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CAS No 69123-98-4 , Fialuridine Search by region : Germany

  • Name: Fialuridine
  • Synonyms: Fialuridine;1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione;
  • CAS Registry Number:
  • Density: 2.18 g/cm3
  • Refractive index: 1.685
  • Molecular Weight: 372.09
  • InChI: InChI=1/C9H10FIN2O5/c10-5-6(15)4(2-14)18-8(5)13-1-3(11)7(16)12-9(13)17/h1,4-6,8,14-15H,2H2,(H,12,16,17)
  • Molecular Formula: C9H10FIN2O5
  • Molecular Structure:CAS No:69123-98-4 Fialuridine

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69123-98-4 2910 FIAU

  • Germany ABX advanced biochemical compounds GmbH [Manufacturer]
  • Tel: + 49 / 35 28 / 40 41 60
  • Fax: + 49 / 35 28 / 40 41 65
  • Address: ABX advanced biochemical compounds GmbH
    Heinrich-Glaeser-Strasse 10 - 14
    D - 01454 Radeberg, Germany null,nullGermany
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References of Fialuridine
Title: Fialuridine
CAS Registry Number: 69123-98-4
CAS Name: 1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione
Synonyms: 1-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-5-iodouracil; 5-iodo-2￠-fluoroarauracil; FIAU
Molecular Formula: C9H10FIN2O5
Molecular Weight: 372.09
Percent Composition: C 29.05%, H 2.71%, F 5.11%, I 34.11%, N 7.53%, O 21.50%
Literature References: Exptl antiviral agent; nucleoside analog with antihepatitis B activity. Prepn: K. A. Watanabe et al., J. Med. Chem. 22, 21 (1979). Antiviral activity: J. M. Colacino, C. Lopez, Antimicrob. Agents Chemother. 24, 505 (1983); K. A. Staschke et al., Antiviral Res. 23, 45 (1994). Clinical pharmacokinetics: R. R. Bowsher et al., Antimicrob. Agents Chemother. 38, 2134 (1994). Report of trial suspension: S. R. Ahmed, Lancet 342, 166 (1993). Evaluation of mechanism of hepatotoxicity: L. Cui et al., J. Clin. Invest. 95, 555 (1995). Clinical toxicological profile: W. Stevenson et al., Transplant. Proc. 27, 1219 (1995).
Properties: Crystals from ethanol, mp 216-217°.
Melting point: mp 216-217°