43, 43 (1984). Comparative study of anti-aldosterone activity: W. Losert et al., Arzneim.-Forsch. 35, 459 (1985). Clinical trial as oral contraceptive: G. Hoppe, Adv. Contracept. 3, 159 (1987).
Properties: Crystals from acetone-hexane, mp 197.9°.
Melting point: mp 197.9°
 
Derivative Type: Mixture with ethinyl estradiol
CAS Registry Number: 109852-02-0
Trademarks: Femodene (Schering AG); Femovan (Schering AG); Ginoden (Schering AG); Gynera (Schering AG); Harmonet (Wyeth); Meliane (Schering AG); Milvane (Schering AG); Minulet (Wyeth); Phaeva (Schering AG); Tri-Minulet (Wyeth)
 
Therap-Cat: Progestogen. In combination with estrogen as oral contraceptive.
Keywords: Contraceptive (Oral); Progestogen.