Home > Name List By r > Riboflavin

CAS No 83-88-5 , Riboflavin

  • Name: Riboflavin
  • Synonyms: 7,8-Dimethyl-10-ribitylisoalloxazine; Vitamin B2; Vitamin B2 (Riboflavine); Riboflavine;Riboflavin; Vitamin B_2;Lactoflavine; Vitamin B2 Feed Grade; Lactoflavine; Riboflavin Vitamin B2; E 101; Riboflavin (1.07609);
  • CAS Registry Number:
  • Transport: 25kgs
  • Melting Point: 290 ºC
  • Density: 1.65
  • Refractive index: -135 ° (C=0.5, JP Method)
  • Alpha: -135 º (C=5, 0.05 M NAOH)
  • Water Solubility: 0.07 G/L (20 ºC)
  • Safety Statements: S24/25
  • HS Code: 29362300
  • EINECS: 201-507-1
  • Molecular Weight: 376.37
  • InChI: InChI=1/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m1/s1
  • Risk Statements: S24/25
  • Molecular Formula: C17H20N4O6
  • Molecular Structure:CAS No:83-88-5 Riboflavin
Search by region :

Select to

83-88-5 VITAMIN B2

  • China SINOCO CHEMICAL CO., LIMITED [Importer/Exporter]
  • Tel: +86-571-81956191, 81956192
  • Fax: 86-571-81956190 88386326
  • Address: 425 Ruiqi Mansion Moganshan Road , Hangzhou 310011 China. Hangzhou,ZhejiangChina
Contact Supplier

83-88-5 Riboflavin

Contact Supplier

83-88-5 RIBOFLAVIN BIOCHEMICA

  • Germany AppliChem GmbH [Manufacturer]
  • Tel: +49 6151 93 57 0
  • Fax: +49 6151 93 57 11
  • Address: AppliChem GmbH
    Ottoweg 4
    64291 Darmstadt
    Germany null,nullGermany
Contact Supplier

83-88-5 VITAMIN B2

  • China Unispec Chemicals Co. [Manufacturer]
  • Tel: +86 25-52347273/ +86 25-51570518
  • Fax: +86 25-52337971
  • Address: Unispec Chemicals Co.
    Technology Building,
    No.5 New Model Road,
    Nanjing, China P.C.:210009 null,nullChina
Contact Supplier

83-88-5 EC-501-25-G RIBOFLAVIN

  • United Kingdom AGTC Bioproducts Ltd [Manufacturer]
  • Tel: +44(0)1482646020
  • Fax: +44(0)1482646013
  • Address: AGTC Bioproducts Ltd
    Unit 4 Fleet Business Park, Hessle,
    ERY, HU13 9LX
    United Kingdom null,nullUnited Kingdom
Contact Supplier

83-88-5 Vitamin B2

  • China Huei-Ho International Co., Ltd. [Importer/Exporter]
  • Tel: +86-(21)-6273-7219, 6273-6279
  • Fax: +86-(21)-6129-4387, 62735948
  • Address: 20B,No.2,Lane 600,Peakway Tower,Tianshan Road, Shanghai, shanghai 200051, null,ShanghaiChina
Contact Supplier

83-88-5 Riboflavin

Contact Supplier

83-88-5 Vitamin B2

  • China Chemfar Ltd. null
  • Fax: 86-571-87859289
  • Address: 16E,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China null,nullChina
Contact Supplier

