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CAS No 65-49-6 , 4-amino-2-hydroxybenzoic acid Search by region : China

  • Name: 4-amino-2-hydroxybenzoic acid
  • Synonyms: Aminopar; Pamisyl; 4-Amino-2-hydroxybenzoic acid; Aminosalicylic acid;4-amino-2-hydroxybenzoic acid;4-Aminosalicylic acid; Ferrosan; Rezipas; P-AMINOSALICYLIC ACID; Deapasil;
  • CAS Registry Number:
  • Transport: UN 1789 8/PG 3
  • Melting Point: 135-145 ºC
  • Boiling Point: 347
  • Density: 1.545 g/cm3
  • Water Solubility: 2 G/L (20 ºC)
  • Safety Statements: R36/37/38
  • Hazard Symbols: Xi: Irritant;
  • HS Code: 29225000
  • EINECS: 200-613-5
  • Molecular Weight: 153.13538
  • InchiKey: WUBBRNOQWQTFEX-UHFFFAOYSA-N
  • InChI: InChI=1S/C7H7NO3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,9H,8H2,(H,10,11)
  • Risk Statements: S26;S37/39
  • Molecular Formula: C7H7NO3
  • Molecular Structure:CAS No:65-49-6 4-amino-2-hydroxybenzoic acid

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65-49-6 99% Feed Grade White Powder Erythromycin Thiocyanate

  • 99% Feed Grade White Powder Erythromycin Thiocyanate Key words:Aminosalicylic acid,CAS: 65-49-6,pharmaceutical *.Basic info: product name: Aminosalicylic acid English name: 4-Amino Salicylic Acid Alias: 4- amino -2- hydroxy benzoic acid CAS: 65-49-6 ...
  • Min. Order: 1000
  • FOB Price: USD1 - 2 /
  • China Wuhan Yuancheng Technology Development Co.,Ltd [Manufacturer]
  • Tel: 86-027-68886696
  • Address: No. 496 Zhongshan Road, Wuchang District wuhan,HubeiChina
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65-49-6 4-Aminosalicylic acid

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
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65-49-6 4-Aminosalicylic acid

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65-49-6 4-Aminosalicylic acid

  • China Hangzhou Sage Chemical Co., Ltd. [Manufacturer]
  • Tel: +86-571-86818502
  • Fax: +86-571-86818503
  • Address: RM501 Tower A, New Youth Plaza, NO.8 Jia Shan Road, Hangzhou, Zhejiang 310014, null,ZhejiangChina
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65-49-6 4-aminosalicyclic acid

  • 4-aminosalicyclic acid4-aminosalicyclic acid, 98%
  • China PMIDA AGROCHEMICAL CO.,LTD [Manufacturer]
  • Tel: +86-023-67030808-8010
  • Fax: +86-023-67030809
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone401121 ChongqingCHINA Chongqing,nullChina
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65-49-6 4-Aminosalicyclic acid

  • 4-Aminosalicyclic acid, 98%
  • China Shanghai Rainbow Chemistry Co., Ltd. [Manufacturer]
  • Tel: +86-21-64968086
  • Fax: +86-21-64968086
  • Address: Room 128, Building B, No. 8 Lane 1305, Huajing Road, Xuhui District, Shanghai, P.R. China 200000 Shanghai CHINA Shanghai,nullChina
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65-49-6 4-Cyanophenyl 4-heptylbenzoate

  • 4-Cyanophenyl 4-heptylbenzoate
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,nullChina
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65-49-6 4-Aminosalicylic acid

  • 4-Aminosalicylic acid
  • China Shanghai Synnad Chemical Co., Ltd. [Importer/Exporter]
  • Tel: 86 21 5109 7911
  • Fax: 86 21 5109 7955
  • Address: B-5 Ecust Science Park, No. 18, Lane 1305, Hua Jing Road, Shanghai 200231 China Shanghai,ShanghaiChina
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65-49-6 4-Aminosalicylic acid

  • China ORCHID CHEMICAL SUPPLIES LTD (OCS) [Importer/Exporter]
  • Tel: +86-571-85395792
  • Fax: +86-571-85420103
  • Address: 607, North Zhongshan Road, Hangzhou 310000 China null,ZhejiangChina
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65-49-6 4-Aminosalicylic Acid, 98%

