Home > Name List By 1 > 1-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-1, 4-diazepan-1-yl]butan-1-one Germany

CAS No 80755-51-7 , 1-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-1,
4-diazepan-1-yl]butan-1-one Search by region : Germany

  • Name: 1-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-1,
    4-diazepan-1-yl]butan-1-one
  • Synonyms: 80755-51-7; Bunazosinum [Latin]; Bunazosina [Spanish]; Bunazosin [INN];Bunazosine [French];1-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-1,
    4-diazepan-1-yl]butan-1-one; Bunazosin (INN);
  • CAS Registry Number:
  • Density: 1.221
  • Molecular Weight: 373.44938
  • InchiKey: RHLJLALHBZGAFM-UHFFFAOYSA-N
  • InChI: InChI=1S/C19H27N5O3/c1-4-6-17(25)23-7-5-8-24(10-9-23)19-21-14-12-16(27-
    3)15(26-2)11-13(14)18(20)22-19/h11-12H,4-10H2,1-3H3,(H2,20,21,22)
  • Molecular Formula: C19H27N5O3
  • Molecular Structure:CAS No:80755-51-7 1-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-1,<br />4-diazepan-1-yl]butan-1-one

Related products

Select to

80755-51-7 Bunazosin

  • Bunazosin
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
Contact Supplier

Select to

1/1
References of 1-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-1,
4-diazepan-1-yl]butan-1-one
Title: Bunazosin
CAS Registry Number: 80755-51-7
CAS Name: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)hexahydro-4-(1-oxobutyl)-1H-1,4-diazepine
Synonyms: 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-butyrylhexahydro-1H-1,4-diazepine; 4-amino-6,7-dimethoxy-2-[4-(n-butyryl)homopiperazin-1-yl]quinazoline; DDQ
Molecular Formula: C19H27N5O3
Molecular Weight: 373.45
Percent Composition: C 61.11%, H 7.29%, N 18.75%, O 12.85%
Literature References: Aminoquinazoline derivative with potent hypotensive properties. Prepn: T. Takahashi, H. Sugimoto, BE 806626; eidem, US 3920636 (1974, 1975 to Eisai); alternative prepn: eidem, JP Kokai 75 140474 (1975 to Eisai), C.A. 85, 46769r (1976). In vitro and in vivo studies of adrenergic blocking action and antihypertensive properties: T. Shoji et al., Jpn. J. Pharmacol. 30, 763 (1980); K. Hoshi, S. Fujino, ibid. 427. Antihypertensive effect in volunteers: T. Kawasaki et al., Eur. J. Clin. Pharmacol. 20, 399 (1981). Pharmacokinetics: C. Yamato et al., Xenobiotica 12, 549 (1982).
 
Derivative Type: Hydrochloride
CAS Registry Number: 52712-76-2
Manufacturers' Codes: E-643
Trademarks: Detantol (Eisai)
Molecular Formula: C19H27N5O3.HCl
Molecular Weight: 409.91
Percent Composition: C 55.67%, H 6.89%, N 17.09%, O 11.71%, Cl 8.65%
Properties: Crystals from methanol/ethanol, mp 280-282°.
Melting point: mp 280-282°
 
Therap-Cat: Antihypertensive.
Keywords: Antihypertensive; Quinazoline Derivatives.