83-88-5 VITAMIN B2

Contact Supplier

83-88-5 Vitamin B2

Contact Supplier

Select to

References of Riboflavin
Title: Riboflavin
CAS Registry Number: 83-88-5
Synonyms: Vitamin B2; lactoflavine; vitamin G; 7,8-dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine; 7,8-dimethyl-10-ribitylisoalloxazine
Trademarks: Beflavin (Roche); Flavaxin (Winthrop)
Molecular Formula: C17H20N4O6
Molecular Weight: 376.36
Percent Composition: C 54.25%, H 5.36%, N 14.89%, O 25.51%
Literature References: Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, leafy vegetables. Richest natural source is yeast. Minute amounts present in all plant and animal cells. Occurs in the free form only in the retina of the eye, in whey, and in urine. Bioactive forms occurring in tissues and cells are riboflavin monophosphate and flavine-adenine dinucleotide, q.q.v. Syntheses: Karrer et al., Helv. Chim. Acta 18, 426, 522 (1935); Kuhn et al., Naturwissenschaften 23, 260 (1935); Howe, US 2807611 (1957 to Merck & Co.); F. Yoneda et al., J. Chem. Soc. Perkin Trans. 1 1978, 348. May also be produced by fermentation: Malzahn et al., US 2876169 (1959 to Grain Processing Corp.). Toxicity studies: Kuhn, Boulanger, Z. Physiol. Chem. 241, 233 (1936); K. Unna, J. G. Greslin, J. Pharmacol. Exp. Ther. 76, 75 (1942). Early reviews: Rosenberg in The Vitamins (New York, 1945); Sebrell, Harris, The Vitamins vol. III (Academic Press, New York, 1954) pp 299-402; Vogel-Knobloch, Chemie und Technik der Vitamine vol. II, part 1 (Enke, Stuttgart, 1955). Review of metabolism: Rivlin, N. Engl. J. Med. 283, 463 (1970). Review of extraction and assay methods: Pearson, The Vitamins vol. VII, P. Gy?rgy, W. N. Pearson, Eds. (Academic Press, New York, 2nd ed., 1967) pp 99-136. Comprehensive reviews: ibid. vol. V, pp 1-96 (1972); F. J. Al-Shammary et al., Anal. Profiles Drug Subs. 19, 429-476 (1990).
Properties: Fine orange-yellow needles from 2N acetic acid, alcohol, water, or pyridine. Dec at 278-282° (darkens at about 240°). Three different crystal forms having different solubilities in water: Dale, US 2603633; US 2797215. [a]D25 -112 to -122° (50 mg in 2 ml 0.1N alcoholic NaOH dil to 10 ml with water). Absorption max: 220-225, 266, 371, 444, 475 nm. One gram dissolves in from 3000 to about 15,000 ml of water, the variations in the soly being due to differences in the crystal structure. Soly in alcohol (27.5°): 0.0045 g/100 ml of abs ethanol. Slightly sol in cyclohexanol, amyl acetate, benzyl alcohol, phenol; very sol in dil alkalies (with decompn). Insol in ether, chloroform, acetone, benzene. pKa 10.2; pKb 1.7. pH of satd aq soln: ~6. Isoelectric pt: pH 6. Aq solns are yellow showing a green fluoresence with max at 565 nm. Sensitive to alkalies; stable to mineral acids in the dark. Visible or ultraviolet irradiation of alkaline solns causes the formation of lumiflavine, q.v., whereas irradiation of acid or neutral solns gives rise to the production of lumichrome, q.v., together with varying amounts of lumiflavine. LD50 in rats (g/kg): >10 orally, 5.0 s.c., 0.56 i.p. (Unna, Greslin).
pKa: pKa 10.2; pKb 1.7
Optical Rotation: [a]D25 -112 to -122° (50 mg in 2 ml 0.1N alcoholic NaOH dil to 10 ml with water)
Absorption maximum: Absorption max: 220-225, 266, 371, 444, 475 nm
Toxicity data: LD50 in rats (g/kg): >10 orally, 5.0 s.c., 0.56 i.p. (Unna, Greslin)
 
Derivative Type: 2¢,3¢,4¢,5¢-Tetrabutyrate
CAS Registry Number: 752-56-7
Trademarks: Bituvitan (Hishiyama); Eyekas (Showa Shinyaku); Hibon (Tokyo Tanabe); Lacflavin (Towa Yakuhin); Ribolact (Taiho); Wakaflavin L (Wakamoto); Viras (Mect)
Molecular Formula: C33H44N4O10
Molecular Weight: 656.72
Percent Composition: C 60.35%, H 6.75%, N 8.53%, O 24.36%
 
Therap-Cat: Vitamin (enzyme cofactor).
Therap-Cat-Vet: Vitamin (enzyme cofactor).
Keywords: Enzyme Cofactor; Vitamin/Vitamin Source; Vitamin B2.