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CAS No 73-24-5 , 7H-purin-6-amine Search by region : Belgium

  • Name: 7H-purin-6-amine
  • Synonyms: 9H-Purin-6-amine; 1H-Purin-6-amine; 73-24-5; Leuco-4;6-Aminopurine; 6-Amino-1H-purine;7H-purin-6-amine; Adenin; Vitamin B4; Adeninimine;
  • CAS Registry Number:
  • Transport: HAZARD
  • Melting Point: 360-365 ºC
  • Density: 1.612 g/cm3
  • Refractive index: 1.954
  • Water Solubility: 0.5 G/L (20 ºC)
  • Safety Statements: R22
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 200-796-1
  • Molecular Weight: 135.1267
  • InchiKey: GFFGJBXGBJISGV-UHFFFAOYSA-N
  • InChI: InChI=1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)
  • Risk Statements: S26;S36
  • Molecular Formula: C5H5N5
  • Molecular Structure:CAS No:73-24-5 7H-purin-6-amine

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73-24-5 Adenine, 99%

  • Adenine, 99%
  • Belgium Alkemi [Manufacturer]
  • Tel: +32 9 340 49 49
  • Fax: +32 9 340 49 47
  • Address: Poststraat, 82 B-9160 Lokeren Belgium ,Belgium
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References of 7H-purin-6-amine
Title: Adenine
CAS Registry Number: 73-24-5
CAS Name: 1H-Purin-6-amine
Synonyms: 6-aminopurine; 6-amino-1H-purine; 6-amino-3H-purine; 6-amino-9H-purine; 1,6-dihydro-6-iminopurine; 3,6-dihydro-6-iminopurine
Trademarks: Leuco-4
Molecular Formula: C5H5N5
Molecular Weight: 135.13
Percent Composition: C 44.44%, H 3.73%, N 51.83%
Literature References: Also referred to as vitamin B4: Lecoq, Int. Z. Vitaminforsch. 27, 291 (1957). Widespread throughout animal and plant tissues combined with niacinamide, D-ribose, and phosphoric acids; a constituent of nucleic acids and coenzymes, such as codehydrase I and II, adenylic acid, coalaninedehydrase. Isoln from bovine pancreas: Kossel, Ber. 18, 79, 1928 (1885). Syntheses: Fischer, ibid. 30, 2226 (1897); Traube, Ann. 331, 64 (1904); Hoffer, Jubilee Vol. Emil Barell 1946, 428-434; Taylor et al., Ciba Found. Symp. Chem. Biol. Purines 1957, 20, C.A. 53, 6238b (1959); Bredereck et al., Angew. Chem. 71, 524 (1959); Morita et al., Chem. Ind. (London) 1968, 1117; Sekiya, Suzuki, Chem. Pharm. Bull. 20, 209 (1972); N. J. Kos et al., J. Org. Chem. 44, 3140 (1979). Toxicity study: Philips et al., J. Pharmacol. Exp. Ther. 104, 20 (1952). Review: Ts'o, "Bases, Nucleosides and Nucleotides" in Basic Principles in Nucleic Acid Chemistry vol. 1, P. O. P. Ts'o, Ed. (Academic Press, New York, 1974) pp 453-584.
Properties: Trihydrate, orthorhombic needles. Anhydr at 110°, dec 360-365°, subl 220°. uv max (pH 7.0): 207, 260.5 nm (e ′ 10-3 23.2, 13.4). One gram of anhydr compd dissolves in 2000 ml water, 40 ml boiling water; slightly sol in alc. Practically insol in ether, CHCl3. Aq solns are neutral. Combines with acids and bases. LD50 orally in rats: 745 mg/kg (Philips).
Absorption maximum: uv max (pH 7.0): 207, 260.5 nm (e ′ 10-3 23.2, 13.4)
Toxicity data: LD50 orally in rats: 745 mg/kg (Philips)
 
Derivative Type: Hydrochloride hemihydrate
Properties: Monoclinic prisms. One gram dissolves in 42 ml water.
 
Derivative Type: Sulfate dihydrate
Properties: Crystals. One gram dissolves in 150 ml water; slightly sol in alc.
 
Use: In microbial determination of niacin; in research on heredity, virus diseases, and cancer.