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CAS No 61-90-5 , (2S)-2-amino-4-methylpentanoic acid

  • Name: (2S)-2-amino-4-methylpentanoic acid
  • Synonyms: L-leucine; (S)-Leucine; (S)-2-Amino-4-methylpentanoic acid; Leucinum; 61-90-5; leucine; (S)-2-Amino-4-methylvaleric acid; L-alpha-Aminoisocaproic acid;(2S)-2-amino-4-methylpentanoic acid;
  • CAS Registry Number:
  • Melting Point: 286-288 ºC
  • Density: 1,293 g/cm3
  • Alpha: 15.4 º (C=4, 6N HCL)
  • Water Solubility: 22.4 G/L (20 C)
  • Safety Statements: 24/25
  • EINECS: 200-522-0
  • Molecular Weight: 131.17292
  • InchiKey: ROHFNLRQFUQHCH-YFKPBYRVSA-N
  • InChI: InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
  • Risk Statements: S24/25
  • Molecular Formula: C6H13NO2
  • Molecular Structure:CAS No:61-90-5 (2S)-2-amino-4-methylpentanoic acid
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61-90-5 L-Leucine

  • United States Promy International Group [Importer/Exporter]
  • Tel: +1-(888)-918-3888, 510-758-1388
  • Fax: +1-(510)-758-9388
  • Address: 130 Travalini Court, El Sobrante, California 94803, Sobrante,SobranteUnited States
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61-90-5 L-Leucine

  • China Siwei Development Group Ltd [Manufacturer, Distributor/Wholesaler]
  • Tel: 86-571-57109529
  • Fax: 86-571-57109690
  • Address: Room 34-1 Xiaoshan Hangzhou China null,ZhejiangChina
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61-90-5 L-Leucine

  • China Glorient (Xiamen) Impex Co., Ltd. [Manufacturers]
  • Tel: +86-(592)-559-7140
  • Fax: +86-(592)-559-7141
  • Address: Room B213, Xinxin Jingdi Plaza, No.396 Jia He Road, Xiamen 361009, Xiamen,fujianChina
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61-90-5 L-LEUCINE

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
  • Fax: +86-571-81956190
  • Address: 425 MOGAN HILL ROAD ,
    HANGZHOU, 310011 CHINA null,nullChina
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61-90-5 L-LEUCINE

  • China Shanghai Trustin Chemical Co., Ltd (STCC) [Manufacturer]
  • Tel: +86-21-50903441
  • Fax: +86-21-50904419
  • Address: Trusitin Chemical
    Add.: 14D, 1361 Dongfang Rd.,
    Pudong New Area, Shanghai 200127
    Tel: +86-21-50903441 / 50904436 / 58736479
    Fax: +86-21-50904419
    E-mail: sales@etrustin.com manager@etrustin.com null,nullChina
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61-90-5 L-LEUCINE

  • China Song's PharmChem Inc. [Manufacturer]
  • Tel: +86 21 66125360
  • Fax: +86 21 66125362
  • Address: Song's PharmChem Inc.
    Shanghai, China 200442 null,nullChina
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61-90-5 L-Leucine

  • China Hangzhou Think Chemical Co. Ltd [Manufacturers]
  • Tel: 86-571-81956191/81956084/89986307/81956192
  • Fax: 86-571-81956190
  • Address: ROOM 719 BUILDING D MEIDU PLAZA 789 MOGANSHAN ROAD HANGZHOU 310011 CHINA null,zhejiangChina
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61-90-5 L-Leucine

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61-90-5 L-Leucine

  • China Xinshiji Pharmaceutical Co., Ltd. [Manufacturers]
  • Tel: +86-591-88011158
  • Fax: +86-591-88045215
  • Address: Unit F, 24/F, World Trade Plaza, No.71, Wusi Road, Fuzhou 350001, China Fuzhou,FujianChina
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61-90-5 L-Leucine

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References of (2S)-2-amino-4-methylpentanoic acid
Title: Leucine
CAS Registry Number: 61-90-5
CAS Name: L-Leucine
Synonyms: Leu; L; 2-amino-4-methylvaleric acid; a-aminoisocaproic acid; (S)-2-amino-4-methylpentanoic acid
Molecular Formula: C6H13NO2
Molecular Weight: 131.17
Percent Composition: C 54.94%, H 9.99%, N 10.68%, O 24.39%
Literature References: An essential amino acid for human development. Discovery of leucine is attributed to Proust in 1819 who reported its separation from fermented milk curds. Early chemistry and biochemistry: Amino Acids and Proteins, D. M. Greenberg, Ed. (Charles C. Thomas, Springfield, IL, 1951) 950 pp., passim; J. P. Greenstein, M. Winitz, Chemistry of the Amino Acids vols 1-3 (John Wiley and Sons, Inc., New York, 1961) pp. 2075-2096, passim. Chromatographic determn of specific activity in biological fluids: E. P. Donahue et al., J. Chromatogr. 571, 29 (1991); separation of isotopes: P. Q. Baumann et al., ibid. 573, 11 (1992). Metabolism in humans: K. J. Motil et al., Metabolism 30, 783 (1981); in children receiving parenteral nutrition: O. Goulet et al., Am. J. Physiol. 265, E540 (1993). Kinetics modelling in humans: C. Cobelli et al., ibid. 261, E539 (1991).
Properties: White glistening hexagonal plates from aq alc. d18 1.293. Sublimes at 145-148°. Dec 293-295° (rapid heating, sealed tube). [M]D +21.0° (5N HCl); [M]D +29.5° (glacial acetic acid). [a]D25 -10.8° (c = 2.2); [a]D26 +15.1° in 6N HCl (38 mols HCl per mol leucine); [a]D20 +7.6° in 3N NaOH (30 mols NaOH per mol leucine). Rf value 0.79. Soly in water (g/l): 22.7 (0°); 24.26 (25°); 28.87 (50°); 38.23 (75°); 56.38 (100°); in 99% alcohol: 0.72; in acetic acid: 10.9. Insol in ether.
Optical Rotation: [a]D25 -10.8° (c = 2.2); [a]D26 +15.1° in 6N HCl (38 mols HCl per mol leucine); [a]D20 +7.6° in 3N NaOH (30 mols NaOH per mol leucine)
Density: d18 1.293
 
Derivative Type: DL-Form
Properties: Leaflets fom water. Sweet taste. Dec 332° (also reported as 290°). Sublimes. pK1 2.36; pK2 9.60. Soly in water (g/l): 7.97 (0°); 9.91 (25°); 14.06 (50°); 22.76 (75°); 42.06 (100°); in 90% alcohol: 1.3. Insol in ether.
pKa: pK1 2.36; pK2 9.60
 
Derivative Type: Hydrochloride
Molecular Formula: C6H13NO2.HCl
Molecular Weight: 167.63
Percent Composition: C 42.99%, H 8.42%, N 8.36%, O 19.09%, Cl 21.15%
Properties: Crystals. Freely sol in water.
 
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