Home > Name List By 1 > 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2- ol Germany

CAS No 63659-18-7 , 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-
ol Search by region : Germany

  • Name: 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-
    ol
  • Synonyms: CHEBI:3082; Kerlone; Betazolol;Betoptic;1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-
    ol; Betaxololum; Betaxolol HCL; 63659-18-7; Betaxololum [INN-Latin];
  • CAS Registry Number:
  • Density: 1.067 g/cm3
  • Molecular Weight: 307.42776
  • InchiKey: NWIUTZDMDHAVTP-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H29NO3/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-
    12-16-3-4-16/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3
  • Molecular Formula: C18H29NO3
  • Molecular Structure:CAS No:63659-18-7 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-<br />ol

Related products

Select to

63659-18-7 BETAXOLOL

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
Contact Supplier

Select to

1/1
References of 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-
ol
Title: Betaxolol
CAS Registry Number: 63659-18-7
CAS Name: 1-[4-[2-(Cyclopropylmethoxy)ethyl]-phenoxy]-3-[(1-methylethyl)amino]-2-propanol
Synonyms: (±)-1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol
Molecular Formula: C18H29NO3
Molecular Weight: 307.43
Percent Composition: C 70.32%, H 9.51%, N 4.56%, O 15.61%
Literature References: Cardioselective b1-adrenergic blocker. Prepn: P. M. J. Manoury et al., DE 2649605; eidem, US 4252984 (1977, 1981 both to Synthelabo). Blood concn and pharmacodynamic effects: S. J. Warrington et al., Br. J. Clin. Pharmacol. 10, 449 (1980). Pharmacokinetics: G. Bianchetti et al., Arzneim.-Forsch. 30, 1912 (1980). Cardiovascular effects in normal volunteers: P. J. Cadigan et al., Br. J. Clin. Pharmacol. 9, 569 (1980). Efficacy and pharmacokinetics: K. Balnave et al., ibid. 11, 171 (1981). Use in treatment of glaucoma: A. R. Berrospi, H. M. Leibowitz, Arch. Ophthalmol. 100, 943 (1982). Antihypertensive effect: M. Pathe et al., Therapie 37, 75 (1982). Book: Betaxolol and Other b1-Adrenoceptor Antagonists, P. L. Morselli et al., Eds. (Raven Press, New York, 1983) 385 pp.
Properties: Crystals from petr ether, mp 70-72°.
Melting point: mp 70-72°
 
Derivative Type: Hydrochloride
CAS Registry Number: 63659-19-8
Manufacturers' Codes: SLD-212; SL-75.212
Trademarks: Betoptic (Alcon); Betoptima (Alcon); Kerlone (Synthelabo)
Molecular Formula: C18H29NO3.HCl
Molecular Weight: 343.89
Percent Composition: C 62.87%, H 8.79%, N 4.07%, O 13.96%, Cl 10.31%
Properties: Crystals from acetone, mp 116°. LD50 in mice (mg/kg): 944 orally; 37 i.v. (Manoury).
Melting point: mp 116°
Toxicity data: LD50 in mice (mg/kg): 944 orally; 37 i.v. (Manoury)
 
Therap-Cat: Antihypertensive; antiglaucoma.
Keywords: ?Adrenergic Blocker; Antiglaucoma; Antihypertensive; Aryloxypropanolamine Derivatives.