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CAS No 64228-81-5 , benzenesulfonate

  • Name: benzenesulfonate
  • Synonyms: Besilate d'atracurium; Besilato de atracurio; 64228-81-5; Tracrium; Atracurium besilate;5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,
    7-dimethoxy-2-methyl-3,
    4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl
    3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,
    4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate;Atracurium besylate; Atracurii besilas; BW-33A;benzenesulfonate;
  • CAS Registry Number:
  • Water Solubility: H2O: ~27 mg/mL
  • EINECS: 264-743-4
  • Molecular Weight: 1243.47918
  • InchiKey: XXZSQOVSEBAPGS-UHFFFAOYSA-L
  • InChI: InChI=1S/C53H72N2O12.2C6H6O3S/c1-54(22-18-38-32-48(62-7)50(64-9)34-40
    (38)42(54)28-36-14-16-44(58-3)46(30-36)60-5)24-20-52(56)66-26-12-11-13-
    27-67-53(57)21-25-55(2)23-19-39-33-49(63-8)51(65-10)35-41(39)43(55)29-
    37-15-17-45(59-4)47(31-37)61-6;2*7-10(8,9)6-4-2-1-3-5-6/h14-17,30-35,
    42-43H,11-13,18-29H2,1-10H3;2*1-5H,(H,7,8,9)/q+2;;/p-2
  • Molecular Formula: C65H82N2O18S2
  • Molecular Structure:CAS No:64228-81-5 benzenesulfonate

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64228-81-5 ATRACURIUM BESYLATE

  • United States Carbomer, Inc. [Manufacturer]
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64228-81-5 Atracurium Besylate

  • United States Tecoland Corporation null
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  • Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428, null,nullUnited States
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64228-81-5 Atracurium Besylate

  • China Shanghai Richem International Co., Ltd. null
  • Tel: +86-(21)-31263688
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  • Address: Room 603, Golden Eagle Mansion A, No.1518 Minsheng Road, Pudong, Shanghai 200135, shanghai,shanghaiChina
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64228-81-5 Atracurium besylate

  • Atracurium besylate
  • United States LKT Laboratories, Inc [Manufacturer]
  • Tel: (888)-558-5227
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64228-81-5 Atracurium Besylate

  • Atracurium Besylate
  • India J.INC. [Manufacturer]
  • Tel: +91 79 30071152, 30071190, 30071175, 30071153
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  • Address: # 95, Rangwala Towers, Law garden, Ellisbridge, Ahmedabad 380006, Gujarat State, India. 380006 AhmedabadINDIA Ahmedabad,nullIndia
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64228-81-5 Atracurium Besylate

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  • Address: wenzhou, China Wenzhou,ZhejiangChina
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64228-81-5 Atracurium Besilate

  • Atracurium Besilate, 99%min
  • China Shanghai Everchem Co.,Ltd. [Manufacturer]
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  • Address: No.277 Zheqiao Road,
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64228-81-5 ATRACURIUM BESYLATE

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64228-81-5 Atracurium Besylate

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64228-81-5 ATRACURIUM BESYLATE

  • China Ancheng Pharma Limited [Manufacturers]
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  • Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China Shenzhen,guangdongChina
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References of benzenesulfonate
Title: Atracurium Besylate
CAS Registry Number: 64228-81-5
CAS Name: 2,2￠-[1,5-Pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium] dibenzenesulfonate
Synonyms: 2-(2-carboxyethyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratrylisoquinolinium benzenesulfonate pentamethylene ester; N,N￠-dimethyl-N,N￠-(4,10-dioxa-3,11-dioxotridecylene)-1,13-bis-tetrahydropapaverinium dibesylate
Manufacturers' Codes: BW-33A; Wellcome 33-A-74
Trademarks: Tracrium (GSK)
Molecular Formula: C65H82N2O18S2
Molecular Weight: 1243.48
Percent Composition: C 62.78%, H 6.65%, N 2.25%, O 23.16%, S 5.16%
Literature References: Benzylisoquinolinium, competitive neuromuscular blocker. Prepn: J. B. Stenlake et al., DE 2655883; eidem, US 4179507 (1977, 1979 both to Burroughs Wellcome). Pharmacology: R. Hughes, D. J. Chapple, Br. J. Anaesth. 53, 31 (1981). Clinical pharmacology: S. J. Basta et al., Anesth. Analg. 61, 723 (1982). Neuromuscular effects in man: R. L. Katz et al., ibid. 730. Metabolic studies: E. A. Neill, D. J. Chapple, Xenobiotica 12, 203 (1982). Pharmacokinetics: S. Ward et al., Br. J. Anaesth. 55, 113 (1983). Use during halothane anesthesia in humans: J. A. Stirt et al., Anesth. Analg. 62, 207 (1983). Symposium on pharmacology, metabolism, and clinical studies: Br. J. Anaesth. 55, Suppl. 1, 1S-139S (1983); on pharmacokinetics and clinical experience: ibid. 58, Suppl. 1, 1S-113S (1986).
Properties: Off-white powder, mp 85-90°. Softens at 60°.
Melting point: mp 85-90°
 
Derivative Type: Cisatracurium besylate
CAS Registry Number: 96946-42-8
CAS Name: (1R,1￠R,2R,2￠R)-2,2￠-[1,5-Pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium] dibenzenesulfonate
Manufacturers' Codes: 51W89
Trademarks: Nimbex (GSK)
Literature References: Prepn: D. A. Hill, G. L. Turner, WO 9200965 (1992 to Wellcome Found.). Clinical pharmacology: C. A. Lien et al., Anesthesiology 82, 1131 (1995); M. R. Belmont et al., ibid. 1139.
Properties: White solid.
 
Therap-Cat: Neuromuscular blocking agent.
Therap-Cat-Vet: Neuromuscular blocking agent.
Keywords: Neuromuscular Blocking Agent; Nondepolarizing Agents.