Home > Name List By a > Aescine China

CAS No 6805-41-0 , Aescine Search by region : China

  • Name: Aescine
  • Synonyms: Aescine;Escin; Aescin; Chestnuts extract;
  • CAS Registry Number:
  • Density: 1.46 g/cm3
  • Refractive index: 1.627
  • Safety Statements: 22-24/25
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 229-880-6
  • Molecular Weight: 1131.26
  • InChI: InChI=1/2C55H86O24/c2*1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(19-56)73-47/h2*10-11,26-44,47-49,56-59,61-68H,12-22H2,1-9H3,(H,69,70)/b23-10+;23-10-/t2*26?,27-,28-,29?,30?,31-,32?,33-,34-,35+,36+,37-,38-,39+,40+,41-,42+,43+,44+,47+,48+,49-,51+,52-,53-,54-,55+/m11/s1
  • Risk Statements: 22-20/22
  • Molecular Formula: C55H86O24
  • Molecular Structure:CAS No:6805-41-0 Aescine

Related products

Select to

6805-41-0 Escin

  • Escin Name: Escin Synonym: BETA-AESCIN;ESCIN;Chestnuts extract;AESCIN;(2S,3S,4S,5R,6R)-6-[[(3S,4R,4aR,6aR,6bS,8R,8aS,9S,10S,12aR,14aR,14bS)-9-Acetyloxy-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(Z)-2-methylbut-2-enoyl]oxy-1,2...
  • China Yuan Cheng GongChuang Technology Co., Ltd. [Manufacturer, Trading Company]
  • Tel: 86-188-72220762
  • Address: No.496,Zhongshan Road,Wuchang District WUHAN,HubeiChina
Contact Supplier

6805-41-0 Escin

  • Escin Name: Escin Synonym: BETA-AESCIN;ESCIN;Chestnuts extract;AESCIN;(2S,3S,4S,5R,6R)-6-[[(3S,4R,4aR,6aR,6bS,8R,8aS,9S,10S,12aR,14aR,14bS)-9-Acetyloxy-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(Z)-2-methylbut-2-enoyl]oxy-1,2...
  • Min. Order: 1
  • FOB Price: USD0.7 - 10000 /
  • China HB Yuancheng [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 86-027-87789968
  • Address: Zhongshan Road Wuhan,HubeiChina
Contact Supplier

6805-41-0 Escin

  • Escin Synonym: BETA-AESCIN;ESCIN;Chestnuts extract;AESCIN;(2S,3S,4S,5R,6R)-6-[[(3S,4R,4aR,6aR,6bS,8R,8aS,9S,10S,12aR,14aR,14bS)-9-Acetyloxy-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(Z)-2-methylbut-2-enoyl]oxy-1,2,3,4a,5,6,7,...
  • Min. Order: 500
  • China Wuhan Yuancheng Group [Manufacturer, Trading Company]
  • Tel: 86-027-50756153
  • Address: Zhongshan Road Wuhan,HubeiChina
Contact Supplier

6805-41-0 Horse Chestnut Extract

  • Horse Chestnut Extract Type: Herbal Extract Latin name: Aesculus chinesis Bge Origin: China Part: Fruit or Seed Color: Brown Yellow Form: Powder BSE/TSE: Free Active Ingredient: Escin CAS: 6805-41-0 MF: C55H86O24 MW: 1131.26 EINECS: 229-880-6 Assay: ...
  • Min. Order: 500
  • China Wuhan Yuancheng Group [Manufacturer, Trading Company]
  • Tel: 86-027-50756153
  • Address: Zhongshan Road Wuhan,HubeiChina
Contact Supplier

6805-41-0 Escin

  • Name: Escin Synonym: BETA-AESCIN;ESCIN;Chestnuts extract;AESCIN;(2S,3S,4S,5R,6R)-6-[[(3S,4R,4aR,6aR,6bS,8R,8aS,9S,10S,12aR,14aR,14bS)-9-Acetyloxy-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(Z)-2-methylbut-2-enoyl]oxy-1,2,3,4a,...
  • Min. Order: 3000
  • China Wuhan Yuancheng Gongchuang Technology Co.Ltd [Manufacturer]
  • Tel: 86-27-50756085
  • Fax: --
  • Address: No.496, Wuchang District, wuhan,HubeiChina
Contact Supplier

6805-41-0 Escin(aescin) Chestnuts extract

  • Escin(aescin) Chestnuts extractEscin(aescin) Chestnuts extract, 98%
  • China PMIDA AGROCHEMICAL CO.,LTD [Manufacturer]
  • Tel: +86-023-67030808-8010
  • Fax: +86-023-67030809
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone401121 ChongqingCHINA Chongqing,nullChina
Contact Supplier

