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CAS No 61337-67-5 , Mirtazapine

  • Name: Mirtazapine
  • Synonyms: Rexer; Remergon;Remeron; Zispin; Promyrtil; Mepirzepine; Remergil; Norset; Remeron SolTab;Mirtazapine;
  • CAS Registry Number:
  • Flash Point: 215.3 ºC
  • Boiling Point: 432.4 ºC at 760 mmHg
  • Density: 1.22 g/cm3
  • Water Solubility: DMSO: 8 mg/mL, soluble
  • Safety Statements: Human systemic effects. When heated to decomposition it emits toxic vapors of NOx.
  • Flash Point: 215.3 ºC
  • EINECS: 288-060-6
  • Molecular Weight: 265.35286
  • InchiKey: RONZAEMNMFQXRA-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-
    18-17(14)20/h2-8,16H,9-12H2,1H3
  • Risk Statements: S22;S24/25
  • Molecular Formula: C17H19N3
  • Molecular Structure:CAS No:61337-67-5 Mirtazapine

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References of Mirtazapine
Title: Mirtazapine
CAS Registry Number: 61337-67-5
CAS Name: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
Synonyms: 2-methyl-1,2,3,4,10,14b-hexahydrobenzo[c]pyrazino[1,2-a]pyrido[3,2-f]azepine; 6-azamianserin; mepirzepine
Manufacturers' Codes: Org-3770
Trademarks: Remeron (Organon); Zispin (Organon)
Molecular Formula: C17H19N3
Molecular Weight: 265.35
Percent Composition: C 76.95%, H 7.22%, N 15.84%
Literature References: a2-Adrenergic blocker; analog of mianserin, q.v. Prepn: W. J. Van der Burg, DE 2614406; idem, US 4062848 (1976, 1977 both to AKZO). GC determn in plasma: J. E. Paanakker, H. J. M. Van Hal, J. Chromatogr. 417, 203 (1987). Pharmacology and mechanism of action study: T. De Boer et al., Neuropharmacology 27, 399 (1988). Clinical comparison with amitriptyline, q.v.: W. T. Smith et al., Psychopharmacol. Bull. 26, 191 (1990). Review of clinical experience in mood and anxiety disorders: M. J. Ostacher et al., Expert Rev. Neurotherapeut. 3, 425-433 (2003); and of clinical pharmacokinetics, safety and efficacy: A. Szegedi, N. Schwertfeger, Expert Opin. Pharmacother. 6, 631-641 (2005).
Properties: White crystals from petr ether, mp 114-116°. Sol in methanol and chloroform.
Melting point: mp 114-116°
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Tetracyclics.