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CAS No 65-45-2 , 2-hydroxybenzamide

  • Name: 2-hydroxybenzamide
  • Synonyms: Algamon; 65-45-2; Algiamida; 2-Carbamoylphenol; o-Hydroxybenzamide;2-hydroxybenzamide; 2-hydroxy-;2-Hydroxybenzamide; Salicylic acid amide; Benzamide;
  • CAS Registry Number:
  • Transport: 3249
  • Melting Point: 139-142 ºC
  • Boiling Point: 270 ºC
  • Density: 1,175 g/cm3
  • Refractive index: 1.562 (20 C)
  • Water Solubility: <0.1 G/100 ML AT 20 ºC
  • Safety Statements: R22
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 200-609-3
  • Molecular Weight: 137.13598
  • InchiKey: SKZKKFZAGNVIMN-UHFFFAOYSA-N
  • InChI: InChI=1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
  • Risk Statements: 26-36,
  • Molecular Formula: C7H7NO2
  • Molecular Structure:CAS No:65-45-2 2-hydroxybenzamide

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References of 2-hydroxybenzamide
Title: Salicylamide
CAS Registry Number: 65-45-2
CAS Name: 2-Hydroxybenzamide
Trademarks: Salamid (Hamilton); Samid (Knoll); Cidal (CID); Salizell (Byk Gulden); Salymid (Biochemie); Urtosal (Lifepharma)
Molecular Formula: C7H7NO2
Molecular Weight: 137.14
Percent Composition: C 61.31%, H 5.14%, N 10.21%, O 23.33%
Literature References: Prepn: A. Cahours, Ann. 48, 60 (1843); D. S. Hoffenberg, C. R. Hauser, J. Org. Chem. 20, 1496 (1955); J. B. Chattopadhyaya, A. V. Rama Rao, Tetrahedron 30, 2899 (1974). Toxicity data: Hart, J. Pharmacol. Exp. Ther. 89, 205 (1947). Clinical efficacy in headache: W. J. Murray, J. Clin. Pharmacol. J. New Drugs 7, 150 (1967). Pharmacokinetics: A. G. de Boer et al., Biopharm. Drug Dispos. 4, 321 (1983).
Properties: White or slightly pink, crystalline powder, somewhat bitter taste. Sensation of warmth on tongue. mp 140°. Soly in water at 30° = 0.2%, at 47° = 0.8%; in glycerol at 5° = 2.0%, at 39° = 5.0%, at 60° = 10.0%; in propylene glycol at 5° = 10.0%. Sol in hot water, alcohol, chloroform, ether. pH of satd aq soln at 28° about 5. Forms a water-soluble sodium salt at pH 9. LD50 orally in mice: 1.4 g/kg (Hart).
Melting point: mp 140°
Toxicity data: LD50 orally in mice: 1.4 g/kg (Hart)
Therap-Cat: Analgesic.
Keywords: Analgesic (Non-Narcotic).