6805-41-0 Escin(aescin) chestnuts extract

  • Escin(aescin) chestnuts extract, 98%
  • China Shanghai Rainbow Chemistry Co., Ltd. [Manufacturer]
  • Tel: +86-21-64968086
  • Fax: +86-21-64968086
  • Address: Room 128, Building B, No. 8 Lane 1305, Huajing Road, Xuhui District, Shanghai, P.R. China 200000 Shanghai CHINA Shanghai,nullChina
Contact Supplier

6805-41-0 Aescin

  • Aescin, 99,00%
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,nullChina
Contact Supplier

6805-41-0 Aescin

  • Aescin
  • China Shanghai Synnad Chemical Co., Ltd. [Importer/Exporter]
  • Tel: 86 21 5109 7911
  • Fax: 86 21 5109 7955
  • Address: B-5 Ecust Science Park, No. 18, Lane 1305, Hua Jing Road, Shanghai 200231 China Shanghai,ShanghaiChina
Contact Supplier

6805-41-0 Aescine

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China null,ZheJiangChina
Contact Supplier

Select to

References of Aescine
Title: Escin
CAS Registry Number: 6805-41-0
Synonyms: Aescin
Trademarks: Reparil (Madaus)
Literature References: A mixture of saponins occurring in the seed of the horse chestnut tree, Aesculus hippocastanum L., Hippocastanaceae: Winterstein, Z. Physiol. Chem. 199, 25 (1931); Steiner, Holtzem in Paech-Tracey, Moderne Methoden der Pflanzenanalyse III (Springer-Verlag, 1955) p 117. Isoln by chromatography and purification: Fiedler, Arzneim.-Forsch. 4, 213 (1953); using ion-exchange resins: Erbring et al., US 3238190 (1966 to Madaus). Previously thought to be built up from the aglycon escigenin, glucuronic acid, glucose and xylose: Jermstadt, Waaler, Pharm. Acta Helv. 28, 265 (1953); Patt, Winkler, Arzneim.-Forsch. 10, 273 (1960); Tschesche et al., Ann. 669, 171 (1963). Structural studies indicate that the two major glycosides in the mixture are built up from the aglycon, protoescigenin, which is acylated at C-22 by acetic acid, and from the sugar moiety, glucuronic acid and two D-glucose molecules. The two aglycons differ only at the C-21 position which is acylated by either angelic acid or tiglic acid, q.q.v. Structure and stereochemistry: Wulff, Tschesche, Tetrahedron 25, 415 (1969); Wagner et al., Arzneim.-Forsch. 20, 205 (1970); eidem, Z. Physiol. Chem. 351, 1133 (1970). Early work identified two forms, a-escin and b-escin: Wagner, Basse, ibid. 320, 27 (1960). Identity of prosaponin B with b-escin: Voigtlander, Rosenberg, Arzneim.-Forsch. 13, 385 (1963). b-Escin is the natural form and can be converted to a-escin: Wagner, Schlemmer, US 3450691 (1969 to Klinge); Wagner et al., Arzneimittel-Forsch., loc. cit. Pharmacology: H. Hampel et al., ibid. 20, 209 (1970); Lang, Mennicke, ibid. 22, 1928 (1972). Review: Tschesche, Wulff in Fortschr. Chem. Org. Naturst. 30, 461-606 (1973). Review of pharmacology and clinical experience: C. R. Sirtori, Pharmacolog. Res. 44, 183-193 (2001).
 
Derivative Type: a-Escin
CAS Registry Number: 66795-86-6
Properties: Amorphous powder, mp 225-227°. [a]D25 -13.5° (c = 5 in methanol). Very sol in water. Hemolytic index: 1:20,000. LD50 in mice, rats, guinea pigs (mg/kg): 3.2, 5.4, 15.2 i.v.; 320, 720, 475 orally (Hampel).
Melting point: mp 225-227°
Optical Rotation: [a]D25 -13.5° (c = 5 in methanol)
Toxicity data: LD50 in mice, rats, guinea pigs (mg/kg): 3.2, 5.4, 15.2 i.v.; 320, 720, 475 orally (Hampel)
 
Derivative Type: Sodium salt
Properties: mp 251-252°.
Melting point: mp 251-252°
 
Derivative Type: b-Escin
CAS Registry Number: 11072-93-8
Trademarks: Flogencyl (Expanpharm)
Properties: Leaflets from dil ethanol, mp 222-223°. [a]D27 -23.7° (c = 5 in methanol). Practically insol in water. Hemolytic index: 1:40,000. LD50 in mice, rats, guinea pigs (mg/kg): 1.4, 2.0, 7.2 i.v.; 134, 400, 188 orally (Hampel).
Melting point: mp 222-223°
Optical Rotation: [a]D27 -23.7° (c = 5 in methanol)
Toxicity data: LD50 in mice, rats, guinea pigs (mg/kg): 1.4, 2.0, 7.2 i.v.; 134, 400, 188 orally (Hampel)
 
Therap-Cat: In treatment of peripheral vascular disorders.
Keywords: Vasoprotectant.