Home > Name List By 2 > 2-[2, 3-dihydro-1H-inden-2-yl-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2- yl]amino]propanoyl]amino]acetic acid Germany

CAS No 83435-66-9 , 2-[2,
3-dihydro-1H-inden-2-yl-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-
yl]amino]propanoyl]amino]acetic acid Search by region : Germany

  • Name: 2-[2,
    3-dihydro-1H-inden-2-yl-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-
    yl]amino]propanoyl]amino]acetic acid
  • Synonyms: Glycine; Delaprilum [Latin]; N-((1S)-1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl-N-(2,3-dihydro-1H-inden-2-yl)-;2-[2,
    3-dihydro-1H-inden-2-yl-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-
    yl]amino]propanoyl]amino]acetic acid; 83435-66-9;Alindapril;
  • CAS Registry Number:
  • Flash Point: 352.7°C
  • Boiling Point: 659.7°C at 760 mmHg
  • Density: 1.22g/cm3
  • Refractive index: 1.595
  • Flash Point: 352.7°C
  • Molecular Weight: 452.54268
  • InchiKey: WOUOLAUOZXOLJQ-MBSDFSHPSA-N
  • InChI: InChI=1S/C26H32N2O5/c1-3-33-26(32)23(14-13-19-9-5-4-6-10-19)27-18(2)25
    (31)28(17-24(29)30)22-15-20-11-7-8-12-21(20)16-22/h4-12,18,22-23,27H,3,
    13-17H2,1-2H3,(H,29,30)/t18-,23-/m0/s1
  • Molecular Formula: C26H32N2O5
  • Molecular Structure:CAS No:83435-66-9 2-[2,<br />3-dihydro-1H-inden-2-yl-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-<br />yl]amino]propanoyl]amino]acetic acid

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83435-66-9 Delapril

  • Delapril
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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References of 2-[2,
3-dihydro-1H-inden-2-yl-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-
yl]amino]propanoyl]amino]acetic acid
Title: Delapril
CAS Registry Number: 83435-66-9
CAS Name: N-[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-N-(2,3-dihydro-1H-inden-2-yl)glycine
Synonyms: N-[N-[(S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-N-(indan-2-yl)glycine; ethyl (S)-2-[[(S)-1-[(carboxymethyl)-2-indanylcarbamoyl]ethyl]amino]-4-phenylbutyrate; alindapril; indalapril
Molecular Formula: C26H32N2O5
Molecular Weight: 452.54
Percent Composition: C 69.01%, H 7.13%, N 6.19%, O 17.68%
Literature References: Angiotensin-converting enzyme (ACE) inhibitor. Prepn: Y. Oka et al., EP 51391; eidem, US 4385051 (1982, 1983 both to Takeda); J. T. Suh et al., Eur. J. Med. Chem. - Chim. Ther. 20, 563 (1985); A. Miyake et al., Chem. Pharm. Bull. 34, 2852 (1986). Pharmacology in animals: Y. Inada et al., Jpn. J. Pharmacol. 42, 1 (1986); eidem, ibid., 99. Pharmacology and metabolism in humans: T. Ogihara et al., Curr. Ther. Res. 41, 809 (1987). Pharmacokinetics and evaluation in hypertension: H. Shionoiri et al., Clin. Pharmacol. Ther. 41, 74 (1987).
 
Derivative Type: Hydrochloride
CAS Registry Number: 83435-67-0
Manufacturers' Codes: CV-3317; REV-6000A
Trademarks: Adecut (Takeda); Cupressin (Takeda)
Molecular Formula: C26H32N2O5.HCl
Molecular Weight: 489.00
Percent Composition: C 63.86%, H 6.80%, N 5.73%, O 16.36%, Cl 7.25%
Properties: Colorless plates from acetone + hydrochloric acid, mp 166-170° (dec). [a]D22 +18.5° (c = 1 in methanol).
Melting point: mp 166-170° (dec)
Optical Rotation: [a]D22 +18.5° (c = 1 in methanol)
 
Therap-Cat: Antihypertensive.
Keywords: ACE-Inhibitor; Antihypertensive; N-Carboxyalkyl (peptide/lactam) Derivatives.