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CAS No 9004-61-9 , Hyaluronic acid Search by region : Japan

  • Name: Hyaluronic acid
  • Synonyms: Hyaluronic acid;hyaluronic acid sodium from*streptococcus zooepid; Hyaluronic acid from Cockscomb; Hyaluronic Acid;
  • CAS Registry Number:
  • Density: 1.78 g/cm3
  • Refractive index: 1.666
  • Safety Statements: 22-24/25
  • Hazard Symbols: B
  • EINECS: 232-678-0
  • Molecular Weight: 776.647
  • InChI: InChI=1/C28H44N2O23/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45)/t7-,8-,9-,10-,11-,12-,13+,14+,15-,16-,17-,18?,19?,20+,21+,22+,25-,26+,27-,28-/m1/s1
  • Molecular Formula: (C14H21NO11)n
  • Molecular Structure:CAS No:9004-61-9 Hyaluronic acid

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9004-61-9 hyaluronic acid

  • Japan Nacalai Tesque, Inc. [Manufacturers]
  • Tel: 81 75 251 1723 81-75-251-1730
  • Fax: 81-75-251-1763
  • Address: Nijo Karasuma, Nakagyo-ku Kyoto 604-0855 Japan Nakagyo-ku,KyotoJapan
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References of Hyaluronic acid
Title: Hyaluronic Acid
CAS Registry Number: 9004-61-9
Literature References: Unbranched high molecular weight polysaccharide made up of alternating glucuronic acid and N-acetyl glucosamine units. Present in the connective tissue of all vertebrates as the hyaluronate; in man high concentrations are found in skin, cartilage, in the umbilical cord, in vitreous body and in synovial fluid. Isoln and characterization: K. Meyer, J. W. Palmer, J. Biol. Chem. 107, 629 (1934); eidem, ibid. 114, 689 (1936). Structure: K. Meyer, Fed. Proc. 17, 1075 (1958). Crystal structure: I. C. M. Dea et al., Science 179, 560 (1973); E. D. T. Atkins, J. K. Sheehan, ibid. 562. Reviews: Tauber, Chemistry and Technology of Enzymes (New York, 1946); Meyer, Rapport in Adv. Enzymol. 13, 199 (1952); R. L. Whistler, E. J. Olson in Adv. Carbohydr. Chem. 12, 299 (1957). Review of role in various developmental processes: B. P. Toole, Cell Biology of Extracellular Matrix, E. D. Hay, Ed. (Plenum Press, New York, 1981) pp 259-288.
 
Derivative Type: Sodium salt
CAS Registry Number: 9067-32-7
Trademarks: ARTZ (Seikagaku); Connettivina (Fidia); Equron (Solvay); Healon (Pfizer); Healonid (Pfizer); Hyacid (Scanvet); Hyalgan (Fidia); Hyalovet (Fidia); Hyonate (Bayer); Ial (Fidia); Opegan (Santen); Provisc (Alcon); Synacid (Sterivet)
Properties: [a]D25 -74° (c = 0.25 in water): Rapport et al., J. Am. Chem. Soc. 73, 2416 (1951).
Optical Rotation: [a]D25 -74° (c = 0.25 in water): Rapport et al., J. Am. Chem. Soc. 73, 2416 (1951)
 
Use: Surgical aid (ophthalmological).
Therap-Cat-Vet: Adjunct in treatment of noninfectious synovitis. Osteoarthritis in dogs and horses.