  • 4-Aminosalicylic Acid, 98%
  • China Changchem [Manufacturer]
  • Tel: +86 513 8515 5236
  • Fax: +86 513 8515 2292
  • Address: 7th Floor76 Yue Long Road226001 Nantong null,nullChina
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References of 4-amino-2-hydroxybenzoic acid
Title: p-Aminosalicylic Acid
CAS Registry Number: 65-49-6
CAS Name: 4-Amino-2-hydroxybenzoic acid
Synonyms: 4-aminosalicylic acid; PAS
Trademarks: PASER (Jacobus); Rezipas (BMS)
Molecular Formula: C7H7NO3
Molecular Weight: 153.14
Percent Composition: C 54.90%, H 4.61%, N 9.15%, O 31.34%
Literature References: Prepn: DE 50835 (1889); US 427564 (1890); Sheehan, J. Am. Chem. Soc. 70, 1665 (1948); Erlenmeyer et al., Helv. Chim. Acta 31, 988 (1948); Wenis, Gardner, J. Am. Pharm. Assoc. 38, 9 (1949); Centolella, US 2844625 (1958 to Miles). Toxicity study: E. M. Bavin et al., J. Pharm. Pharmacol. 2, 764 (1950). Comprehensive description: M. M. A. Hassan et al., Anal. Profiles Drug Subs. 10, 1-27 (1981).
Properties: Minute crystals from alcohol, mp 150-151° with effervescence. uv max (0.1N HCl): 265, 300 nm. pKa 3.25. pH of 0.1% aq soln: 3.5. One gram dissolves in about 500 ml water, in 21 ml alcohol. Slightly sol in ether. Practically insol in benzene. Sol in dilute nitric acid, dil sodium hydroxide. At temps above 40°, aq solns of PAS and its hydrochloride are readily decarboxylated to give brown solns consisting mainly of m-aminophenol. LD50 orally in mice: 4 g/kg (Bavin).
Melting point: mp 150-151° with effervescence
pKa: pKa 3.25
Absorption maximum: uv max (0.1N HCl): 265, 300 nm
Toxicity data: LD50 orally in mice: 4 g/kg (Bavin)
 
Derivative Type: Hydrochloride
Molecular Formula: C7H7NO3.HCl
Molecular Weight: 189.60
Percent Composition: C 44.34%, H 4.25%, N 7.39%, O 25.32%, Cl 18.70%
Properties: Crystals, dec 224°.
 
Derivative Type: Sodium salt dihydrate
CAS Registry Number: 6018-19-5
Trademarks: Aminacyl (Wander); Nemasol Sodium (Valeant); Pamisyl Sodium (Parke-Davis); Paramisan Sodium (Smith & Nephew); Pasalon (Bayer)
Molecular Formula: C7H6NNaO3.2H2O
Molecular Weight: 211.15
Percent Composition: C 39.82%, H 4.77%, N 6.63%, Na 10.89%, O 37.89%
Properties: pH of 1% soln ~7. One gram dissolves in 2 ml water. Very sparingly sol in acetone. Practically insol in ether, chloroform, benzene. Solns of the sodium salt are more resistant to heat than PAS, but sterilization by bacterial filtration is recommended.
 
Derivative Type: Calcium salt
CAS Registry Number: 133-15-3
Trademarks: Nippas Calcium (Tanabe)
Molecular Formula: C14H12CaN2O6
Molecular Weight: 344.33
Percent Composition: C 48.83%, H 3.51%, Ca 11.64%, N 8.14%, O 27.88%
Properties: Bittersweet crystals. One gram dissolves in about 7 ml water, slightly sol in alc. Aq solns dec slowly and darken in color.
 
Derivative Type: Potassium salt
CAS Registry Number: 133-09-5
Trademarks: Paskalium (Glenwood)
Molecular Formula: C7H6NO3K
Molecular Weight: 191.23
Percent Composition: C 43.97%, H 3.16%, N 7.32%, O 25.10%, K 20.45%
Properties: Crystals, freely sol in water. pH of 1% soln about 7. Reported to cause less gastric irritation than the free acid or the sodium salt.
 
Derivative Type: Ethyl ester
Molecular Formula: C9H11NO3
Molecular Weight: 181.19
Percent Composition: C 59.66%, H 6.12%, N 7.73%, O 26.49%
Properties: Needles from alc, mp 115°. Prepd by reduction of the ethyl ester of 4-nitrosalicylic acid.
Melting point: mp 115°
 
Derivative Type: Phenyl ester see Phenyl Aminosalicylate
 
Therap-Cat: Antibacterial (tuberculostatic).
Keywords: Antibacterial (Tuberculostatic).