Home > Name List By 2 > 2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl] phenol

CAS No 89365-50-4 , 2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]
phenol

  • Name: 2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]
    phenol
  • Synonyms: Salmeterolum [Latin]; Aeromax; Serevent; HSDB 7315; GR 33343X;2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]
    phenol; Salmeterolum; 89365-50-4;Astmerole; SALMATEROL;
  • CAS Registry Number:
  • Density: 1.112 g/cm3
  • Safety Statements: A poison by inhalation. When heated to decomposition it emits toxic vapors of NOx.
  • Hazard Symbols: A poison by inhalation.
  • Molecular Weight: 415.56558
  • InchiKey: GIIZNNXWQWCKIB-UHFFFAOYSA-N
  • InChI: InChI=1S/C25H37NO4/c27-20-23-18-22(13-14-24(23)28)25(29)19-26-15-7-1-2-
    8-16-30-17-9-6-12-21-10-4-3-5-11-21/h3-5,10-11,13-14,18,25-29H,1-2,6-9,
    12,15-17,19-20H2
  • Molecular Formula: C25H37NO4
  • Molecular Structure:CAS No:89365-50-4 2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]<br />phenol

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References of 2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]
phenol
Title: Salmeterol
CAS Registry Number: 89365-50-4
CAS Name: 4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol
Synonyms: (±)-4-hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-m-xylene-a,a1-diol
Manufacturers' Codes: GR-33343X
Molecular Formula: C25H37NO4
Molecular Weight: 415.57
Percent Composition: C 72.25%, H 8.97%, N 3.37%, O 15.40%
Literature References: b2-Adrenergic agonist; structural analog of albuterol, q.v. Prepn: I. F. Skidmore et al., DE 3414752; eidem, US 4992474 (1984, 1991 both to Glaxo). Pharmacology: M. Johnson, Lung 168, Suppl., 115 (1990). Preliminary evaluations in asthma: A. Ullman et al., Am. Rev. Respir. Dis. 142, 571 (1990); O. P. Twentyman et al., Lancet 336, 1338 (1990). Review of pharmacology and therapeutic use: R. N. Brogden, D. Faulds, Drugs 42, 895-912 (1991).
Properties: mp 75.5-76.5°.
Melting point: mp 75.5-76.5°
 
Derivative Type: 1-Hydroxy-2-naphthoate
CAS Registry Number: 94749-08-3
Synonyms: Salmeterol xinafoate
Manufacturers' Codes: GR-33343G
Trademarks: Arial (Domp?; Salmetedur (Menarini); Serevent (GSK)
Molecular Formula: C25H37NO4.C11H8O3
Molecular Weight: 603.75
Percent Composition: C 71.62%, H 7.51%, N 2.32%, O 18.55%
Properties: mp 137-138°. Freely sol in methanol; slightly sol in ethanol, chloroform, isopropanol; sparingly sol in water.
Melting point: mp 137-138°
 
Therap-Cat: Bronchodilator.
Keywords: ?Adrenergic Agonist; Bronchodilator; Ephedrine Derivatives.