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CAS No 71751-41-2 , ABAMECTIN

  • Name: ABAMECTIN
  • Synonyms: DYNAMEC;ACIMIC;ABAMECTIN; ABACIDE; BERMECTINE; avermectin B1b; avermectin B1a; ABAMECTINE; AVERMECTIN B1; DYNAMEC(R); AVERMECTIN B;
  • CAS Registry Number:
  • Transport: 2588
  • Density: 1.16
  • Water Solubility: insoluble
  • Safety Statements: 36/37/39-45-60-61
  • Hazard Symbols: T+,N
  • EINECS: 265-610-3
  • Molecular Weight: (873.09);(859.06)
  • InChI: InChI=1/C48H72O14.C47H70O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38;1-24(2)41-27(5)16-17-46(61-41)22-33-19-32(60-46)15-14-26(4)42(25(3)12-11-13-31-23-54-44-39(48)28(6)18-34(45(50)57-33)47(31,44)51)58-38-21-36(53-10)43(30(8)56-38)59-37-20-35(52-9)40(49)29(7)55-37/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3;11-14,16-18,24-25,27,29-30,32-44,48-49,51H,15,19-23H2,1-10H3/b13-12+,27-15+,32-14+;12-11+,26-14+,31-13+/t25-,26+,28+,30+,31+,33-,34+,35+,36+,37+,38+,39+,40-,41+,42+,43-,44+,45-,47-,48-;25-,27-,29-,30-,32+,33-,34-,35-,36-,37-,38-,39+,40-,41+,42-,43-,44+,46+,47+/m10/s1
  • Risk Statements: 20-28-50
  • Molecular Formula: C48H72O14;C47H70O14
  • Molecular Structure:CAS No:71751-41-2 ABAMECTIN
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71751-41-2 Avermectin B

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71751-41-2 Abamectin

  • China Hangzhou Yilong Chemical Industry Co., Ltd. [Importer/Exporter]
  • Tel: 0086-571-87214516
  • Fax: 86-571-87079476
  • Address: Room 1806,Block 1,Hangtian TongXun Tower,No. 138 Jiefang Road, Hangzhou, China Hangzhou,zhejiangChina
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71751-41-2 ABAMECTIN

  • China Shanghai Mingdou Chemical Co.,Ltd [Manufacturers]
  • Tel: 86-21-52912919
  • Fax: 021-52912097
  • Address: Floor 12th, Zhenyuan Building ,No 2052.North Zhongshan Road, Shanghai,China null,shanghaiChina
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71751-41-2 ABAMECTIN

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71751-41-2 Abamectin

  • China IFFECT CHEMPHAR CO., LTD. null
  • Tel: 0086 755-83761619 83760606
  • Fax: +86-25- 84270111
  • Address: 15A,Changfa Center, Building B ,No. 300,East Zhongshan Road,Baixia District,Nanjing,210002, P.R.China. Nanjing,JiangshuChina
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71751-41-2 Abamectin

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71751-41-2 ABAMECTIN

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71751-41-2 ABAMECTIN

  • China NINGBO AGRO-STAR INDUSTRIAL CO., LTD. [Manufacturers]
  • Tel: 86-574-87267018, 87267336
  • Fax: 0574-87267116
  • Address: Rm 412,No.43 Liuzhuangxiang,city plaza,Haishu District,Ningbo,China. Ningbo,zhejiangChina
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71751-41-2 Abamectin

