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CAS No 86168-78-7 , Sermorelin

  • Name: Sermorelin
  • Synonyms: Sermorelin (INN);Sermorelin; Sermoreline;Sermorelina; Sermorelinum; Geref (TN); Sermorelina [Spanish]; Sermorelinum [Latin]; Sermoreline [French];
  • CAS Registry Number:
  • Density: 1.45 g/cm3
  • Refractive index: 1.649
  • Molecular Weight: 3357.88214
  • InchiKey: WGWPRVFKDLAUQJ-UHFFFAOYSA-N
  • InChI: InChI=1S/C149H246N44O42S/c1-20-77(13)116(191-122(211)81(17)168-132(221)
    104(66-113(204)205)178-121(210)79(15)167-123(212)88(152)62-84-39-43-86
    (198)44-40-84)145(234)185-102(63-83-32-23-22-24-33-83)138(227)193-118(82
    (18)197)146(235)186-103(65-111(155)202)137(226)189-108(71-196)142(231)
    182-101(64-85-41-45-87(199)46-42-85)136(225)175-93(38-31-56-165-149(161)
    162)126(215)174-91(35-26-28-53-151)131(220)190-115(76(11)12)143(232)184-
    97(58-72(3)4)124(213)166-68-112(203)170-94(47-49-109(153)200)128(217)
    180-100(61-75(9)10)135(224)188-106(69-194)140(229)169-80(16)120(209)172-
    92(37-30-55-164-148(159)160)125(214)173-90(34-25-27-52-150)127(216)179-
    99(60-74(7)8)134(223)181-98(59-73(5)6)133(222)176-95(48-50-110(154)201)
    129(218)183-105(67-114(206)207)139(228)192-117(78(14)21-2)144(233)177-96
    (51-57-236-19)130(219)187-107(70-195)141(230)171-89(119(156)208)36-29-
    54-163-147(157)158/h22-24,32-33,39-46,72-82,88-108,115-118,194-199H,
    20-21,25-31,34-38,47-71,150-152H2,1-19H3,(H2,153,200)(H2,154,201)(H2,
    155,202)(H2,156,208)(H,166,213)(H,167,212)(H,168,221)(H,169,229)(H,170,
    203)(H,171,230)(H,172,209)(H,173,214)(H,174,215)(H,175,225)(H,176,
    222)(H,177,233)(H,178,210)(H,179,216)(H,180,217)(H,181,223)(H,182,
    231)(H,183,218)(H,184,232)(H,185,234)(H,186,235)(H,187,219)(H,188,
    224)(H,189,226)(H,190,220)(H,191,211)(H,192,228)(H,193,227)(H,204,
    205)(H,206,207)(H4,157,158,163)(H4,159,160,164)(H4,161,162,165)
  • Molecular Formula: C149H246N44O42S
  • Molecular Structure:CAS No:86168-78-7 Sermorelin

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References of Sermorelin
Title: Sermorelin
CAS Registry Number: 86168-78-7
Synonyms: Human growth hormone-releasing factor(1-29)amide; human pancreatic somatoliberin(1-29)amide; GRF(1-29)NH2; hpGRF(1-29)NH2
Manufacturers' Codes: SM-8144
Trademarks: Geref (Serono); Groliberin (Kabi)
Molecular Formula: C149H246N44O42S
Molecular Weight: 3357.88
Percent Composition: C 53.30%, H 7.38%, N 18.35%, O 20.01%, S 0.95%
Literature References: Amidated fragment of human somatoliberin, q.v. Characterization of in vitro activity: J. Rivier et al., Nature 300, 276 (1982). Prepn: N. Ling et al., Biochem. Biophys. Res. Commun. 123, 854 (1984); J. E. F. Rivier et al., US 4703035 (1987 to Salk Inst. Biol. Stud.). Clinical pharmacology: M. Losa et al., Klin. Wochenschr. 62, 1140 (1984). Clinical evaluation in growth hormone deficiency: M. B. Ranke et al., Eur. J. Pediatr. 145, 485 (1986); R. Hümmelink et al., Acta Paediatr. Scand. Suppl. 331, 48 (1987). Field trial in pigs and dairy heifers: D. Petitclerc et al., J. Anim. Sci. 65, 996 (1987).
Properties: [a]D20 -63.1° (c = 1 in 30% acetic acid).
Optical Rotation: [a]D20 -63.1° (c = 1 in 30% acetic acid)
Therap-Cat: Growth hormone releasing factor.
Keywords: Growth Hormone Releasing Factor.