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CAS No 62613-82-5 , 2-(4-hydroxy-2-oxopyrrolidin-1-yl)acetamide

  • Name: 2-(4-hydroxy-2-oxopyrrolidin-1-yl)acetamide
  • Synonyms: Hydroxypiracetam; ISF 2522;2-(4-hydroxy-2-oxopyrrolidin-1-yl)acetamide; (+-)-Oxiracetam; Neuractiv; Neuromet; 4-Hydroxypiracetam; 62613-82-5; 4-Hydroxy-2-oxopyrrolidine-N-acetamide;
  • CAS Registry Number:
  • Density: 1.416
  • Safety Statements: 26-36
  • Hazard Symbols: Xi: Irritant;
  • Molecular Weight: 158.1552
  • InchiKey: IHLAQQPQKRMGSS-UHFFFAOYSA-N
  • InChI: InChI=1S/C6H10N2O3/c7-5(10)3-8-2-4(9)1-6(8)11/h4,9H,1-3H2,(H2,7,10)
  • Risk Statements: 36/38
  • Molecular Formula: C6H10N2O3
  • Molecular Structure:CAS No:62613-82-5 2-(4-hydroxy-2-oxopyrrolidin-1-yl)acetamide

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62613-82-5; 88929-35-5 Oxiracetam

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References of 2-(4-hydroxy-2-oxopyrrolidin-1-yl)acetamide
Title: Oxiracetam
CAS Registry Number: 62613-82-5
CAS Name: 4-Hydroxy-2-oxo-1-pyrrolidineacetamide
Synonyms: 2-(4-hydroxypyrrolidin-2-on-1-yl)acetamide; hydroxypiracetam
Manufacturers' Codes: CT-848; ISF-2522
Trademarks: Neuractiv (Novartis); Neuromet (SKB)
Molecular Formula: C6H10N2O3
Molecular Weight: 158.16
Percent Composition: C 45.56%, H 6.37%, N 17.71%, O 30.35%
Literature References: Analog of piracetam, q.v., with psychostimulant activity. Prepn: G. Pifferi, M. Pinza, DE 2635853; eidem, US 4118396 (1977, 1978 both to I.S.F.); eidem, Farmaco Ed. Sci. 32, 602 (1977). Effect on learning and memory in animals and prepn of enantiomers: S. Banfi et al., ibid. 39, 16 (1984). Effect in animals with cerebral impairment: S. Banfi et al., Pharmacol. Res. Commun. 16, 67 (1984). Pharmacokinetics in humans: E. Perucca et al., Eur. J. Drug Metab. Pharmacokinet. 9, 267 (1984). Clinical evaluation in organic brain syndrome: B. Saletu et al., Neuropsychobiology 13, 44 (1985).
Properties: White, microcrystalline powder from methanol, mp 165-168°.
Melting point: mp 165-168°
 
Derivative Type: (R)-Form
Properties: Crystals from acetone + water, mp 135-136°. [a]D +36.2° (c = 1.00 in water).
Melting point: mp 135-136°
Optical Rotation: [a]D +36.2° (c = 1.00 in water)
 
Derivative Type: (S)-Form
Properties: Crystals from acetone + water, mp 135-136°. [a]D -36.0° (c = 1.00 in water).
Melting point: mp 135-136°
Optical Rotation: [a]D -36.0° (c = 1.00 in water)
 
Therap-Cat: Nootropic.
Keywords: Nootropic.