Home > Name List By other > [1-(tert-butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]propan-2-yl] benzoate Germany

CAS No 62658-63-3 , [1-(tert-butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]propan-2-yl]
benzoate Search by region : Germany

  • Name: [1-(tert-butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]propan-2-yl]
    benzoate
  • Synonyms: Bopindolol (INN); Bopindolol [INN]; (+-)-Bopindolol; Wandonorm; NCGC00163155-01; Bopindololum [INN-Latin]; 62658-63-3;Sandonorm;[1-(tert-butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]propan-2-yl]
    benzoate;
  • CAS Registry Number:
  • Density: 1.143 g/cm3
  • Refractive index: 1.592
  • Molecular Weight: 380.48002
  • InchiKey: UUOJIACWOAYWEZ-UHFFFAOYSA-N
  • InChI: InChI=1S/C23H28N2O3/c1-16-13-19-20(25-16)11-8-12-21(19)27-15-18(14-24-23
    (2,3)4)28-22(26)17-9-6-5-7-10-17/h5-13,18,24-25H,14-15H2,1-4H3
  • Molecular Formula: C23H28N2O3
  • Molecular Structure:CAS No:62658-63-3 [1-(tert-butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]propan-2-yl]<br />benzoate

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62658-63-3 Bopindolol

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References of [1-(tert-butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]propan-2-yl]
benzoate
Title: Bopindolol
CAS Registry Number: 62658-63-3
CAS Name: 1-[(1,1-Dimethylethyl)amino]-3-[(2-methyl-1H-indol-4-yl)oxy]-2-propanol benzoate ester
Synonyms: (±)-1-(tert-butylamino)-3-[(2-methylindol-4-yl)oxy]-2-propanol benzoate (ester)
Molecular Formula: C23H28N2O3
Molecular Weight: 380.48
Percent Composition: C 72.60%, H 7.42%, N 7.36%, O 12.62%
Literature References: Nonselective b-adrenergic blocker. Prepn: F. Troxler, F. Seemann, DE 2635209; eidem, US 4340541 (1977, 1982 both to Sandoz). Clinical pharmacology: P. van Brummelen et al., Eur. J. Clin. Pharmacol. 22, 491 (1982). HPLC determn in plasma: C. J. Oddie et al., J. Chromatogr. 273, 469 (1983). Effect on plasma lipid fractions: P. van Brummelen et al., Br. J. Clin. Pharmacol. 17, 86 (1984). Pharmacokinetics: R. Platzer et al., Clin. Pharmacol. Ther. 36, 5 (1984). Clinical trials in hypertension: U. L. Hulthen et al., J. Cardiovasc. Pharmacol. 5, 426 (1983); W. J. Schiess et al., Eur. J. Clin. Pharmacol. 27, 529 (1984).
Properties: Sol in ether, methylene chloride. LD50 i.v. in mice: 17 mg/kg (Troxler, Seemann, 1977).
Toxicity data: LD50 i.v. in mice: 17 mg/kg (Troxler, Seemann, 1977)
 
Derivative Type: Maleate
CAS Registry Number: 62658-64-4
Trademarks: Sandonorm (Novartis)
Molecular Formula: C23H28N2O3.C4H4O4
Molecular Weight: 496.55
Percent Composition: C 65.31%, H 6.50%, N 5.64%, O 22.55%
 
Derivative Type: Malonate
CAS Registry Number: 82857-38-3
Manufacturers' Codes: LT-31-200
Trademarks: Wandonorm (Novartis)
Molecular Formula: C23H28N2O3.C3H4O4
Molecular Weight: 484.54
Percent Composition: C 64.45%, H 6.66%, N 5.78%, O 23.11%
 
Therap-Cat: Antihypertensive.
Keywords: ?Adrenergic Blocker; Antihypertensive; Aryloxypropanolamine Derivatives.