Home > Name List By other > (2S,3aR, 7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl] -2,3,3a,4,5,6,7,7a-octahydroindole-2-carbox... China

CAS No 87679-37-6 , (2S,3aR,
7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]
-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid Search by region : China

  • Name: (2S,3aR,
    7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]
    -2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid
  • Synonyms: Gopten;Mavik; Odrik; Trandolaprilum; 87679-37-6; Udrik; Trandolaprilum [Latin]; Preran; Odric;(2S,3aR,
    7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]
    -2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid;
  • CAS Registry Number:
  • Melting Point: 122-123 ºC
  • Flash Point: 332.4 ºC
  • Boiling Point: 626 ºC at 760 mmHg
  • Density: 1.181 g/cm3
  • Refractive index: 1.549
  • Water Solubility: Insoluble in water
  • Flash Point: 332.4 ºC
  • Molecular Weight: 430.53716
  • InchiKey: VXFJYXUZANRPDJ-WTNASJBWSA-N
  • InChI: InChI=1S/C24H34N2O5/c1-3-31-24(30)19(14-13-17-9-5-4-6-10-17)25-16(2)22
    (27)26-20-12-8-7-11-18(20)15-21(26)23(28)29/h4-6,9-10,16,18-21,25H,3,
    7-8,11-15H2,1-2H3,(H,28,29)/t16-,18+,19-,20-,21-/m0/s1
  • Molecular Formula: C24H34N2O5
  • Molecular Structure:CAS No:87679-37-6 (2S,3aR,<br />7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]<br />-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid

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87679-37-6 Trandolapril

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87679-37-6 Trandolapril

  • China HuaiBei SanHe Developing Co., Ltd. [Manufacturers]
  • Tel: 86-561-3191113
  • Fax: +86-561-3192253
  • Address: Room 201,Building ZY-1,GuCheng Road,Huaibei,Anhui,China null,anhuiChina
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87679-37-6 TRANDOLAPRIL

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
  • Fax: +86-571-81956190
  • Address: 425 MOGAN HILL ROAD ,
    HANGZHOU, 310011 CHINA null,nullChina
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87679-37-6 Trandolapril

  • China Facus Pharmaceutical Co., Ltd. [Manufacturers]
  • Tel: +86-(574)-6237-8411
  • Fax: +86-(574)-6237-8410
  • Address: 24Fl, Yuanjing Building, Beilun, Ningbo, Zhejiang 315800, Ningbo,ZhejiangChina
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87679-37-6 Trandolapril

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87679-37-6 Trandolapril

  • China Hangzhou Pharma & Chem Co.,Ltd. [Manufacturers]
  • Tel: +86-571-87040515
  • Fax: +86-571-87214761
  • Address: Rm.1201,QinglianBldg.No,139QingchunRd,HangzhouCity,Zhejiang,China Hangzhou,ZhejiangChina
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87679-37-6 trandolapril

  • China Luna Chemicals Co.,Ltd. null
  • Fax: +86-571-85775960
  • Address: 1502-1503,No.310 North Zhong Shan Rd., Hangzhou,China null,nullChina
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87679-37-6 Trandolapril

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87679-37-6 Trandolapril

  • China ZHEJIANG HOLYPHARM BIOTECH CO.,LTD [Manufacturers]
  • Tel: 86-533-8585678
  • Fax: 86-57187357695
  • Address: Room C 13th Floor, West Wing International Garden, No.160 Tianmushan Road, Xihu District, Hangzhou City, China null,nullChina
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87679-37-6 Trandolapril

  • China Levachem Co. Ltd. [Manufacturers]
  • Tel: 86-25-83247442 / 443 / 445 / 446 / 447
  • Fax: +86-25-83247441
  • Address: 2112, SuNing Universal Mansion, 188 Guangzhou Road, Nanjing-210024, China Nanjing,jiangsuChina
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References of (2S,3aR,
7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]
-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid
Title: Trandolapril
CAS Registry Number: 87679-37-6
CAS Name: (2S,3aR,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid
Synonyms: (3aR,7aS)-1-[N-[1(S)-(ethoxycarbonyl)-3-phenylpropyl]-(S)-alanyl]octahydroindole-2(S)-carboxylic acid; (2S,3aR,7aS)-1-[(S)-N-[(S)-1-carboxy-3-phenylpropyl]alanyl]hexahydro-2-indolinecarboxylic acid 1-ethyl ester
Manufacturers' Codes: RU-44570
Trademarks: Mavik (Abbott); Odrik (Aventis); Gopten (Abbott)
Molecular Formula: C24H34N2O5
Molecular Weight: 430.54
Percent Composition: C 66.95%, H 7.96%, N 6.51%, O 18.58%
Literature References: Angiotensin converting enzyme (ACE) inhibitor. Prepn: H. Urbach et al., EP 84164; eidem, US 4933361 (1983, 1990 both to Hoechst). Enzyme inhibition and pharmacology: N. L. Brown et al., Eur. J. Pharmacol. 148, 79 (1988). Clinical pharmacology: F. De Ponti et al., Eur. J. Clin. Pharmacol. 40, 149 (1991). Clinical trial in prevention of death after myocardial infarction: L. Kober et al., N. Engl. J. Med. 333, 1670 (1995). Series of articles on pharmacology and clinical trials: Am. J. Hypertens. 8, 63S-74S (1995). Clinical trial in diabetic neuropathy: R. A Malik et al., Lancet 352, 1978 (1998).
Properties: Colorless, crystalline solid, mp 125°. Sol in chloroform, dichloromethane, methanol.
Melting point: mp 125°
 
Derivative Type: Diacid
CAS Registry Number: 87679-71-8
Synonyms: Trandolaprilat
Manufacturers' Codes: RU-44403
Molecular Formula: C22H30N2O5
Molecular Weight: 402.48
Percent Composition: C 65.65%, H 7.51%, N 6.96%, O 19.88%
 
Therap-Cat: Antihypertensive.
Keywords: ACE-Inhibitor; Antihypertensive; N-Carboxyalkyl (peptide/lactam) Derivatives.