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71751-41-2 Avermectin B1

  • China Nanjing General Chemical Co., Ltd. [Manufacturers]
  • Tel: +86-(25)-8319-0965
  • Fax: +86-(25)-8319-0349
  • Address: 15/F HuijieMansion, 268 Zhongshan Road, Nanjing, Jiangsu 210008, Nanjing,JiangsuChina
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References of ABAMECTIN
Title: Abamectin
CAS Registry Number: 71751-41-2
CAS Name: Avermectin B1
Synonyms: 5-O-demethylavermectin A1a and 5-O-demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)avermectin A1a (4:1); avermectin B1a/b
Manufacturers' Codes: MK-936
Trademarks: Agri-Mek (Syngenta); Avid (Syngenta); Zephyr (Syngenta)
Literature References: Mixture of avermectins, q.v., containing at least 80% of avermectin B1a (C48H72O14) and not more than 20% of avermectin B1b (C47H70O14). Isoln from Streptomyces avermitilis: G. Albers-Sch?nberg et al., DE 2717040; eidem, US 4310519 (1977, 1982 both to Merck & Co.). Separation of components: T. W. Miller et al., Antimicrob. Agents Chemother. 15, 368 (1979); by semi-preparative HPLC: C. C. Ku et al., J. Liq. Chromatogr. 7, 2905 (1984). Structure determn: G. Albers-Sch?nberg et al., J. Am. Chem. Soc. 103, 4216 (1981). Absolute configuration: J. P. Springer et al., ibid. 4221. Partial synthesis of B1a: K. C. Nicolaou et al., ibid. 106, 4189 (1984). Total synthesis: S. Hanessian et al., ibid. 108, 2776 (1986). Anthelmintic activity: L. S. Blair, W. C. Campbell, J. Parasitol. 64, 1032 (1978); J. R. Egerton et al., Antimicrob. Agents Chemother. 15, 372 (1979); K. S. Todd et al., Am. J. Vet. Res. 45, 976 (1984). Pesticidal activity: I. Putter et al., Experientia 37, 963 (1981); R. A. Dybas, A. St. J. Green, Proc. Br. Crop Prot. Conf. - Pests Dis. 1984, 947. Control of red imported fire ants: J. A. Greenblatt et al., J. Agric. Entomol. 3, 233 (1986). Interaction with GABA receptors: S. S. Pong et al., J. Neurochem. 34, 351 (1980); T. N. Mellin et al., Neuropharmacology 22, 89 (1983). Receptor binding studies: S. S. Pong, C. C. Wang, ibid. 19, 311 (1980); G. Drexler, W. Sieghart, Eur. J. Pharmacol. 99, 269 (1984). Fate in soil and plants: D. L. Bull et al., J. Agric. Food Chem. 32, 94 (1984); H. A. Moye et al., ibid. 35, 859 (1987); M. S. Maynard et al., ibid. 37, 178, 184 (1989). Review: J. R. Babu, ACS Symp. Ser. 380, 91-108 (1988). Reviews of modes of action: C. C. Wang, S. S. Pong, Prog. Clin. Biol. Res. 97, 373-395 (1982); D. J. Wright, Biochem. Soc. Trans. 15, 65-67 (1987); of insecticidal activities and use: L. Strong, T. A. Brown, Bull. Entomol. Res. 77, 357-389 (1987). Book: Ivermectin and Abamectin, W. C. Campbell, Ed. (Springer-Verlag, New York, 1989) 363 pp.
Properties: Odorless, off-white to yellow crystals from methanol, mp 150-155° (dec). [a]D +55.7 ±2° (c = 0.87 in CHCl3). uv max (methanol): 237, 245, 253 nm (log e 4.48, 4.53, 4.34). Vapor pressure: 1.5 ′ 10-9 torr. Soly at 21° (mg/l): water 10; (mg/ml): acetone 100; n-butanol 10; chloroform 25; cyclohexane 6; ethanol 20; isopropanol 70; kerosene 0.5; methanol 19.5; toluene 350. Hydrolysis does not occur in aq soln at pH 3, 5, 7. LD50 (technical grade) orally in sesame oil in mouse, rat: 13.5, 10.0 mg/kg; dermally in rabbit: >2000 mg/kg. LD50 in mallard duck, bobwhite quail: 84.6, >2000 mg/kg. LC50 (96 hr) in rainbow trout, bluegill: 3.6, 9.6 mg/l; LC50 (48 hr) in Daphnia magna: 0.34 mg/l (Merck Technical Data Sheet).
Melting point: mp 150-155° (dec)
Optical Rotation: [a]D +55.7 ±2° (c = 0.87 in CHCl3)
Absorption maximum: uv max (methanol): 237, 245, 253 nm (log e 4.48, 4.53, 4.34)
Toxicity data: LD50 (technical grade) orally in sesame oil in mouse, rat: 13.5, 10.0 mg/kg; dermally in rabbit: >2000 mg/kg; LD50 in mallard duck, bobwhite quail: 84.6, >2000 mg/kg; LC50 (96 hr) in rainbow trout, bluegill: 3.6, 9.6 mg/l; LC50 (48 hr) in Daphnia magna: 0.34 mg/l (Merck Technical Data Sheet)
Use: Acaricide; insecticide.
Therap-Cat-Vet: Anthelmintic.