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CAS No 61825-94-3 , Oxaliplatin

  • Name: Oxaliplatin
  • Synonyms: Oxaliplatin;trans-L-Diaminocyclohexane oxalatoplatinum;
  • CAS Registry Number:
  • Transport: 2811
  • Water Solubility: Soluble
  • Safety Statements: R36/37/38;R40;R42/43
  • Hazard Symbols: Xn: Harmful;
  • Molecular Weight: 395.27
  • InChI: InChI=1S/C6H14N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-6H,1-4,7-8H2;(H,3,4)(H,5,6);/q;;+2/p-2
  • Risk Statements: S26;S36
  • Molecular Formula: C8H12N2O4Pt
  • Molecular Structure:CAS No:61825-94-3 Oxaliplatin

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References of Oxaliplatin
Title: Oxaliplatin
CAS Registry Number: 61825-94-3
CAS Name: (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN￠][ethanedioato(2-)-kO1,kO2]platinum
Synonyms: [(1R,2R)-1,2-cyclohexanediamine-N,N￠][oxalato (2-)-O,O￠]platinum; oxalato (1R,2R-cyclohexanediamine)platinum(II); Pt(oxalato)(trans-l-dach); oxalato (trans-l-1,2-diaminocyclohexane)platinum (II); oxalatoplatin; oxalatoplatinum; l-OHP
Manufacturers' Codes: RP-54780; NSC-266046
Trademarks: Eloxatin (Sanofi-Aventis); Elplat (Debiopharm)
Molecular Formula: C8H14N2O4Pt
Molecular Weight: 397.29
Percent Composition: C 24.19%, H 3.55%, N 7.05%, O 16.11%, Pt 49.10%
Literature References: Third generation platinum complex. Prepn and antitumor activity: Y. Kidani et al., J. Med. Chem. 21, 1315 (1978); Y. Kidani et al., Gann 71, 637 (1980). Crystal structure: M. A. Bruck et al., Inorg. Chim. Acta 92, 279 (1984). FAB and LAMMA MS analysis: J. Claereboudt et al., J. Pharm. Biomed. Anal. 7, 1599 (1989). Pharmacokinetics: R. Kizu et al., Cancer Chemother. Pharmacol. 31, 475 (1993). Clinical evaluation in colorectal cancer: F. Levi et al., Eur. J. Cancer 29A, 1280 (1993). Brief review of antitumor and clinical activity: G. Mathé et al., Biomed. Pharmacother. 43, 237-250 (1989). Review of clinical experience in combination therapy for colorectal cancer: D. Simpson et al., Drugs 63, 2127-2156 (2003).
Properties: Colorless, thin triangular plates with truncated vertices. Sol in water 7.9 mg/ml.
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Platinum Complexes.