Home > Name List By other > (2-bromophenyl)methyl-ethyl-dimethylazanium

CAS No 61-75-6 , (2-bromophenyl)methyl-ethyl-dimethylazanium

  • Name: (2-bromophenyl)methyl-ethyl-dimethylazanium
  • Synonyms: Bretylium tosilate; Bretylium p-toluenesulfonate; Darenthin; Bretylan;4-methylbenzenesulfonate;(2-bromophenyl)methyl-ethyl-dimethylazanium;Bretylol; 61-75-6; Ornid; Bretylate;
  • CAS Registry Number:
  • Safety Statements: A poison by ingestion, intraperitoneal, subcutaneous, intravenous, and intramuscular routes. An anti-adrenergic agent and antiarrhythmic cardiac depressant. When heated to decomposition it emits very toxic fumes of SOx, NH3, NOx, and Br−. See also SULFONATES.
  • EINECS: 200-516-8
  • Molecular Weight: 414.35706
  • InchiKey: KVWNWTZZBKCOPM-UHFFFAOYSA-M
  • InChI: InChI=1S/C11H17BrN.C7H8O3S/c1-4-13(2,
    3)9-10-7-5-6-8-11(10)12;1-6-2-4-7(5-3-6)11(8,9)10/h5-8H,4,9H2,
    1-3H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
  • Molecular Formula: C18H24BrNO3S
  • Molecular Structure:CAS No:61-75-6 (2-bromophenyl)methyl-ethyl-dimethylazanium
Search by region :

Select to

61-75-6 BRETYLIUM TOSYLATE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
Contact Supplier

61-75-6 Bretylium Tosylate

  • Bretylium Tosylate
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
Contact Supplier

61-75-6 Bretylium Tosylate

Contact Supplier

61-75-6 Bretylium Tosilate

Contact Supplier

61-75-6 Bretylium Tosylate

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
  • Tel: +86-(21)-58116473
  • Fax: +86-(21)-61094103
  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
Contact Supplier

61-75-6 Bretylium tosilate

  • China shanghai sphchem co.,ltd [Manufacturers]
  • Tel: +86-21-56491756 13512199871
  • Fax: 0
  • Address: NO.133, Wuye, Yangxin Road ,Shanghai China shanghai,shanghai ChinaChina
Contact Supplier

61-75-6 Bretylium Tosylate

  • China Haihang Industry Co., Ltd. []
  • Tel: +86-(531)-88032799
  • Fax: +86-(531)-85821093
  • Address: 2/F, East Tower, Bldg 12, No. 2 Qilihe Road, Jinan 250100, ,China
Contact Supplier

61-75-6 Bretylium Tosylate

  • Germany Fox Chemicals GmbH [Manufacturer]
  • Tel: +49.7240.927151/ +49.160.95781845 (Mobile)
  • Fax: +49.7240.927150
  • Address: Fox Chemicals GmbH
    Bockstalstr.10 A
    D-76327 Pfinztal-Germany ,Germany
Contact Supplier

61-75-6 Bretylium tosilate

  • China Maple Chemical Co.,ltd. [Manufacturer]
  • Tel: 86-574- 87512300
  • Fax: 86-574-82095182
  • Address: No.347,Sanbei Road,Sanbei Town,Cixi ,Zhejiang,China Ningbo,ZhejiangChina
Contact Supplier

61-75-6 Bretylium Tosylate

  • India Manus Aktteva []
  • Tel: +91-(79)-65123395
  • Fax: +91-(79)-26463395
  • Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006, ,India
Contact Supplier

Select to

References of (2-bromophenyl)methyl-ethyl-dimethylazanium
Title: Bretylium Tosylate
CAS Registry Number: 61-75-6
CAS Name: 2-Bromo-N-ethyl-N,N-dimethylbenzenemethanaminium salt with 4-methylbenzenesulfonic acid (1:1)
Synonyms: (o-bromobenzyl)ethyldimethylammonium p-toluenesulfonate; N-ethyl-N-o-bromobenzyl-N,N-dimethylammonium tosylate
Trademarks: Bretylate (GSK); Bretylol (GSK)
Molecular Formula: C18H24BrNO3S
Molecular Weight: 414.36
Percent Composition: C 52.18%, H 5.84%, Br 19.28%, N 3.38%, O 11.58%, S 7.74%
Literature References: Prepn: Copp, Stephenson, US 3038004 (1962 to Burroughs Wellcome). Metabolism: R. Kuntzman et al., Clin. Pharmacol. Ther. 11, 829 (1970). Toxicity study: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971). Review of pharmacology: R. H. Heissenbuttel, J. T. Bigger, Ann. Intern. Med. 91, 229-238 (1979); R. J. Lee et al., in Pharmacological and Biochemical Properties of Drug Substances vol. 2, M. E. Goldberg, Ed. (Am. Pharm. Assoc., Washington, DC, 1979) pp 148-164. Comprehensive description: J. E. Carter et al., Anal. Profiles Drug Subs. 9, 71-86 (1980).
Properties: Crystalline powder, mp 97-99°. Extremely bitter taste. uv max: 278, 271, 264 nm. Freely sol in water, methanol, ethanol. Practically insol in ether, ethyl acetate, hexane. LD50 in mice (mg/kg): 400 orally; 250 i.m. (Goldenthal).
Melting point: mp 97-99°
Absorption maximum: uv max: 278, 271, 264 nm
Toxicity data: LD50 in mice (mg/kg): 400 orally; 250 i.m. (Goldenthal)
Therap-Cat: Antiadrenergic; antiarrhythmic (class III).
Keywords: Antiarrhythmic.