Home > Name List By other > (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine

CAS No 61869-08-7 , (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine

  • Name: (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine
  • Synonyms: Frosinor;Paxil; Paroxetina [INN-Spanish]; Aropax;(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine; Paroxetinum [INN-Latin]; Pexeva; Paroxetinum; Paxil CR; Seroxat;
  • CAS Registry Number:
  • Transport: 3249
  • Density: 1.213 g/cm3
  • Refractive index: 1.561
  • Water Solubility: SOLVENT
  • Hazard Symbols: UN NO.
  • Molecular Weight: 329.365403
  • InchiKey: AHOUBRCZNHFOSL-YOEHRIQHSA-N
  • InChI: InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-
    6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1
  • Molecular Formula: C19H20FNO3
  • Molecular Structure:CAS No:61869-08-7 (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine

Related products

Search by region :

Select to

61869-08-7 Paroxetine

  • China Taizhou Overseas Int'l Ltd. [Importer/Exporter]
  • Tel: +86-576-8881 2802
  • Fax: 86-576-88811658
  • Address: 126-8 QINGNIAN ROAD JIAOJIANG TAIZHOU ZHEJIANG CHINA Taizhou,ZhejiangChina
Contact Supplier

61869-08-7 paroxetine

Contact Supplier

61869-08-7 paroxetine

  • China TPNChina [Importer/Exporter]
  • Tel: +86-21-38726808
  • Fax: +86-21-38726806
  • Address: No.2577,Dongfang Road,Weifang,China Shanghai,ShanghaiChina
Contact Supplier

61869-08-7 Paroxetine HCl

  • Paroxetine HCl, 99.0%min
  • China Lemman Laboratories International Co., Ltd. [Importer/Exporter]
  • Tel: +86-(571)-8697-7060
  • Fax: +86-(571)-8697-6607
  • Address: Room 223, Tianhu Blng, No.79 Jiaogong Road, Hangzhou, Zhejiang, hangzhou,zhejaingChina
Contact Supplier

61869-08-7 paroxetine

  • China everchem shanghai office [Manufacturers]
  • Tel: +86-21-61043575
  • Fax: +86-21-61043577
  • Address: room1602 No.1518 minsheng Road pudong shanghai shanghai,shanghaiChina
Contact Supplier

61869-08-7 PAROXETINE

  • China Shanghai Everchem Co.,Ltd. [Manufacturer]
  • Tel: +86-21-5192-3949
  • Fax: +86-21-5192-3940
  • Address: No.277 Zheqiao Road,
    Shanghai 201206 China null,nullChina
Contact Supplier

61869-08-7 PAROXETINE

  • China NINGBO PANGS CHEM INT'L CO.,LTD [Manufacturer]
  • Tel: +86-574-27666821
  • Fax: +86-574-27668686 / 27668810
  • Address: FLOOR 21,BUILDING 11,
    XINTIANDI,NO.689,
    SHIJIROAD,
    NINGBO,CHINA 315040 null,nullChina
Contact Supplier

61869-08-7 Paroxetine HCl

  • China SNC International Co., Ltd. [Distributor/Wholesaler]
  • Tel: +86-(22)-2822-1962
  • Fax: +86-(22)-2822-1960
  • Address: Room No. 711, Minmetals Building, No. 47, Xiangjiang Road, Hexi District, Tianjin 300210, null,TianjinChina
Contact Supplier

61869-08-7 Paroxetine HCl

  • China Advan Pharmachem Co., Ltd. [Manufacturers]
  • Tel: +86-(21)-6875-3906, 5058-1635
  • Fax: +86-(21)-5831-8593
  • Address: Room 1418 YuAn Mansion, No.738 Dongfang Road, Pu Dong, Shanghai, shanghai,shanghaiChina
Contact Supplier

61869-08-7 paroxetine

  • Canada Molcan Corporation [Importer/Exporter]
  • Tel: 905-731-5537, 905-731-6592, 1-888-237-7579
  • Fax: +416-267-9144
  • Address: 70 East Beaver Creek Road #39 Richmond Hill, Toronto, Ontario, Canada L4B 3B2 Toronto,OntarioCanada
Contact Supplier

Select to

6/9
Previous 1 2 3 4 5 6 7 8 9 Next
References of (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine
Title: Paroxetine
CAS Registry Number: 61869-08-7
CAS Name: (3S-trans)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine
Synonyms: (-)-trans-4-(p-fluorophenyl)-3-[[3,4-(methylenedioxy)phenoxy]methyl]piperidine
Manufacturers' Codes: FG-7051; BRL-29060
Molecular Formula: C19H20FNO3
Molecular Weight: 329.37
Percent Composition: C 69.28%, H 6.12%, F 5.77%, N 4.25%, O 14.57%
Literature References: Selective serotonin (5-HT) reuptake inhibitor (SSRI). Prepn: J. A. Christensen, R. F. Squires, DE 2404113; eidem, US 3912743; US 4007196 (1974, 1975, 1977 all to Ferrosan); of crystalline hydrochloride hemihydrate: R. D. B. Barnes et al., EP 223403; US 4721723 (1987, 1988 both to Beecham). Characterization of serotonin inhibition: J. Buus Lassen, Eur. J. Pharmacol. 47, 351 (1978). Binding to serotonin transporter complex: E. Habert et al., ibid. 118, 107 (1985). Clinical pharmacokinetics: J. Lund et al., Acta Pharmacol. Toxicol. 51, 351 (1982). HPLC determn in plasma: M. A. Brett et al., J. Chromatogr. 419, 438 (1987). Clinical trial in obsessive-compulsive disorder: J. Zohar et al., Br. J. Psychiatry 169, 468 (1996); in social phobia: M. B. Stein et al., J. Am. Med. Assoc. 280, 708 (1998). Review of pharmacology and clinical use in depression: K. L. Dechant, S. P. Clissold, Drugs 41, 225-253 (1991); of clinical experience: D. Dunner, R. Kumar, Pharmacopsychiatry 31, 89-101 (1998); of use in generalized social anxiety disorder: M. Van Ameringen et al., Expert Opin. Pharmacother. 6, 819-830 (2005).
 
Derivative Type: Hydrochloride hemihydrate
CAS Registry Number: 110429-35-1; 78246-49-8 (hydrochloride)
Trademarks: Aropax (GSK); Deroxat (GSK); Paxil (GSK); Seroxat (GSK)
Molecular Formula: C19H20FNO3.HCl.?H2O
Molecular Weight: 374.83
Percent Composition: C 60.88%, H 5.92%, F 5.07%, N 3.74%, O 14.94%, Cl 9.46%
Properties: Crystals, mp 129-131°. Soly in water: 5.4 mg/ml.
Melting point: mp 129-131°
 
Derivative Type: Maleate
CAS Registry Number: 64006-44-6
Properties: Crystals from ethanol-ether, mp 136-138°. [a]D -87° (c = 5 in ethanol). LD50 in mice (mg/kg): 845 s.c.; 500 orally (Christensen, Squires, 1977).
Melting point: mp 136-138°
Optical Rotation: [a]D -87° (c = 5 in ethanol)
Toxicity data: LD50 in mice (mg/kg): 845 s.c.; 500 orally (Christensen, Squires, 1977)
 
Therap-Cat: Antidepressant; antiobsessional.
Keywords: Antidepressant; Bicyclics; Serotonin Uptake Inhibitor; Antiobsessional.